Polyphyllin VI

Product Name: Polyphyllin VI
CAS No.: 55916-51-3
Chemical Name: Polyphyllin VI
Synonyms: Paris VI;Saponin Tb;Polyhyllin VI;Polyphyllin Ⅵ;product/154909;Polyphyllin VI;Paris saponin VI;17-Hydroxyparis V;Chonglou saponin Ⅵ;Polyphyllin F (Formosanin VI)
CBNumber: CB72484906
Molecular Formula: C39H62O13
Formula Weight: 738.9
MOL File: 55916-51-3.mol

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Polyphyllin VI Property

Melting point:: 216-220°C
Boiling point:: 871.2±65.0 °C(Predicted)
Density: 1.38
storage temp.: Hygroscopic, Refrigerator, under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 12.85±0.70(Predicted)
color: White to Off-White
InChIKey: WHWWQGPCTUQCMN-PICXMRMANA-N

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: P689480
Product name: PolyhyllinVI
Packaging: 10mg
Price: $150
Updated: 2021/12/16

Usbiological

Product number: 288354
Product name: Polyphyllin VI
Packaging: 1mg
Price: $333
Updated: 2021/12/16

Usbiological

Product number: 300815
Product name: Polyphyllin VI
Packaging: 10mg
Price: $523
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb104661
Product name: Polyphyllin VI
Purity: >98%,Standard References Grade
Packaging: 20mg
Price: $569.5
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 61339
Product name: PolyphyllinVI
Packaging: 10mg
Price: $650
Updated: 2021/12/16

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Polyphyllin VI Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder, easily soluble in methanol and water, derived from Paris polyphylla.

Uses

Polyhyllin VI is a natural saponin extracted from the plant, Rhizoma Paridis, and displays anti-proliferative activity in vivo. Used in the treatment of HepG2 cells for tumor mitigation.

in vivo

Polyphyllin VI (2-4 mg/kg; i.p.; five times a week for 4 weeks) inhibits the growth of lung cancer tumor xenografts^[1].
Polyphyllin VI (2.5-10 mg/kg; i.p.; 10 consecutive days) activates NLRP3 inflammasome in A549-bearing athymic nude mice^[3].

Animal Model:	A549 tumor xenografts subcutaneously inoculated into the right flank of the nude mice^[1]
Dosage:	2 mg/kg, 3 mg/kg, 4 mg/kg
Administration:	Intraperitoneal Injection (i.p.)
Result:	Resulted the reduction of tumor volume to 25.63%, 41.71%, and 40.41%, respectively, after 2 mg/kg, 3 mg/kg and 4 mg/kg treatment.

Animal Model:	A549 tumor xenografts subcutaneously inoculated into the right flank of the nude mice^[3]
Dosage:	2.5 mg/kg, 5 mg/kg, 10 mg/kg
Administration:	Intraperitoneal Injection (i.p.)
Result:	Showed the expression of NLRP3, caspase-1, IL-1β and GSDMD was increasing in a dose manner.

Polyphyllin VI Preparation Products And Raw materials

Raw materials

Preparation Products

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Polyphyllin VI Suppliers

China 176 India 1 United States 15 Global 192

Chengdu Gupte Biotechnology Co., Ltd.

Tel: 13881890404
Fax: 028-81711798
Email: 2851503757@qq.com
Country: China
ProdList: 2283
Advantage: 58

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

Aktin Chemicals, Inc.

Tel: 86-28-85159085
Fax: 86-28-85152372
Email: info@aktinchem.com
Country: China
ProdList: 297
Advantage: 62

Shenzhen Sungening Bio-Tech Co., Ltd

Tel: +86-0755-89668383
Fax: +86-0755-89594066/4038
Email: sales@sungening.com
Country: China
ProdList: 1319
Advantage: 65

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4790
Advantage: 58

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 5000
Advantage: 60

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

Shanghai Ruji Biology Technology Co., Ltd.

Tel: +86-21-65211385-8001 36031160
Fax: +86-21-65211385-8004
Email: sales@shruji.com
Country: China
ProdList: 3224
Advantage: 55

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
Advantage: 66

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View Lastest Price from Polyphyllin VI manufacturers

Career Henan Chemical Co

Product: Polyphyllin VI 55916-51-3
Price: US $2.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 10000kg
Release date: 2018-08-10

55916-51-3, Polyphyllin VIRelated Search:

Chonglou Saponin VII [(1aS)-1a,1bα,2,5aα,6,6aβ-Hexahydro-6α-[(E)-3-(4-hydroxy-3-methoxyphenyl)propenoyloxy]-1aβ-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]β-D-glucopyranoside Pectolinarigenin CYANIDIN CHLORIDE CASTICIN 1,7-Dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione 2β,3β,16α,23,24-Pentahydroxyolean-12-en-28-oic acid HOMOPLANTAGININ Homoharringtonine nardosinone Costunolide ELEUTHEROSIDE A Ginsengrootextract 20(R)-Ginsenoside Rg3 (25R)-3β-(2-O-α-L-Rhamnopyranosyl-β-D-glucopyranosyloxy)spirosta-5-ene POLYPHYLLIN D Polyphyllin VII Dioscin

Polyhyllin VI

(2R,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-4,5-Dihydroxy-2-(((2'R,4S,5'R,6aR,6bS,8aS,8bS,9S,11aS,12

Polyphyllin VI

Polyphyllin Ⅵ

Polyphyllin F (Polyphyllin VI)

Chonglou saponin Ⅵ

17-Hydroxyparis V

Paris saponin VI

Paris VI

Saponin Tb

product/154909

Polyphyllin F (Formosanin VI)

β-D-Glucopyranoside, (3β,25R)-17-hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-

b-D-Glucopyranoside, (3b,25R)-17-hydroxyspirost-5-en-3-yl2-O-(6-deoxy-a-L-mannopyranosyl)-

b-D-Glucopyranoside, (3b,25R)-17-hydroxyspirost-5-en-3-yl2-O...

Polyphyllin VI(Chonglou Saponin Ⅵ)

Polyphyllin VI, 10 mM in DMSO

55916-51-3

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract