ChemicalBook > CAS DataBase List > Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate

Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate

Product Name
Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate
CAS No.
1188477-11-3
Chemical Name
Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate
Synonyms
Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate;tert-butyl N-[(5-bromo-2-pyridyl)methyl]carbamate;Carbamic acid, N-[(5-bromo-2-pyridinyl)methyl]-, 1,1-dimethylethyl ester
CBNumber
CB72499212
Molecular Formula
C11H15BrN2O2
Formula Weight
287.15
MOL File
1188477-11-3.mol
More
Less

Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate Property

Boiling point:
372.4±32.0 °C(Predicted)
Density 
1.367±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
11.14±0.46(Predicted)
Appearance
White to light yellow Solid
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
B129575
Product name
tert-Butyl((5-Bromopyridin-2-yl)methyl)carbamate
Packaging
50mg
Price
$45
Updated
2021/12/16
Activate Scientific
Product number
AS29036
Product name
2-(Boc-aminomethyl)-5-bromopyridine
Purity
97+%
Packaging
250mg
Price
$130
Updated
2021/12/16
Activate Scientific
Product number
AS29036
Product name
2-(Boc-aminomethyl)-5-bromopyridine
Purity
97+%
Packaging
1g
Price
$259
Updated
2021/12/16
Matrix Scientific
Product number
073840
Product name
(5-Bromopyridin-2-ylmethyl)carbamic acidtert-butyl ester
Purity
95+%
Packaging
250mg
Price
$416
Updated
2021/12/16
AK Scientific
Product number
X9325
Product name
(5-Bromopyridin-2-ylmethyl)carbamicacidtert-butylester
Packaging
5g
Price
$531
Updated
2021/12/16
More
Less

Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate Chemical Properties,Usage,Production

Synthesis

24424-99-5

97483-77-7

1188477-11-3

GENERAL STEPS: To a solution of 5-bromo-2-cyanopyridine (3.0 g, 16.4 mmol) in methanol (60 mL) was sequentially added di-tert-butyl dicarbonate (7.2 g, 32.8 mmol) and nickel chloride hexahydrate (0.33 g, 1.64 mmol). The reaction mixture was cooled to 0 °C, followed by the addition of sodium borohydride (4.3 g, 0.115 mol) in batches over a period of 2 hours. The reaction mixture was continued to be stirred at 15 °C for 1 h, after which it was poured into ice water (200 g) and extracted with ethyl acetate. The organic layers were combined, washed with saturated brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by fast column chromatography to afford the target product tert-butyl (5-bromopyridin-2-ylmethyl)carbamate (2.2 g, 47% yield) as a yellow solid. m/z 287,289 ([M+H]+) by LC-MS.

References

[1] Patent: WO2016/112088, 2016, A1. Location in patent: Paragraph 0660
[2] Patent: US2013/237502, 2013, A1. Location in patent: Paragraph 0367
[3] Patent: WO2018/42342, 2018, A1. Location in patent: Page/Page column 53

Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate Suppliers

China 63 India 1 United States 7 Global 71
Tetranov Biopharm
Tel
13526569071
Email
sales@leadmedpharm.com
Country
China
ProdList
7892
Advantage
64
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Shanghai Litong Chemical Technology Co.,Ltd.
Tel
13598610367 0373-7129549
Fax
0373-8369699
Email
2468833170@qq.com
Country
China
ProdList
932
Advantage
58
CEG Chemical Science&Technology Co., Ltd.
Tel
Mobile:13665161512
Fax
+86-510-68873513
Country
China
ProdList
1785
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Nantong MYBio-pharm. Co., Ltd.
Tel
0513-85921823 18662920231
Fax
86-513-85012876
Email
sales@ntminyanmedical.com
Country
China
ProdList
4107
Advantage
58
Tianjin Anhao Biological Technology Co., Ltd.
Tel
Email
sales@ahpharmatech.com
Country
China
ProdList
5734
Advantage
55
JW & Y Pharmlab Co., Ltd.
Tel
021-64340559 13651849907;
Fax
021- 64345308
Email
xinyu_shi@jwypharmlab.com.cn
Country
China
ProdList
12000
Advantage
58
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7992
Advantage
55
Shanghai TuZhi Chemical Co., Ltd.
Tel
19542790274
Fax
QQ1456295541
Email
2119559397@qq.com
Country
China
ProdList
753
Advantage
50
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
8011
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai Huaxing Biological Technology Co., Ltd.
Tel
18621295758
Fax
-QQ:1449085402
Email
1449085402@qq.com
Country
China
ProdList
1724
Advantage
55
Hangzhou Molcore Biopharmatech Co.,Ltd
Tel
400-711-5280 86-571-81025280
Fax
86-571-85806285
Email
sales@molcore.com
Country
China
ProdList
9967
Advantage
58
Biokitchen
Tel
021-021-021-31663258 13795219287
Fax
021-31663258
Email
donghuanwen@126.com
Country
China
ProdList
8816
Advantage
58
LinkChem Technology Co., Ltd.
Tel
021-58950110 13124863828
Fax
021-20922272
Email
sales@linkchem.cn
Country
China
ProdList
2998
Advantage
58
Sichuan BaiPeng Biotechnology Co., Ltd.
Tel
028-65791793 18140026355
Fax
QQ568470422
Email
568470422@qq.com
Country
China
ProdList
9997
Advantage
58
Aikon International Limited
Tel
025-58851090 15955137747
Fax
(6)02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15949
Advantage
58
Shanghai WangFa Chemical Technology Co., Ltd.
Tel
13918479294
Fax
-
Email
xiebenfa@163.com
Country
China
ProdList
4087
Advantage
58
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 13482353728
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
9713
Advantage
58
Jinan chemkey pharmaceutical Co., Ltd.
Tel
15610156652
Email
baimingshi@163.com
Country
China
ProdList
981
Advantage
58
Shaanxi Yikunte Pharmaceutical Technology Co., Ltd.
Tel
18049260030 18049260030
Email
380381031@qq.com
Country
China
ProdList
500
Advantage
58
Shanghai SPAR pharmaceutical technology co., LTD
Tel
021-000000 13917643586;
Email
admin@jingshipharmatech.com
Country
China
ProdList
9857
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Cool Pharm, Ltd
Tel
021-58581007 18019463053
Fax
021-50966098
Email
sales@coolpharm.com
Country
China
ProdList
12878
Advantage
58
Shanghai zhigan biotechnology co., LTD
Tel
Email
zhiqianbio@126.com
Country
China
ProdList
19778
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
HaBo Hong Kong Co., Limited.
Tel
+86-25-18512596065
Email
info@habotech.com
Country
CHINA
ProdList
933
Advantage
58
Baimei Jihua (Henan) Pharmaceutical Technology Co., Ltd
Tel
037188900765 18037465274
Fax
QQ3430974218
Email
enyawanglei@sina.cn
Country
China
ProdList
13965
Advantage
58
Jinan ponder chemical co. LTD
Tel
0531-0000
Email
thinklifescience@163.com
Country
China
ProdList
19689
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29798
Advantage
58
Nantong puyue biomedical Co., Ltd
Tel
0513-0513-0513-89158300 18014392889
Fax
0513-89158198
Email
sales@puyerbiopharma.com
Country
China
ProdList
4956
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
Shanghai Ruipu Medical Technology Co., Ltd
Tel
15895968936
Fax
qq 1018762393
Email
1018762393@qq.com
Country
China
ProdList
9999
Advantage
58
Shanghai Hanlin biology science and technology co., ltd
Tel
183-0212-4410 18302124410
Email
Djt18302124410@163.com
Country
China
ProdList
3000
Advantage
58
Hubei Co-prosperity Medicine Technonlogy Co., Ltd
Tel
2383948258 19172820304
Email
2383948258@qq.com
Country
China
ProdList
12987
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
40000
Advantage
58
Bide Pharmatech Ltd.
Tel
400-6005915
Email
sales@picasso-e.com
Country
China
ProdList
39653
Advantage
58
Beijing InnoChem Science & Technology Co., Ltd.
Tel
15652467323
Email
sales@inno-chem.com.cn
Country
China
ProdList
8293
Advantage
58
Jiaxing Deyi Chemical Co., Ltd
Tel
0573-85866609 13588473046
Email
824930988@qq.com
Country
China
ProdList
7865
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
18621169109
Email
market03@meryer.com
Country
China
ProdList
27987
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50464
Advantage
58
Shanghai Jieshikai Biotechnology Co. , Ltd.
Tel
021-57520305 13795461237
Email
zhuruyan@jskchem.com
Country
China
ProdList
49234
Advantage
58
PharmaBlock Sciences (Nanjing), Inc.
Tel
4000255188
Email
marketing@pharmablock.com
Country
China
ProdList
9126
Advantage
58
Zhuhai Aobokai Biomedical Technology Co., Ltd.
Tel
400-0628126 18736790110;
Email
sales-team@aobchem.com.cn
Country
China
ProdList
50000
Advantage
58
https://hanhongsci.com/
Tel
021-54306202 18917919676
Email
info@hanhongsci.com
Country
China
ProdList
29995
Advantage
58
More
Less

View Lastest Price from Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate manufacturers

Career Henan Chemical Co
Product
Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate 1188477-11-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-02

1188477-11-3, Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamateRelated Search:

TERT-BUTYL [(6-CHLOROPYRIDIN-3-YL)METHYL]CARBAMATE

  • Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate
  • Carbamic acid, N-[(5-bromo-2-pyridinyl)methyl]-, 1,1-dimethylethyl ester
  • tert-butyl N-[(5-bromo-2-pyridyl)methyl]carbamate
  • 1188477-11-3