Ibrutinib Dimer Impurity

Product Name: Ibrutinib Dimer Impurity
CAS No.: 2031255-23-7
Chemical Name: Ibrutinib Dimer Impurity
Synonyms: Impurity API-IM11;Irotinib impurity E;Ibrutinib Dimer Imp;Ibrutinib iMpurity MDAEJ;Ibrutinib Dimer Impurity;1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]-3-[[(1R)-3-(4-phenoxyphenyl)-1-(1-prop-2-enoyl-3-piperidyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]propan-1-one;2-Propen-1-one, 1-[(3R)-3-[4-[[3-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-3-oxopropyl]amino]-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-;1-((R)-3-(4-((3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)amino)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one (Ibrutinib Impurity)
CBNumber: CB14796180
Molecular Formula: C50H48N12O4
Formula Weight: 880.99
MOL File: 2031255-23-7.mol

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Ibrutinib Dimer Impurity Property

Density: 1.40±0.1 g/cm3(Predicted)
solubility: Chloroform (Slightly), DMSO (Slightly)
pka: 4.09±0.30(Predicted)
form: Solid
color: White to Off-White
Stability:: Light Sensitive

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: I124985
Product name: IbrutinibDimer(~90%)
Packaging: 25mg
Price: $1100
Updated: 2021/12/16

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Ibrutinib Dimer Impurity Chemical Properties,Usage,Production

Uses

Ibrutinib Dimer Impurity is a dimer impurity of Ibrutinib (I124970), a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.

Ibrutinib Dimer Impurity Preparation Products And Raw materials

Raw materials

Preparation Products

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Ibrutinib Dimer Impurity Suppliers

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2031255-23-7, Ibrutinib Dimer ImpurityRelated Search:

Btk inhibitor 1 (R enantioMer hydrochloride) Ibrutinib Impurity 21 Ibrutinib Impurity 10 (S)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl) (S)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Ibrutinib Impurity 14 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine N-BOC-2-HYDROXYPIPERIDINE 2-Propen-1-one, 1-[4-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-1-piperidinyl]- 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine Ibrutinib Impurity 37 Ibrutinib Impurity 18 Ibrutinib Impurity 6 Ibrutinib Impurity 3 (S)-1-Boc-3-hydroxypiperidine Ibrutinib Impurity 30 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Acrylic anhydride

Ibrutinib Dimer Imp

2-Propen-1-one, 1-[(3R)-3-[4-[[3-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-3-oxopropyl]amino]-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-

Ibrutinib iMpurity MDAEJ

1-((R)-3-(4-((3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)amino)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one (Ibrutinib Impurity)

1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]-3-[[(1R)-3-(4-phenoxyphenyl)-1-(1-prop-2-enoyl-3-piperidyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]propan-1-one

Ibrutinib Dimer Impurity

Irotinib impurity E

Impurity API-IM11

2031255-23-7