ChemicalBook > CAS DataBase List > 2,5-Difluoro-4-iodopyridine

2,5-Difluoro-4-iodopyridine

Product Name
2,5-Difluoro-4-iodopyridine
CAS No.
1017793-20-2
Chemical Name
2,5-Difluoro-4-iodopyridine
Synonyms
2,5-Difluoro-4-iodopyridine;Pyridine, 2,5-difluoro-4-iodo-;2,5-Difluoro-4-iodopyridine ISO 9001：2015 REACH
CBNumber
CB72500701
Molecular Formula
C5H2F2IN
Formula Weight
240.98
MOL File
1017793-20-2.mol
More
Less

2,5-Difluoro-4-iodopyridine Property

Boiling point:
209.7±35.0 °C(Predicted)
Density 
2.129±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
-4.24±0.18(Predicted)
Appearance
Light yellow to light brown Solid
More
Less

Safety

HazardClass 
IRRITANT
HS Code 
2933399990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

TRC
Product number
D451928
Product name
2,5-Difluoro-4-iodopyridine
Packaging
100mg
Price
$75
Updated
2021/12/16
ChemScene
Product number
CS-0005562
Product name
2,5-Difluoro-4-iodopyridine
Purity
98.51%
Packaging
5g
Price
$82
Updated
2021/12/16
Apolloscientific
Product number
PC53341
Product name
2,5-Difluoro-4-iodopyridine
Packaging
1g
Price
$85
Updated
2021/12/16
Matrix Scientific
Product number
059330
Product name
2,5-Difluoro-4-iodopyridine
Purity
97%
Packaging
5g
Price
$89
Updated
2021/12/16
AK Scientific
Product number
Z6412
Product name
2,5-Difluoro-4-iodopyridine
Packaging
1g
Price
$89
Updated
2021/12/16
More
Less

2,5-Difluoro-4-iodopyridine Chemical Properties,Usage,Production

Synthesis

84476-99-3

1017793-20-2

Preparative Example 2: Synthesis of 2,5-difluoro-4-iodopyridine Diisopropylamine (17 mL, 122 mmol) was added to tetrahydrofuran (220 mL) under nitrogen protection, and the mixture was cooled to -20 °C. Slowly n-butyllithium (49 mL, 122.5 mmol) was added dropwise, and after the drop was completed, the reaction mixture was stirred at -20 °C for 0.5 h and subsequently cooled to -78 °C. At this temperature, a tetrahydrofuran (30 mL) solution of 2,5-difluoropyridine (13.3 g, 115 mmol) was slowly added and the reaction temperature was maintained at -78 °C with stirring for 4 hours. Iodine (32 g, 126 mmol) was dissolved in tetrahydrofuran (100 mL) and slowly added to the above reaction solution and continued to stir at -78 °C for 1 hour. After the reaction was completed, water (10 mL) and tetrahydrofuran (30 mL) were added and slowly warmed to room temperature. The reaction was quenched by the addition of saturated sodium thiosulfate solution. The organic phase was separated and the aqueous phase was extracted with ethyl acetate (3 x 100 mL). The organic phases were combined, dried with anhydrous sodium sulfate, filtered and the filtrate was concentrated. Purification by silica gel column chromatography (eluent: petroleum ether/ethyl acetate=50:1) afforded the target product 2,5-difluoro-4-iodopyridine (13.5 g, 48% yield).

References

[1] Patent: CN104910137, 2017, B. Location in patent: Paragraph 0213-0216
[2] Patent: EP3091008, 2016, A1. Location in patent: Paragraph 0167; 0168
[3] Patent: WO2011/73845, 2011, A1. Location in patent: Page/Page column 116-117

2,5-Difluoro-4-iodopyridine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2,5-Difluoro-4-iodopyridine Suppliers

China 114 Germany 2 India 1 United Kingdom 1 United States 11 Global 129
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2806
Advantage
65
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16075
Advantage
64
Jinan Trio PharmaTech Co., Ltd.
Tel
0531-88811783
Fax
+86 (531) 55696010 QQ 1762738062
Email
sales@trio-pharmatech.com
Country
China
ProdList
1856
Advantage
62
Nanjing Lynsci Chemical Co., Ltd
Tel
+86-025-83208253 +86-13851694729
Fax
0086-25-83208253
Email
layefe@163.com
Country
China
ProdList
231
Advantage
62
Tianjin Jinyuda Chemical Co., Ltd.
Tel
022-58013646 13011382049
Fax
022-23854368
Email
sales@jinyudachem.com
Country
China
ProdList
1930
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
150-2103-5486 18017383231
Fax
qq：2817624287
Email
983544897@qq.com
Country
China
ProdList
9342
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Hebei Summedchem Co.,Ltd
Tel
0319-5801333-8008 15630992918
Email
sales@summedchem.com
Country
China
ProdList
965
Advantage
58
Tianjin Chempharmatech Co.,Ltd.
Tel
022-66211079 13212288319
Fax
qq1405432731
Email
sales@chempharmatech.com
Country
China
ProdList
918
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9979
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
14912
Advantage
59
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5674
Advantage
50
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Xi'an NewProChem Co.,Ltd.
Tel
15332490153
Fax
QQ 2725398181
Email
newprochem@126.com
Country
China
ProdList
991
Advantage
55
Atop Bio-Tech (Tianjin) Co., Ltd. (Atop)
Tel
022-66200236 18622210341
Fax
+86-022-66200236
Email
sales@atop-biotech.com
Country
China
ProdList
295
Advantage
60
NovoChemy Ltd.
Tel
86-(0)21-31261262 373522135
Fax
86-(0)21-33250524
Email
sales@novochemy.com
Country
China
ProdList
6498
Advantage
58
Fuxin Fengcheng Chemical Technology Development Co., Ltd.
Tel
0418-2868000 13464847801
Fax
+86-418-3810066
Email
jingxuan.lu@fcmeditech.com
Country
China
ProdList
342
Advantage
55
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
3495
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
ChengDu TongChuangYuan Pharmaceutical Co.Ltd
Tel
028-83379370 13880556291
Fax
028-87747383
Email
tcy@tcypharm.com
Country
China
ProdList
7218
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10110
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2886750 13927877953
Fax
0751-2886750
Email
3005811397@qq.com
Country
China
ProdList
13305
Advantage
58
Shanghai Huaxing Biological Technology Co., Ltd.
Tel
18621295758
Fax
-QQ:1449085402
Email
1449085402@qq.com
Country
China
ProdList
1817
Advantage
55
Shanghai CR Corporation Limited
Tel
13062833949; 4006653949 4006653949
Fax
QQ: 2136646215
Email
fred.wen@crcorporation.cn
Country
China
ProdList
9757
Advantage
58
Nanijing m&m biotechnology Co. ,Ltd.
Tel
025-87782433 18021532344
Fax
025-87782433
Email
1345332203@qq.com
Country
China
ProdList
4134
Advantage
58
Shanghai Zhen Li Biological Technology Co., Ltd
Tel
021-16621358918; 18516310516
Fax
13045646768
Email
zhenlipharma888@163.com
Country
China
ProdList
19035
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
Aikon International Limited
Tel
025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
16027
Advantage
58
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17987
Advantage
58
Hebei Huaxing Chemical Co., Ltd
Tel
0319-6931777 13930968617
Fax
+86-319-6931577
Email
630669494@qq.com
Country
China
ProdList
1021
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
inan new medical technology co., LTD
Tel
0531-; 18954137585
Fax
1939458511
Email
1939458511@qq.com
Country
China
ProdList
294
Advantage
58
Shanghai SPAR pharmaceutical technology co., LTD
Tel
021-000000 13917643586;
Email
admin@jingshipharmatech.com
Country
China
ProdList
9856
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
WEIFANG CYANOCHEM CO; LTD.
Tel
0571-85220831 13188860031
Fax
+86 571 85220831
Email
476521632@qq.com
Country
China
ProdList
297
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2815688 13927872512
Fax
0751-8963795
Email
3007421951@qq.com
Country
China
ProdList
9939
Advantage
58
Shanghai zhigan biotechnology co., LTD
Tel
Email
zhiqianbio@126.com
Country
China
ProdList
19778
Advantage
58
Jinan Carbotang Biotech Co.,Ltd.
Tel
+8615866703830
Email
figo.gao@foxmail.com
Country
China
ProdList
8497
Advantage
58
Henan Alpha Chemical Co., Ltd.
Tel
0371-55055611 18137792234
Fax
QQ：3002694073
Email
3002694073@qq.com
Country
China
ProdList
9987
Advantage
58
Allfluoro pharmaceutical co. ltd.
Tel
+86-400-0216110 +86-15958047586
Fax
0086-21-33275002
Email
sales@allfluoro.com
Country
China
ProdList
11385
Advantage
58
ANHUI WITOP BIOTECH CO., LTD
Tel
+8615255079626
Email
eric@witopchemical.com
Country
China
ProdList
23541
Advantage
58
More
Less

View Lastest Price from 2,5-Difluoro-4-iodopyridine manufacturers

Dideu Industries Group Limited
Product
2,5-Difluoro-4-iodopyridine 1017793-20-2
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-09-01
Career Henan Chemical Co
Product
2,5-Difluoro-4-iodopyridine 1017793-20-2
Price
US $6.60/KG
Min. Order
500g
Purity
98%
Supply Ability
1KG, 50KG, 100KG
Release date
2019-12-25

1017793-20-2, 2,5-Difluoro-4-iodopyridineRelated Search:

Propidium iodide 4-IODO-PYRIDIN-3-OL

  • 2,5-Difluoro-4-iodopyridine
  • Pyridine, 2,5-difluoro-4-iodo-
  • 2,5-Difluoro-4-iodopyridine ISO 9001：2015 REACH
  • 1017793-20-2