ChemicalBook > CAS DataBase List > 3-HYDROXYFLAVONE

3-HYDROXYFLAVONE

Product Name
3-HYDROXYFLAVONE
CAS No.
577-85-5
Chemical Name
3-HYDROXYFLAVONE
Synonyms
FLAVONOL;3-HF;3-FLAVONOL;FLAVON-3-OL;AURORA 20058;3-hydroxy-flavon;3-HYDROXYFLAVONE;HYDROXYFLAVONE, 3-;Flavone, 3-hydroxy-;TIMTEC-BB SBB000767
CBNumber
CB4414838
Molecular Formula
C15H10O3
Formula Weight
238.24
MOL File
577-85-5.mol
More
Less

3-HYDROXYFLAVONE Property

Melting point:
171-172 °C (lit.)
Boiling point:
320.83°C (rough estimate)
Density 
1.2653 (rough estimate)
refractive index 
1.5740 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO: 1 mg/ml
pka
8.80±0.20(Predicted)
form 
powder to crystal
color 
White to Yellow to Green
Water Solubility 
Insoluble in water. Soluble in N,N-DMF and ethanol.
BRN 
15789
InChIKey
HVQAJTFOCKOKIN-UHFFFAOYSA-N
LogP
3.477 (est)
CAS DataBase Reference
577-85-5(CAS DataBase Reference)
EPA Substance Registry System
4H-1-Benzopyran-4-one, 3-hydroxy-2-phenyl- (577-85-5)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
RTECS 
LK8650000
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29322090
Hazardous Substances Data
577-85-5(Hazardous Substances Data)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H4280
Product name
3-Hydroxyflavone
Purity
≥98%
Packaging
5g
Price
$124
Updated
2024/03/01
TCI Chemical
Product number
H0379
Product name
3-Hydroxyflavone
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$40
Updated
2024/03/01
TCI Chemical
Product number
H0379
Product name
3-Hydroxyflavone
Purity
>98.0%(HPLC)(T)
Packaging
10g
Price
$192
Updated
2024/03/01
Alfa Aesar
Product number
A18110
Product name
3-Hydroxyflavone, 98+%
Packaging
1g
Price
$30.65
Updated
2024/03/01
Alfa Aesar
Product number
A18110
Product name
3-Hydroxyflavone, 98+%
Packaging
5g
Price
$109
Updated
2024/03/01
More
Less

3-HYDROXYFLAVONE Chemical Properties,Usage,Production

Chemical Properties

yellow fluffy powder

Uses

Reactant involved in:• ;Studies of photochemically-induced dioxygenase-type CO-release reactivity1• ;Phase-transfer protection and deprotection of hydroxychromones2• ;O-methylation with di-Me carbonate3Reactant involved in the synthesis of biologically active molecules including:• ;2-Chloropyridine derivatives for studies of antitumor agents and telomerase inhibitors4• ;Dihydrochromenopyrazines and chromenoquinoxalines5Involved in studies of its electrochemical properties using voltammetric methodologies6

Uses

3-Hydroxyflavone is a reactant involved in studies of photochemically-induced dioxygenase-type CO-release reactivity; phase-transfer protection and deprotection of hydroxychromones; and O-methylation with di-Me carbonate. As a reactant it is involved in the synthesis of biologically active molecules including 2-chloropyridine derivatives for studies of antitumor agents and telomerase inhibitors; dihydrochromenopyrazines and chromenoquinoxalines. It is also involved in studies of its electrochemical properties using voltammetric methodologies.

Definition

ChEBI: A monohydroxyflavone that is the 3-hydroxy derivative of flavone.

Synthesis Reference(s)

Tetrahedron Letters, 25, p. 5561, 1984 DOI: 10.1016/S0040-4039(01)81626-9

Purification Methods

Recrystallise it from MeOH (m 169.5-170o), EtOH, aqueous EtOH (m 167o) or hexane. It has also been purified by repeated sublimation under high vacuum, and dried at high vacuum pumping for at least one hour [Bruker & Kelly J Phys Chem 91 2856 1987]. [Beilstein 17 H 527, 17 I 268, 17 II 498, 17 III/IV 6428.]

3-HYDROXYFLAVONE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3-HYDROXYFLAVONE Suppliers

Zhengzhou kangnuochenrui Chemical Technology Co.,Ltd
Tel
18210788515
Fax
18210788515
Email
zhuzixin999@163.c0m
Country
China
ProdList
2955
Advantage
55
Yantai ShengKailun Chemical Technology Co., Ltd.
Tel
13356901049
Fax
QQ:1025383091
Email
3119594100@qq.com
Country
China
ProdList
7959
Advantage
55
Yantai Sheng Kai Lun Biological Products Co. , Ltd.
Tel
3119594100
Email
mark@sklnchem.cn
Country
China
ProdList
15384
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
More
Less

View Lastest Price from 3-HYDROXYFLAVONE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
3-HYDROXYFLAVONE 577-85-5
Price
US $8890.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
1T
Release date
2020-07-06
Career Henan Chemical Co
Product
3-HYDROXYFLAVONE 577-85-5
Price
US $1.00/kg
Min. Order
1g
Purity
99%
Supply Ability
100KG
Release date
2018-12-25

577-85-5, 3-HYDROXYFLAVONERelated Search:


  • AURORA 20058
  • FLAVON-3-OL
  • TIMTEC-BB SBB000767
  • 3-hydroxy-2-phenyl-4h-1-benzopyran-4-on
  • 3-Hydroxy-2-phenyl-4H-chromen-4-one
  • 3-hydroxy-flavon
  • Flavone, 3-hydroxy-
  • FLAVONOL
  • HYDROXYFLAVONE, 3-
  • 3-FLAVONOL
  • 3-HYDROXA-2-PHENYLCHROMONE
  • 3-HF
  • 3-HYDROXY-2-PHENYLCHROMONE
  • 3-HYDROXYFLAVONE
  • 3-Hydroxy-2-phenyl-4H-1-benzopyran-4-one
  • 3-Hydroxyflavone,99%
  • HYDROXYFLAVONE, 3-(RG)
  • 4H-1-Benzopyran-4-one, 3-hydroxy-2-phenyl-
  • 3-Hydroxyflavone, 98+%
  • 3-Hydroxy-2-phenyl-4H-chromen-4-one, 3-Hydroxy-4-oxo-2-phenyl-4H-1-benzopyran, Flavonol
  • 3-Hydroxyflavone, 98.5%
  • 3-Hydroxyflavone&gt
  • 3-Hydroxy Flavone 99% (3-Hydroxy-2-Phenylchromone)
  • 3-Hydroxyflavone (Flavonol)
  • 3-hydroxy-2-phenylchromen-4-one
  • FLAVONOL(3-HYDROXYFLAVONE)
  • 577-85-5
  • Heterocyclic Building Blocks
  • Flavonoids
  • Benzopyrans
  • Building Blocks
  • Inhibitors
  • Benzopyrans
  • Bioactive Small Molecules
  • Building Blocks
  • Cell Biology
  • Chemical Synthesis
  • H
  • Heterocyclic Building Blocks
  • Flavanols
  • Biochemistry
  • Flavonoids