1H-Pyrazolo[3,4-b]pyridin-3(2H)-one
- Product Name
- 1H-Pyrazolo[3,4-b]pyridin-3(2H)-one
- CAS No.
- 2942-43-0
- Chemical Name
- 1H-Pyrazolo[3,4-b]pyridin-3(2H)-one
- Synonyms
- 1h-pyrazolo[3,4-b]pyridin-3-ol;1H-Pyrazolo[3,4-b]pyridin-3(2H);1H,2H-pyrazolo[3,4-b]pyridin-3-one;1H-Pyrazolo[3,4-b]pyridin-3(2H)-one;3-Hydroxy-1H-pyrazolo[3,4-b]pyridine;1H,2H,3H-pyrazolo[3,4-b]pyridin-3-one;1,2-dihydropyrazolo[3,4-b]pyridin-3-one;1,2-Dihydro-3H-pyrazolo[3,4-b]pyridin-3-one;3H-Pyrazolo[3,4-b]pyridin-3-one, 1,2-dihydro-
- CBNumber
- CB72471568
- Molecular Formula
- C6H5N3O
- Formula Weight
- 135.12
- MOL File
- 2942-43-0.mol
1H-Pyrazolo[3,4-b]pyridin-3(2H)-one Property
- Melting point:
- 234-236°
- Density
- 1.62±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 8.93±0.20(Predicted)
- Appearance
- Yellow to brown Solid
Safety
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403Store in a well-ventilated place.
N-Bromosuccinimide Price
- Product number
- FD142015
- Product name
- 1,2-Dihydro-3H-pyrazolo[3,4-b]pyridin-3-one
- Packaging
- 100mg
- Price
- $58
- Updated
- 2021/12/16
- Product number
- FD142015
- Product name
- 1,2-Dihydro-3H-pyrazolo[3,4-b]pyridin-3-one
- Packaging
- 250mg
- Price
- $115
- Updated
- 2021/12/16
- Product number
- Z4567
- Product name
- 1H-Pyrazolo[3,4-b]pyridin-3(2H)-one
- Packaging
- 250mg
- Price
- $159
- Updated
- 2021/12/16
- Product number
- FD142015
- Product name
- 1,2-Dihydro-3H-pyrazolo[3,4-b]pyridin-3-one
- Packaging
- 500mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- 048684
- Product name
- 1,2-Dihydro-3H-pyrazolo[3,4-b]pyridin-3-one
- Purity
- >95%
- Packaging
- 500mg
- Price
- $220
- Updated
- 2021/12/16
1H-Pyrazolo[3,4-b]pyridin-3(2H)-one Chemical Properties,Usage,Production
Synthesis
1452-94-4
2942-43-0
General procedure for the synthesis of 1H-pyrazolo[3,4-b]pyridin-3(2H)-one from ethyl 2-chloropyridine-3-carboxylate: a mixed solution of 5 g (26.94 mmol) of ethyl 2-chloropyridine-3-carboxylate and 4.76 g (80.82 mmol) of 85% hydrazine hydrate in 10 ml of ethanol was heated and refluxed for 6 hours. After completion of the reaction, the reaction mixture was concentrated. The product 3.5 g was obtained in 96% yield and the [M+H]+ peak was detected as 135.9 by mass spectrometry.
References
[1] Patent: WO2005/73199, 2005, A1. Location in patent: Page/Page column 31
[2] Patent: US2005/197348, 2005, A1. Location in patent: Page/Page column 10
1H-Pyrazolo[3,4-b]pyridin-3(2H)-one Preparation Products And Raw materials
Raw materials
Preparation Products
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