ChemicalBook > CAS DataBase List > ELEUTHEROSIDE B1(RG)
ELEUTHEROSIDE B1(RG)
- Product Name
- ELEUTHEROSIDE B1(RG)
- CAS No.
- 16845-16-2
- Chemical Name
- ELEUTHEROSIDE B1(RG)
- Synonyms
- ELEUTHEROSIDE B1(RG);2H-1-Benzopyran-2-one,7-(a-D-glucopyranosyloxy)-6,8-dimethoxy-;2H-1-Benzopyran-2-one, 7-(α-D-glucopyranosyloxy)-6,8-dimethoxy-;6,8-Dimethoxy-7-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one;Eleutheroside B 1,Influenza Virus,anti-inflammatory,virus,host,Eleutheroside B1,anti-influenza,Eleutheroside B-1,Inhibitor,genes,biosynthesis,inhibit
- CBNumber
- CB4655037
- Molecular Formula
- C17H20O10
- Formula Weight
- 384.34
- MOL File
- 16845-16-2.mol
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ELEUTHEROSIDE B1(RG) Property
- Boiling point:
- 675.0±55.0 °C(Predicted)
- Density
- 1.524±0.06 g/cm3(Predicted)
- storage temp.
- 4°C, away from moisture and light
- pka
- 12.65±0.70(Predicted)
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ELEUTHEROSIDE B1(RG) Chemical Properties,Usage,Production
Chemical Properties
White crystalline powder, soluble in chloroform, derived from the dried rhizome of Acanthopanax senticosus.
Biological Activity
Eleutheroside B1, a coumarin compound, has broad-spectrum anti-human influenza virus (influenza virus) activity with IC50 values of 64-125μg/ml. It mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits mRNA expression of multiple chemokine genes and influenza virus nucleoprotein (NP) gene with low cytotoxicity. Has antiviral and anti-inflammatory activity.
in vitro
Eeutheroside B1 (100 μg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells.
RT-PCR
| Cell Line: | Virus-infected A549 cells |
| Concentration: | 100 μg/ml |
| Incubation Time: | 24 hours |
| Result: | The expression of host genes (MAN2A2, POLR2A) and virus genes (PA, PB1, PB2, HA) were decreased. |
ELEUTHEROSIDE B1(RG) Preparation Products And Raw materials
Raw materials
Preparation Products
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ELEUTHEROSIDE B1(RG) Suppliers
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View Lastest Price from ELEUTHEROSIDE B1(RG) manufacturers
Career Henan Chemical Co
- Product
- 2H-1-Benzopyran-2-one,7-(a-D-glucopyranosyloxy)-6,8-dimethoxy- 16845-16-2
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 20 tons
- Release date
- 2020-01-09
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