2-PHENYLINDOLE-3-CARBOXALDEHYDE Property

Melting point:

249-253 °C (lit.)

Boiling point:

462.9±33.0 °C(Predicted)

Density 

1.237±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

form 

powder to crystal

pka

15.30±0.30(Predicted)

color 

White to Brown

Sensitive 

Air Sensitive

CAS DataBase Reference

25365-71-3(CAS DataBase Reference)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29339900

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2-PHENYLINDOLE-3-CARBOXALDEHYDE Chemical Properties,Usage,Production

Uses

Reactant for preparation of:

• Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
• Pyrimidinones via Biginelli reaction as antimicrobial agents
• [(phenyl)pyrazolyl]indole derivatives as antiinflammatory agents and analgesics
• Indole thiophene chalcones via Claisen-Schmidt condensation as antimicrobial and antioxidant agents
• Benzofuranone attached indole derivatives as PI3K inhibitors
• Ionone-based chalcones as novel antiandrogens
• Oxazolylindoles as antiinflammatory agents for edema