ChemicalBook > CAS DataBase List > (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one

Product Name
(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
CAS No.
123367-26-0
Chemical Name
(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
Synonyms
Imatinib impurity J;Irutinib Impurity A;(E)-3-(dimethylamino);Imatinib EP impuritiesA;Imatinib Mesilate Impurity A;Imatinib Mesilate EP Impurity A;Nilotinib Impurity 16 (Imatinib EP Impurity A);Imatinib EP Impurity A (Nilotinib Impurity 16);(E)-3-(Dimethylamino)-1-(3-pyridyl)-2-propen-1-one;(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
CBNumber
CB72516261
Molecular Formula
C10H12N2O
Formula Weight
176.22
MOL File
123367-26-0.mol
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(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Property

Melting point:
113℃
Boiling point:
281℃
Density 
1.070
Flash point:
124℃
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
4.74±0.70(Predicted)
color 
Dark Brown to Very Dark Brown
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
D462115
Product name
(2E)​-​3-​(Dimethylamino)​-​1-​(3-​pyridyl)​prop-​2-​en-​1-​one
Packaging
250mg
Price
$50
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-1-DW
Product name
(2E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
Purity
98.0%
Packaging
250mg
Price
$65
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-1-DW
Product name
(2E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
Purity
98.0%
Packaging
1g
Price
$95
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-1-DW
Product name
(2E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
Purity
98.0%
Packaging
5G
Price
$295
Updated
2021/12/16
Alichem
Product number
123367260
Product name
(E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
Packaging
500g
Price
$296.8
Updated
2021/12/16
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(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Chemical Properties,Usage,Production

Description

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one is a pharmaceutical intermediate used as an intermediate of nilotinib, a targeted anticancer drug for the treatment of chronic myeloid leukaemia (CML).

Uses

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one acts as a reagent for the synthesis of oxindole-linked indolyl-pyrimidine derivatives which are potential cytotoxic agents.

Solubility in organics

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one is soluble in chloroform and dichloromethane.

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

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(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Suppliers

Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
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59
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
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65
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
4969
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NCE Biomedical Co.,Ltd.
Tel
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax
+86-27-87599188
Country
China
ProdList
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Moltt Biocem Co., Ltd.
Tel
+86-21-38682181 15900741819
Fax
+86-21-38682181
Country
China
ProdList
282
Advantage
55
Alputon Inc.
Tel
021-60753308-14013
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021-60753309
Country
China
ProdList
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Taizhou Tongxin Bio-Tech Co., Ltd
Tel
0523-18601685-898 18652728585
Email
sales@allyrise.com
Country
China
ProdList
2741
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Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
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Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9636
Advantage
58
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-58362220 15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7730
Advantage
55
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View Lastest Price from (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one manufacturers

Career Henan Chemical Co
Product
(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one 123367-26-0
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2019-12-25

123367-26-0, (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-oneRelated Search:


  • (2E)-3-(DiMethylaMino)-1-(pyridin-3-yl)prop-2-en-1-one
  • (2E)-3-(DiMethylaMino)-1-(3-pyridyl)prop-2-en-1-one (IMpurity of Nilotinib)
  • (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
  • (E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
  • Imatinib EP Impurity A (Nilotinib Impurity 16)
  • Nilotinib Impurity 16 (Imatinib EP Impurity A)
  • Imatinib impurity 14/(E)-3-(dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
  • (E)-3-(dimethylamino)
  • Nilotinib IMpurity ((2E)-3-(DiMethylaMino)-1-(3-pyridyl)prop-2-en-1-one)
  • Irutinib Impurity A
  • Imatinib impurity J
  • 2-Propen-1-one, 3-(dimethylamino)-1-(3-pyridinyl)-, (2E)-
  • (E)-3-(Dimethylamino)-1-(3-pyridyl)-2-propen-1-one
  • Imatinib EP impuritiesA
  • Imatinib Mesilate EP Impurity A
  • Imatinib Mesilate Impurity A
  • (2E)-3-(Dimethylamino)-1-(3-Pyridyl)prtop-2-en-1-one
  • 123367-26-0