(R)-3-METHOXY-PYRROLIDINE HYDROCHLORIDE
- Product Name
- (R)-3-METHOXY-PYRROLIDINE HYDROCHLORIDE
- CAS No.
- 474707-30-7
- Chemical Name
- (R)-3-METHOXY-PYRROLIDINE HYDROCHLORIDE
- Synonyms
- (R)-3-Methoxypyrrolidine HCl;(3R)-3-Methoxy-pyrrolidine HCl;(R)-3-METHOXY-PYRROLIDINE HYDROCHLORIDE;(3R)-3-METHOXYPYRROLIDINE HYDROCHLORIDE;(3R)-3-Methoxypyrrolidine hydrochloride (1:1);Pyrrolidine, 3-methoxy-, hydrochloride (1:1), (3R)-
- CBNumber
- CB72465417
- Molecular Formula
- C5H12ClNO
- Formula Weight
- 137.61
- MOL File
- 474707-30-7.mol
(R)-3-METHOXY-PYRROLIDINE HYDROCHLORIDE Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- light brown solid
- InChI
- InChI=1/C5H11NO.ClH/c1-7-5-2-3-6-4-5;/h5-6H,2-4H2,1H3;1H/t5-;/s3
- InChIKey
- SQMYKVUSWPIFEQ-USHJBNIQNA-N
- SMILES
- O([C@H]1CNCC1)C.Cl |&1:1,r|
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M333033
- Product name
- (R)-3-MethoxypyrrolidineHydrochloride
- Packaging
- 500mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- P000106028
- Product name
- (R)-3-Methoxypyrrolidine hydrochloride
- Purity
- 95%
- Packaging
- 250mg
- Price
- $33
- Updated
- 2021/12/16
- Product number
- P000106028
- Product name
- (R)-3-Methoxypyrrolidine hydrochloride
- Purity
- 95%
- Packaging
- 1g
- Price
- $83
- Updated
- 2021/12/16
- Product number
- Z4777
- Product name
- (R)-3-Methoxypyrrolidinehydrochloride
- Packaging
- 250mg
- Price
- $96
- Updated
- 2021/12/16
- Product number
- 4H56-5-R3
- Product name
- (3R)-3-Methoxypyrrolidine hydrochloride
- Packaging
- 1g
- Price
- $150
- Updated
- 2021/12/16
(R)-3-METHOXY-PYRROLIDINE HYDROCHLORIDE Chemical Properties,Usage,Production
Synthesis
549532-08-3
474707-30-7
The general procedure for the synthesis of (R)-3-methoxypyrrolidine hydrochloride from (R)-N-Boc-3-methoxytetrahydropyrrole was as follows: tert-butyl (R)-3-methoxypyrrolidine-1-carboxylate (1100 mg, 5.47 mmol) was dissolved in 4M HCl/dioxane solution (15 mL, 60 mmol), and the reaction was stirred for 16 hours at 20 °C. After completion of the reaction, the reaction mixture was concentrated to give the crude product (1000 mg, 7.27 mmol) as an oil. The structure of the product was confirmed by 1H NMR (CDCl3, 400 MHz) with the following chemical shifts: δH= 10.10-9.39 (m, 2H), 4.13-4.04 (m, 1H), 3.51-3.35 (m, 4H), 3.31 (s, 3H), 2.24-2.12 (m, 1H), 2.08-1.95 (m, 1H) .
References
[1] Patent: WO2005/49616, 2005, A1. Location in patent: Page/Page column 79
[2] Patent: WO2005/97799, 2005, A1. Location in patent: Page/Page column 125-126
[3] Patent: WO2004/37809, 2004, A1. Location in patent: Page 50
[4] Patent: WO2018/148745, 2018, A1. Location in patent: Page/Page column 168
(R)-3-METHOXY-PYRROLIDINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
(R)-3-METHOXY-PYRROLIDINE HYDROCHLORIDE Suppliers
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- info@chemsworth.com
- Country
- India
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- 6700
- Advantage
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- sales@ajchem.in
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- India
- ProdList
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View Lastest Price from (R)-3-METHOXY-PYRROLIDINE HYDROCHLORIDE manufacturers
- Product
- (R)-3-METHOXY-PYRROLIDINE HYDROCHLORIDE 474707-30-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 500kg/month
- Release date
- 2019-08-01