4-Hydroxy Cholesterol-d7

Product Name: 4-Hydroxy Cholesterol-d7
CAS No.: 1246302-80-6
Chemical Name: 4-Hydroxy Cholesterol-d7
Synonyms: 4-Hydroxy Cholesterol-d7;4β-Hydroxy Cholesterol-d7;cholest-5-ene-3,4-diol-d7;2H7]-4β-Hydroxycholesterol;4-beta-Hydroxy Cholesterol-d7;CHOLEST-5-ENE-3,4-DIOL-D7;4-HYDROXYCHOLESTEROL-D7;(3S,4R,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6,7,7,7-tetradeuterio-6-(trideuteriomethyl)heptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,4-diol
CBNumber: CB72487154
Molecular Formula: C27H46O2
Formula Weight: 402.65294
MOL File: 1246302-80-6.mol

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4-Hydroxy Cholesterol-d7 Property

Melting point:: 154-159°C
storage temp.: -20°C
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated)
form: Solid
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 25971
Product name: 4β-hydroxy Cholesterol-d7
Purity: ≥99% deuterated forms (d1-d7)
Packaging: 500μg
Price: $189
Updated: 2024/03/01

Cayman Chemical

Product number: 25971
Product name: 4β-hydroxy Cholesterol-d7
Purity: ≥99% deuterated forms (d1-d7)
Packaging: 1mg
Price: $359
Updated: 2024/03/01

TRC

Product number: H917982
Product name: 4β-HydroxyCholesterol-d7
Packaging: 1mg
Price: $205
Updated: 2021/12/16

Usbiological

Product number: 013561
Product name: 4β-Hydroxy Cholesterol-d7
Packaging: 1mg
Price: $496
Updated: 2021/12/16

AK Scientific

Product number: 0465CK
Product name: Cholest-5-en-3beta,4beta-diol(d7)
Packaging: 1mg
Price: $498
Updated: 2021/12/16

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4-Hydroxy Cholesterol-d7 Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

4β-Hydroxy Cholesterol-d7 is a labelled metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.

Uses

4β-hydroxycholesterol-d7 has been used:

as an internal standard to spike plasma samples ultra-high-pressure liquid,chromatography–tandem mass spectrometry (UHPLC-MS/MS) analysis
to spike serum samples for mass spectrometry measurements
as an internal standard for the quantification of human colon biopsies samples using HPLC-MS

General Description

4β-hydroxycholesterol (4β-HC) is a catabolic product of cholesterol metabolism mediated by the enzyme cytochrome P450 family 3 subfamily A member 4 (CYP3A4). 4β-hydroxycholesterol-d7 is the deuterated form of 4β-hydroxycholesterol.

Biochem/physiol Actions

4β-hydroxycholesterol (4β-HC) may function as a liver X receptor ligand. The levels of 4β-HC are elevated in dextran sulfate induced colitis along with other oxysterols and it may promote colon inflammation.

4-Hydroxy Cholesterol-d7 Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Hydroxy Cholesterol-d7 Suppliers

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1246302-80-6, 4-Hydroxy Cholesterol-d7Related Search:

4-Hydroxy Cholesterol-d7

CHOLEST-5-ENE-3,4-DIOL-D7;4-HYDROXYCHOLESTEROL-D7

(3S,4R,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6,7,7,7-tetradeuterio-6-(trideuteriomethyl)heptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,4-diol

4-beta-Hydroxy Cholesterol-d7

cholest-5-ene-3,4-diol-d7

4β-Hydroxy Cholesterol-d7

2H7]-4β-Hydroxycholesterol

1246302-80-6

Intermediates & Fine Chemicals

Isotope Labelled Compounds

Metabolites & Impurities

Pharmaceuticals

Steroids

Isotope Labelled Compounds, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids