3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine
- Product Name
- 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine
- CAS No.
- 1022150-12-4
- Chemical Name
- 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine
- Synonyms
- (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine;ibrutinib N-1;3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride;Ilutinib impurity 18;Ibrutinib Impurity 18;4-d]pyriMidin-4-ylaMine;Ibrutinib intermediate 1;Ibrutinib intermeidate N-1;Btk inhibitor 1 (R enantioMer)
- CBNumber
- CB52623905
- Molecular Formula
- C22H22N6O
- Formula Weight
- 386.45
- MOL File
- 1022150-12-4.mol
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Property
- Melting point:
- 133-136oC
- Boiling point:
- 626.3±55.0 °C(Predicted)
- Density
- 1.39±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 9.00±0.10(Predicted)
- form
- Solid
- color
- White to Pale Yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- P318770
- Product name
- (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- Packaging
- 10g
- Price
- $845
- Updated
- 2021/12/16
- Product number
- P318770
- Product name
- (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- Packaging
- 5g
- Price
- $545
- Updated
- 2021/12/16
- Product number
- 132822
- Product name
- 3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- Purity
- 97%
- Packaging
- 5g
- Price
- $864
- Updated
- 2021/12/16
- Product number
- CHM0292889
- Product name
- 3-(4-PHENOXY-PHENYL)-1-PIPERIDIN-3-YL-1H-PYRAZOLO-[3,4-D]PYRIMIDIN-4-YLAMINE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1246.25
- Updated
- 2021/12/16
- Product number
- CS-2435
- Product name
- IBT6A
- Purity
- 99.47%
- Packaging
- 50mg
- Price
- $1800
- Updated
- 2021/12/16
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Chemical Properties,Usage,Production
Description
IBT6A is a Btk kinase inhibitor. This compound is a precurser for the manufacture of ibrutinib.
Uses
(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is an intermediate used to prepare pyrazolo-pyrimidine compounds as inhibitors of Bruton''s tyrosine kinase. It is also an intermediate for Ibrutinib (I124970) derivatives.
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Preparation Products And Raw materials
Raw materials
Preparation Products
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Suppliers
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View Lastest Price from 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine manufacturers
- Product
- (R)-3-(4-phenoxyphenyl)-1-(pi-peridin-3-yl)-1H-pyrazolo-[3,4-d]pyrimidin-4-amine 1022150-12-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1 ton
- Release date
- 2023-12-28
- Product
- Btk inhibitor 1 R enantiomer 1022150-12-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2024-11-13
- Product
- 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine 1022150-12-4
- Price
- US $20.00-10.00/kg
- Min. Order
- 25kg
- Purity
- 99%
- Supply Ability
- 200ton
- Release date
- 2023-03-13