ChemicalBook > CAS DataBase List > 2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol

2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol

Product Name
2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol
CAS No.
63676-22-2
Chemical Name
2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol
Synonyms
Raloxifene Impurity 4;Raloxifene InterMediate;Estrogen receptor modulator 1;BTC (Estrogen receptor modulator 1);2-(4-Hydroxyphenyl)benzothiophene-6-ol;2-(4-Hydroxyphenyl)benzo[b]thiophen-6-ol;2-(4-hydroxyphenyl)-1-benzothiophen-6-ol;2-(4-hydroxyphenyl)-1-benzothiophene-6-ol;2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol;Benzo[b]thiophene-6-ol, 2-(4-hydroxyphenyl)-
CBNumber
CB72509951
Molecular Formula
C14H10O2S
Formula Weight
242.29
MOL File
63676-22-2.mol
More
Less

2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol Property

Melting point:
295 °C(dec.)
Boiling point:
477.0±30.0 °C(Predicted)
Density 
1.383
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
9.32±0.15(Predicted)
color 
Pale Grey
More
Less

Safety

HS Code 
2934.99.4400
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1376
Product name
BTC
Purity
≥95% (HPLC)
Packaging
10MG
Price
$102
Updated
2022/05/15
TCI Chemical
Product number
H1628
Product name
2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol
Purity
>98.0%(GC)
Packaging
50mg
Price
$117
Updated
2025/07/31
TCI Chemical
Product number
H1628
Product name
2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol
Purity
>98.0%(GC)
Packaging
200mg
Price
$346
Updated
2025/07/31
TRC
Product number
H949315
Product name
2-(4-Hydroxyphenyl)benzo[b]thiophen-6-ol
Packaging
250mg
Price
$300
Updated
2021/12/16
TRC
Product number
H949315
Product name
2-(4-Hydroxyphenyl)benzo[b]thiophen-6-ol
Packaging
1g
Price
$1040
Updated
2021/12/16
More
Less

2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol Chemical Properties,Usage,Production

Uses

2-(4-Hydroxyphenyl)benzo[b]thiophen-6-ol is used in the synthesis of Raloxifene (R100000) an estrogen receptor modulator.

in vivo

Estrogen receptor modulator 1 (1.5 mg/animal; p.o. ; daily for 2 weeks) results in regression of T47D:A18/PKCα tumors[2].

Animal Model:4-6 week old athymic mice (Harlan-Sprague-Dawley)[2]
Dosage:1.5 mg/animal
Administration:p.o. ; daily for 2 weeks
Result:Significantly reduced tumor volume.

2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol Suppliers

Americas 1 China 99 Europe 1 India 17 Japan 1 United Kingdom 1 United States 11 Global 131
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14332
Advantage
58
Cato Research Chemicals Inc.
Tel
+86-020-81960175-877 4000-868-328
Email
tianwen.zhan@cato-chem.com
Country
United States
ProdList
10404
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
NE Scientific
Tel
--
Fax
--
Country
United States
ProdList
5030
Advantage
55
More
Less

View Lastest Price from 2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol manufacturers

Jinan Ruitong Biotech Co., Ltd.
Product
2-(4-hydroxyphenyl)benzo[b]thiophen-6-ol 63676-22-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1
Release date
2025-08-26
Career Henan Chemical Co
Product
2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol 63676-22-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-05-24

63676-22-2, 2-(4-Hydroxyphenyl)benzo[b]thiophene-6-olRelated Search:

[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-7-yl] Raloxifene Impurity 21 Raloxifene N-Oxide 7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene (Raloxifene Impurity) Raloxifene Impurity 1 Raloxifene 6'-glucuronide Raloxifene Impurity 18 RALOXIFENE-D4, HYDROCHLORIDE Raloxifene 4'-glucuronide [6-hydroxy-7-[6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)benzoyl]-1-benzothiophen-7-yl]-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone Raloxifene Impurity 19 Raloxifene-4'-glucuronide_d4 Raloxifene Impurity 14 4-(3-(Piperidin-1-yl)propoxy)benzoic acid 2-(4-METHOXY PHENYL)BENZOTHIOPHENE-6-OL Raloxifene Impurity 1-(2-Chloroethyl)piperidine hydrochloride 2-[4-[(Methylsulfonyl)oxy]phenyl]-Benzo[b]thiophene-6-ol 6-Methanesulfonate

  • 2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol
  • 2-(4-hydroxyphenyl)-1-benzothiophene-6-ol
  • Raloxifene InterMediate
  • 2-(4-Hydroxyphenyl)benzo[b]thiophen-6-ol
  • 6-Hydroxy-2-(4-Hydroxyphenyl)Benzo[B]Thiophene
  • 2-(4-hydroxyphenyl)-1-benzothiophen-6-ol
  • Raloxifene Impurity 4
  • 2-(4-Hydroxyphenyl)benzothiophene-6-ol
  • Estrogen receptor modulator 1
  • Benzo[b]thiophene-6-ol, 2-(4-hydroxyphenyl)-
  • BTC (Estrogen receptor modulator 1)
  • Estrogen Receptor/ERR,MCF-7:5C,Estrogen receptor modulator 1,cancer,selective,Estrogen receptor modulator1,breast,Estrogen receptor modulator-1,cells,tumor,athymic,mice,inhibit,Inhibitor
  • Estrogen receptor modulator 1, 10 mM in DMSO
  • 63676-22-2