4-METHOXY-3-METHYLBENZYL CHLORIDE
- Product Name
- 4-METHOXY-3-METHYLBENZYL CHLORIDE
- CAS No.
- 60736-71-2
- Chemical Name
- 4-METHOXY-3-METHYLBENZYL CHLORIDE
- Synonyms
- -1-methoxy-2-methylbenzene;4-METHOXY-3-METHYLBENZYL CHLORIDE;4-Methoxy-3-methylbenzyl chloride ,98%;4-(chloroMethyl)-1-Methoxy-2-Methylbenzene;4-(Chloromethyl)-2-methylphenyl methyl ether;Benzene, 4-(chloromethyl)-1-methoxy-2-methyl-;Benzene, 4-(chloromethyl)-1-methoxy-2-methyl- (9CI);4-Methoxy-3-methylbenzyl chloride (stabilised with calcium carbonate);4-METHOXY-3-METHYLBENZYL CHLORIDE (STABILIZED WITH CALCIUM CARBONATE);4-Methoxy-3-methylbenzyl chloride, 98% (Stabilized with Calcium carbote)
- CBNumber
- CB7244537
- Molecular Formula
- C9H11ClO
- Formula Weight
- 170.64
- MOL File
- 60736-71-2.mol
4-METHOXY-3-METHYLBENZYL CHLORIDE Property
- Boiling point:
- 143°C 25mm
- Density
- 1,11 g/cm3
- storage temp.
- Storage temp. 2-8°C
- Appearance
- Colorless to light yellow Liquid
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- RIDADR
- UN1760
- HazardClass
- 8
- PackingGroup
- III
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
- Precautionary statements
-
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- C597898
- Product name
- 4-(Chloromethyl)-1-methoxy-2-methylbenzene
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- C597898
- Product name
- 4-(Chloromethyl)-1-methoxy-2-methylbenzene
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 2707-5-03
- Product name
- 4-Methoxy-3-methylbenzyl chloride (Stabilized with Calcium carbonate)
- Purity
- 98%
- Packaging
- 250mg
- Price
- $52
- Updated
- 2021/12/16
- Product number
- 9079AB
- Product name
- 4-(Chloromethyl)-1-methoxy-2-methylbenzene
- Packaging
- 250mg
- Price
- $104
- Updated
- 2021/12/16
- Product number
- 2707-5-03
- Product name
- 4-Methoxy-3-methylbenzyl chloride (Stabilized with Calcium carbonate)
- Purity
- 98%
- Packaging
- 1g
- Price
- $106
- Updated
- 2021/12/16
4-METHOXY-3-METHYLBENZYL CHLORIDE Chemical Properties,Usage,Production
Synthesis
67-72-1
114787-91-6
60736-71-2
The general procedure for the synthesis of 4-methoxy-3-methylbenzyl chloride from hexachloroethane and 4-methoxy-3-methylbenzyl alcohol is as follows: to a stirred solution of 4-methoxy-3-methylbenzyl alcohol (2.31 g, 15.18 mmol, 1 eq.) in anhydrous methylene chloride (50 mL, 0.3 M) was added hexachloroethane (3.59 g, 15.18 mmol, 1 eq.) and triphenylphosphine (3.98 g, 15.18 mmol, 1 eq.) in sequence. ) and triphenylphosphine (3.98 g, 15.18 mmol, 1 eq.). The reaction mixture was stirred at room temperature overnight. After completion of the reaction, the mixture was transferred to a partition funnel, washed sequentially with water and brine, the organic phase was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: 30% ethyl acetate/hexane) to afford the target product 4-methoxy-3-methylbenzyl chloride (2.59 g, 100% yield). The structure of the product was confirmed by 1H NMR (CDCl3, 400 MHz): δ 7.16 (m, 2H), 6.76 (d, 1H, J = 8.10 Hz), 4.52 (s, 2H), 3.81 (s, 3H), 2.19 (s, 3H).
References
[1] Patent: US2004/72838, 2004, A1
4-METHOXY-3-METHYLBENZYL CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
4-METHOXY-3-METHYLBENZYL CHLORIDE Suppliers
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