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1H-Pyrazolo[3,4-b]pyridin-3(2H)-one

Product Name
1H-Pyrazolo[3,4-b]pyridin-3(2H)-one
CAS No.
2942-43-0
Chemical Name
1H-Pyrazolo[3,4-b]pyridin-3(2H)-one
Synonyms
1h-pyrazolo[3,4-b]pyridin-3-ol;1H-Pyrazolo[3,4-b]pyridin-3(2H);1H,2H-pyrazolo[3,4-b]pyridin-3-one;1H-Pyrazolo[3,4-b]pyridin-3(2H)-one;3-Hydroxy-1H-pyrazolo[3,4-b]pyridine;1H,2H,3H-pyrazolo[3,4-b]pyridin-3-one;1,2-dihydropyrazolo[3,4-b]pyridin-3-one;1,2-Dihydro-3H-pyrazolo[3,4-b]pyridin-3-one;3H-Pyrazolo[3,4-b]pyridin-3-one, 1,2-dihydro-
CBNumber
CB72471568
Molecular Formula
C6H5N3O
Formula Weight
135.12
MOL File
2942-43-0.mol
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1H-Pyrazolo[3,4-b]pyridin-3(2H)-one Property

Melting point:
234-236°
Density 
1.62±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
8.93±0.20(Predicted)
Appearance
Yellow to brown Solid
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Safety

HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Matrix Scientific
Product number
048684
Product name
1,2-Dihydro-3H-pyrazolo[3,4-b]pyridin-3-one
Purity
>95%
Packaging
500mg
Price
$220
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD142015
Product name
1,2-Dihydro-3H-pyrazolo[3,4-b]pyridin-3-one
Packaging
1g
Price
$350
Updated
2021/12/16
Matrix Scientific
Product number
048684
Product name
1,2-Dihydro-3H-pyrazolo[3,4-b]pyridin-3-one
Purity
>95%
Packaging
1g
Price
$370
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD142015
Product name
1,2-Dihydro-3H-pyrazolo[3,4-b]pyridin-3-one
Packaging
2g
Price
$595
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0080114
Product name
1,2-DIHYDRO-3H-PYRAZOLO[3,4-B]PYRIDIN-3-ONE
Purity
95.00%
Packaging
1G
Price
$925.31
Updated
2021/12/16
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1H-Pyrazolo[3,4-b]pyridin-3(2H)-one Chemical Properties,Usage,Production

Synthesis

1452-94-4

2942-43-0

General procedure for the synthesis of 1H-pyrazolo[3,4-b]pyridin-3(2H)-one from ethyl 2-chloropyridine-3-carboxylate: a mixed solution of 5 g (26.94 mmol) of ethyl 2-chloropyridine-3-carboxylate and 4.76 g (80.82 mmol) of 85% hydrazine hydrate in 10 ml of ethanol was heated and refluxed for 6 hours. After completion of the reaction, the reaction mixture was concentrated. The product 3.5 g was obtained in 96% yield and the [M+H]+ peak was detected as 135.9 by mass spectrometry.

References

[1] Patent: WO2005/73199, 2005, A1. Location in patent: Page/Page column 31
[2] Patent: US2005/197348, 2005, A1. Location in patent: Page/Page column 10

1H-Pyrazolo[3,4-b]pyridin-3(2H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-Pyrazolo[3,4-b]pyridin-3(2H)-one Suppliers

China 39 India 1 United Kingdom 1 United States 5 Global 46
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58

2942-43-0, 1H-Pyrazolo[3,4-b]pyridin-3(2H)-oneRelated Search:


  • 1H-Pyrazolo[3,4-b]pyridin-3(2H)-one
  • 1,2-dihydropyrazolo[3,4-b]pyridin-3-one
  • 1,2-Dihydro-3H-pyrazolo[3,4-b]pyridin-3-one
  • 1h-pyrazolo[3,4-b]pyridin-3-ol
  • 3-Hydroxy-1H-pyrazolo[3,4-b]pyridine
  • 1H-Pyrazolo[3,4-b]pyridin-3(2H)
  • 1H,2H-pyrazolo[3,4-b]pyridin-3-one
  • 3H-Pyrazolo[3,4-b]pyridin-3-one, 1,2-dihydro-
  • 1H,2H,3H-pyrazolo[3,4-b]pyridin-3-one
  • 2942-43-0