ELEUTHEROSIDE A
Uses Description- Product Name
- ELEUTHEROSIDE A
- CAS No.
- 474-58-8
- Chemical Name
- ELEUTHEROSIDE A
- Synonyms
- DAUCOSTEROL;SITOGLUSIDE;ALEXANDRIN;lyoniside;β-sitosterol-3-O-β-D-glucopyranoside;daucosterin;Β-SITOSTEROL Β-D-GLUCOSIDE;Carrot glycoside;3-beta-(beta-d-glucopyranosyloxy)-stigmast-5-en;BSSG
- CBNumber
- CB1412792
- Molecular Formula
- C35H60O6
- Formula Weight
- 576.86
- MOL File
- 474-58-8.mol
ELEUTHEROSIDE A Property
- Melting point:
- 283～286℃
- Boiling point:
- 673.6±55.0 °C(Predicted)
- Density
- 1.13±0.1 g/cm3(Predicted)
- Flash point:
- 361℃
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly,Heated), Pyridine (Slightly, Sonicated)
- pka
- 12.91±0.70(Predicted)
- form
- Solid
- color
- Off-White to Pale Beige
- InChIKey
- YITHQYDRZAVJHB-WWJUBMRMSA-N
- LogP
- 8.615 (est)
Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- HS Code
- 29389090
- Toxicity
- LD50 intraperitoneal in mouse: 62mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 89851
- Product name
- β-Sitosterol β-D-glucoside
- Purity
- analytical standard
- Packaging
- 10mg
- Price
- $789
- Updated
- 2025/07/31
- Product number
- S497010
- Product name
- β-Sitosterol β-D-glucoside
- Packaging
- 25mg
- Price
- $275
- Updated
- 2021/12/16
- Product number
- 300212
- Product name
- Eleutheroside A
- Packaging
- 20mg
- Price
- $390
- Updated
- 2021/12/16
- Product number
- 107239
- Product name
- β-itosterolβ-D-glucoside
- Packaging
- 10mg
- Price
- $525
- Updated
- 2021/12/16
- Product number
- orb104914
- Product name
- Eleutheroside A
- Purity
- >98%,Standard References Grade
- Packaging
- 20mg
- Price
- $569.5
- Updated
- 2021/12/16
ELEUTHEROSIDE A Chemical Properties,Usage,Production
Uses
Daucosterol can be used as an efficient and inexpensive neuroprotectants, to which the IGF1-like activity of daucosterol contributes and it could be potentially developed as a medicine for ischemic stroke treatment. Moreover, daucosterol has neuroprotective activity, it has proliferation-enhancing activity of neural stem cells (NSCs), and it as an efficient and inexpensive growth factor alternative that could be potentially developed as a medicine for ischemic stroke treatment, can significantly reduce neuronal loss.
The study demonstrated that daucosterol works as an efficient and inexpensive growth factor alternative that could be used in clinical medicine and research applications.
Description
Daucosterol, alias: Citoside, β-Sitosterol β-D-glucoside, and the molecular formula is C35H6. The compound of the formula (description column) belongs to a carotene compound, which is present in mallow family plants, and figs and other plants also contain carotene. Daucosterol exhibits anti-tumor, anti-inflammatory and acaricidal activities, also moderate antibacterial activity against Bacillus subtilis and Staphylococcus aureus, and it has anti-cancer and apoptotic effects in human colon cancer cell line HCT-116.
Chemical Properties
White to off white powder
Uses
β-Sitosterol and β-sitosteryl-β-D-glucoside were isolated as analgesic constituents from the leaves of Mentha cordifolia Opiz.
Definition
ChEBI: A steroid saponin that is sitosterol attached to a beta-D-glucopyranosyl residue at position 3 via a glycosidic linkage. It has bee isolated from Panax japonicus var. major and Breynia fruti osa.
Synthesis
2280-44-6
83-46-5
474-58-8
β-sitosterol (124.4 g, 0.3 mol) and D-glucose (18.0 g, 0.1 mol) were dissolved in ethylbenzene (600 mL). Trimethylsilyl trifluoromethanesulfonate (TMSOTf, 8.9 g, 7.3 mL, 40 mmol) was slowly added to the reaction system at 80 °C and the reaction was continued at a constant temperature until thin-layer chromatography (TLC) detection showed that the D-glucose was almost completely consumed (about 15 h). Upon completion of the reaction, the reaction solution was concentrated and subsequently separated by silica gel column chromatography using dichloromethane as eluent (silica gel particle size 100-200 mesh). The separation was monitored by TLC until β-sitosterol was no longer detected in the eluate, and the corresponding eluate was collected and concentrated to give the recovered β-sitosterol (83.0 g, 0.2 mol). The elution was continued with ethyl acetate as eluent and monitored by TLC until the target product (2R,3R,4S,5S,6R)-2-((3S,8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3, 4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. Concentration of the eluate containing the target product gave a white solid product (47.3 g) in 82% yield and 97.8% purity as determined by high performance liquid chromatography (HPLC).
in vivo
Daucosterol (0.5-2.5 mg/kg, p.o., once per day for 7 days) significantly inhibits the H22 tumor growth in ICR mice inoculated with H22 hepatoma cells[1].
References
[1] Patent: CN104693266, 2018, B. Location in patent: Paragraph 0062-0064
ELEUTHEROSIDE A Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from ELEUTHEROSIDE A manufacturers
- Product
- ELEUTHEROSIDE A 474-58-8
- Price
- US $1.00-22.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100000KG
- Release date
- 2024-08-02
- Product
- Eleutheroside A 474-58-8
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥95%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-12-24
- Product
- ELEUTHEROSIDE A 474-58-8
- Price
- US $1.00/kg
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-12-24