ChemicalBook > CAS DataBase List > 8-PRENYLGENISTEIN

8-PRENYLGENISTEIN

Product Name: 8-PRENYLGENISTEIN
CAS No.: 104691-86-3
Chemical Name: 8-PRENYLGENISTEIN
Synonyms: Lupiwighteone;Luncheonette;8-PRENYLGENISTEIN;8-Isopentenylgenistein;Lupiwighteone, 10 mM in DMSO;4',5,7-Trihydroxy-8-prenylisoflavone;4',5,7-Trihydroxy-8-isopentenylisoflavone;5,7-Dihydroxy-3-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one;3-(4-Hydroxyphenyl)-5,7-dihydroxy-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;5,7-Dihydroxy-3-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
CBNumber: CB7246036
Molecular Formula: C20H18O5
Formula Weight: 338.35
MOL File: Mol file

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8-PRENYLGENISTEIN Property

Melting point:: 133-135℃
Boiling point:: 583.5±50.0 °C(Predicted)
Density: 1.351±0.06 g/cm3(Predicted)
storage temp.: 4°C, protect from light
solubility: DMSO : 100 mg/mL (295.55 mM; Need ultrasonic)
form: Powder
pka: 6.62±0.20(Predicted)
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: L478020
Product name: Lupiwighteone
Packaging: 10mg
Price: $715
Updated: 2021/12/16

TRC

Product number: L478020
Product name: Lupiwighteone
Packaging: 25mg
Price: $1595
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP137754
Product name: 8-Prenylgenistein
Packaging: 1mg
Price: $325
Updated: 2021/12/16

AK Scientific

Product number: 9654AF
Product name: Lupiwighteone
Packaging: 1mg
Price: $488
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP137754
Product name: 8-Prenylgenistein
Packaging: 2mg
Price: $500
Updated: 2021/12/16

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8-PRENYLGENISTEIN Chemical Properties,Usage,Production

Uses

Lupiwighteone is a natural product derivative of Genistein (G350000). Genistein exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol.

Definition

ChEBI: Lupiwighteone is a member of isoflavones.

target

PARP | Bcl-2/Bax | Caspase | Akt | CDK | ROS | P450 (e.g. CYP17)

8-PRENYLGENISTEIN Preparation Products And Raw materials

Raw materials

Preparation Products

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104691-86-3, 8-PRENYLGENISTEINRelated Search:

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8-PRENYLGENISTEIN

5,7-Dihydroxy-3-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one

3-(4-Hydroxyphenyl)-5,7-dihydroxy-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one

4',5,7-Trihydroxy-8-isopentenylisoflavone

4',5,7-Trihydroxy-8-prenylisoflavone

8-Isopentenylgenistein

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4H-1-Benzopyran-4-one,5,7-dihydroxy-3- (4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-

PI3K,Apoptosis,antioxidant,Inhibitor,isoflavone,mTOR,antimicrobial,Akt,inhibit,Lupiwighteone,8-prenylgenistein

5,7-Dihydroxy-3-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one

Lupiwighteone, 10 mM in DMSO

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