Prednicarbate

Product Name: Prednicarbate
CAS No.: 73771-04-7
Chemical Name: Prednicarbate
Synonyms: Regemt;Regenit;HOE-777;Dermatop;Prednitop;S-77-0777;PREDNICARBATE;UNII-V901LV1K7D;Prednicarbate CRS;Prednicarbate, >=98%
CBNumber: CB5342987
Molecular Formula: C27H36O8
Formula Weight: 488.57
MOL File: 73771-04-7.mol

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Prednicarbate Property

Melting point:: 110-112°; mp 183°
alpha: D20 +63° (c = 0.1 in ethanol)
Boiling point:: 640.7±55.0 °C(Predicted)
Density: 1.25±0.1 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: Practically insoluble in water, freely soluble in acetone and in ethanol (96 per cent), sparingly soluble in propylene glycol. It shows polymorphism (5.9).
pka: 14.05±0.70(Predicted)
color: White to Off-White

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Safety

HS Code: 2937290000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Precautionary statements

P201Obtain special instructions before use.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0002231
Product name: Prednicarbate for peak identification
Purity: CRS, European Pharmacopoeia (EP) Reference Standard
Packaging: Y0002231
Price: $161
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHR3101
Product name: Prednicarbate
Purity: pharmaceutical secondary standard, certified reference material
Packaging: 500MG
Price: $186
Updated: 2024/03/01

Sigma-Aldrich

Product number: P2698000
Product name: Prednicarbate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: p2698000
Price: $153
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1554909
Product name: Prednicarbate
Packaging: 200mg
Price: $358
Updated: 2024/03/01

Cayman Chemical

Product number: 23668
Product name: Prednicarbate
Purity: ≥98%
Packaging: 5mg
Price: $32
Updated: 2024/03/01

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Prednicarbate Chemical Properties,Usage,Production

Description

Prednicarbate is a potent topical antiinflammatory agent with minimal systemic effects. It is useful in the treatment of cutaneous inflammatory disorders such as eczema and psoriasis.

Description

Prednicarbate is a synthetic corticosteroid and a derivative of prednisolone . It has anti-inflammatory activity comparable to that of desoximetasone in various murine models when administered topically but lacks activity when administered subcutaneously. Topical administration of prednicarbate (2 drops of a 0.1% solution per day) induces wound healing in hairless mice. Formulations containing prednicarbate have been used to treat chronic hand eczema.

Chemical Properties

White or almost white, crystalline powder.

Originator

Hoechst AG (W. Germany)

Uses

Topical anti-inflammatory agent. Glucocorticoid.
Prednicarbate (Dermatop E) is a synthetic nonfluorinated topical corticosteroid.

Indications

Prednicarbate (Dermatop E) is a synthetic nonfluorinated topical corticosteroid.

Definition

ChEBI: Prednicarbate is a corticosteroid hormone.

brand name

Dermatop (Sanofi Aventis).

General Description

Prednicarbate, 17-[(ethoxycarbonyl)oxy]-11β-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione, is a prednisolone derivative with a C21 propionateester and a C17 ethyl carbonate group. It is availablefor use only in a 0.1% topical cream. Prednicarbate is amedium-potency GC.

Prednicarbate Preparation Products And Raw materials

Raw materials

Silica gel Acetic anhydride Propionyl chloride Prednisolone Tetraethyl orthocarbonate PARA TOLUENE Sodium bicarbonate Anhydrous pyridine

Preparation Products

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Prednicarbate Suppliers

Canada 2 China 66 Europe 2 France 1 Germany 4 India 5 Israel 2 Italy 2 United Kingdom 6 United States 18 Global 108

GUANGZHOU TOPWORK CHEMISTRY CO.,LTD.

Tel: 020-87317062 13048089691
Email: 852378519@qq.com
Country: China
ProdList: 152
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2127
Advantage: 70

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15421
Advantage: 60

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5700
Advantage: 66

Wuhan Sunrise Technology Development Co., Ltd.

Tel: 027-027-83314682 13554138826
Fax: +86 (27) 8331-4682
Email: whsrtech@vip.163.com
Country: China
ProdList: 300
Advantage: 62

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7815
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9823
Advantage: 79

Shanghai Sphchem Co., Ltd.

Tel: 21-21-56491756 13512199871
Fax: 021-5649-1756
Email: sales@panhongchem.com
Country: China
ProdList: 4001
Advantage: 55

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14059
Advantage: 65

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View Lastest Price from Prednicarbate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Prednicarbate 73771-04-7
Price: US $0.00/Kg/Bag
Min. Order: 1KG
Purity: 97%-102%; EPV
Supply Ability: 50kgs
Release date: 2021-08-11

Career Henan Chemical Co

Product: Prednicarbate 73771-04-7
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2019-07-09

73771-04-7, PrednicarbateRelated Search:

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Clindamycin 4-Phosphate Ambroxol hydrochloride N-Deformyl-N-pivaloyl Orlistat 10-Propargyl-10-deazaaminopterin Cilastatin Esmolol Impurity 2 HCl (R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethanone AMbroxol EP IMpurity D GATIFLOXACIN RELATED COMPOUND A Eflone Prednisolone-21-acetate Prednicarbate Prednicarbate Related Compound A Prednicarbate Related Compound C Prednicarbate Related Compound B Prednisolone prednisolone 17-ethylcarbonate

PREDNICARBATE

11β，17，21-Trihydroxypregna-1，4-diene-3，20-dione 17-(ethylcarbonate)-21-propionate

[2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate

Dermatop

HOE-777

Prednitop

Regemt

S-77-0777

Prednisolone 17-(ethyl carbonate) 21-propionate

Pregna-1,4-diene-3,20-dione, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)-, (11b)-

Regenit

17-[(Ethoxycarbonyl)oxy]-11β-hydroxy-21-(1-oxopropoxy)-pregna-1,4-diene-3,20-dione

17-[(Ethoxycarbonyl)oxy]-11β-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione

Prednicarbate (200 mg)

(11β)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione

Prednicarbate, >=98%

Prednicarbate for system suitability A

Prednicarbate for system suitability

Prednicarbate CRS

Prednicarbate for system suitability A CRS

Pregna-1,4-diene-3,20-dione, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)-, (11β)-

2-((8S,9S,10R,11S,13S,14S,17R)-17-((ethoxycarbonyl)oxy)-11-hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl propionate

Prednicarbate (1554909)

Dermatop E emollient

UNII-V901LV1K7D

73771-04-7

C27H36O8

Intermediates & Fine Chemicals

Pharmaceuticals

Steroids