5-BROMO-3-METHYL-2-(MORPHOLINO)PYRIDINE
- Product Name
- 5-BROMO-3-METHYL-2-(MORPHOLINO)PYRIDINE
- CAS No.
- 566158-47-2
- Chemical Name
- 5-BROMO-3-METHYL-2-(MORPHOLINO)PYRIDINE
- Synonyms
- 5-BROMO-3-METHYL-2-(MORPHOLINO)PYRIDINE;4-(5-Bromo-3-methyl-2-pyridyl)morpholine;Morpholine, 4-(5-broMo-3-Methyl-2-pyridinyl)-
- CBNumber
- CB72455959
- Molecular Formula
- C10H13BrN2O
- Formula Weight
- 257.13
- MOL File
- 566158-47-2.mol
5-BROMO-3-METHYL-2-(MORPHOLINO)PYRIDINE Property
- Density
- 1.441
- storage temp.
- 2-8°C
Safety
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- FB154348
- Product name
- 5-Bromo-3-methyl-2-(morpholino)pyridine
- Packaging
- 100mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- FB154348
- Product name
- 5-Bromo-3-methyl-2-(morpholino)pyridine
- Packaging
- 250mg
- Price
- $170
- Updated
- 2021/12/16
- Product number
- 052107
- Product name
- 4-(5-Bromo-3-methyl-2-pyridinyl)morpholine
- Packaging
- 500mg
- Price
- $237
- Updated
- 2021/12/16
- Product number
- FB154348
- Product name
- 5-Bromo-3-methyl-2-(morpholino)pyridine
- Packaging
- 500mg
- Price
- $295
- Updated
- 2021/12/16
- Product number
- FB154348
- Product name
- 5-Bromo-3-methyl-2-(morpholino)pyridine
- Packaging
- 1g
- Price
- $511
- Updated
- 2021/12/16
5-BROMO-3-METHYL-2-(MORPHOLINO)PYRIDINE Chemical Properties,Usage,Production
Synthesis
110-91-8
29312-98-9
566158-47-2
K2CO3 (5.5 g, 39.6 mmol) was added as 5-bromo-2-fluoro-3-methylpyridine (2.5 g, 13.2 mmol) and morpholine (3.4 g, 39.2 mmol) dissolved in 40 mL of DMSO. The reaction mixture was heated to 120 °C and stirred for 16 hours. After the reaction was completed, the mixture was cooled to room temperature. 200 mL of water was added to the reaction mixture and extracted with ethyl acetate (150 mL x 3). The organic layers were combined, washed sequentially with 150 mL of water and 150 mL of brine, and dried with anhydrous Na2SO4. The organic layer was concentrated under reduced pressure to afford the target compound 5-bromo-3-methyl-2-(morpholinato)pyridine (1.8 g, 53% yield) as a white solid.LC-MS detection: [M + H]+ = 257.0.
References
[1] Patent: US2016/176882, 2016, A1. Location in patent: Paragraph 0427; 0428
[2] Patent: WO2017/221100, 2017, A1. Location in patent: Paragraph 00217
5-BROMO-3-METHYL-2-(MORPHOLINO)PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
5-BROMO-3-METHYL-2-(MORPHOLINO)PYRIDINE Suppliers
- Tel
- --
- Fax
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- akos@akosgmbh.eu
- Country
- Germany
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- 1061
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