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Prednicarbate

Product Name
Prednicarbate
CAS No.
73771-04-7
Chemical Name
Prednicarbate
Synonyms
Regemt;Regenit;HOE-777;Dermatop;Prednitop;S-77-0777;PREDNICARBATE;UNII-V901LV1K7D;Prednicarbate CRS;Prednicarbate, >=98%
CBNumber
CB5342987
Molecular Formula
C27H36O8
Formula Weight
488.57
MOL File
73771-04-7.mol
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Prednicarbate Property

Melting point:
110-112°; mp 183°
alpha 
D20 +63° (c = 0.1 in ethanol)
Boiling point:
640.7±55.0 °C(Predicted)
Density 
1.25±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Practically insoluble in water, freely soluble in acetone and in ethanol (96 per cent), sparingly soluble in propylene glycol. It shows polymorphism (5.9).
pka
14.05±0.70(Predicted)
color 
White to Off-White
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Safety

HS Code 
2937290000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Precautionary statements

P201Obtain special instructions before use.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0002231
Product name
Prednicarbate for peak identification
Purity
CRS, European Pharmacopoeia (EP) Reference Standard
Packaging
Y0002231
Price
$161
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR3101
Product name
Prednicarbate
Purity
pharmaceutical secondary standard, certified reference material
Packaging
500MG
Price
$186
Updated
2024/03/01
Sigma-Aldrich
Product number
P2698000
Product name
Prednicarbate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
p2698000
Price
$153
Updated
2024/03/01
Sigma-Aldrich
Product number
1554909
Product name
Prednicarbate
Packaging
200mg
Price
$358
Updated
2024/03/01
Cayman Chemical
Product number
23668
Product name
Prednicarbate
Purity
≥98%
Packaging
5mg
Price
$32
Updated
2024/03/01
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Prednicarbate Chemical Properties,Usage,Production

Description

Prednicarbate is a potent topical antiinflammatory agent with minimal systemic effects. It is useful in the treatment of cutaneous inflammatory disorders such as eczema and psoriasis.

Description

Prednicarbate is a synthetic corticosteroid and a derivative of prednisolone . It has anti-inflammatory activity comparable to that of desoximetasone in various murine models when administered topically but lacks activity when administered subcutaneously. Topical administration of prednicarbate (2 drops of a 0.1% solution per day) induces wound healing in hairless mice. Formulations containing prednicarbate have been used to treat chronic hand eczema.

Chemical Properties

White or almost white, crystalline powder.

Originator

Hoechst AG (W. Germany)

Uses

Topical anti-inflammatory agent. Glucocorticoid.
Prednicarbate (Dermatop E) is a synthetic nonfluorinated topical corticosteroid.

Indications

Prednicarbate (Dermatop E) is a synthetic nonfluorinated topical corticosteroid.

Definition

ChEBI: Prednicarbate is a corticosteroid hormone.

brand name

Dermatop (Sanofi Aventis).

General Description

Prednicarbate, 17-[(ethoxycarbonyl)oxy]-11β-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione, is a prednisolone derivative with a C21 propionateester and a C17 ethyl carbonate group. It is availablefor use only in a 0.1% topical cream. Prednicarbate is amedium-potency GC.

Prednicarbate Preparation Products And Raw materials

Raw materials

Preparation Products

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Prednicarbate Suppliers

Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71
Dalton Chemical Laboratories, Inc.
Tel
--
Fax
--
Email
chemist@dalton.com
Country
Canada
ProdList
965
Advantage
78
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View Lastest Price from Prednicarbate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Prednicarbate 73771-04-7
Price
US $0.00/Kg/Bag
Min. Order
1KG
Purity
97%-102%; EPV
Supply Ability
50kgs
Release date
2021-08-11
Career Henan Chemical Co
Product
Prednicarbate 73771-04-7
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2019-07-09

73771-04-7, PrednicarbateRelated Search:


  • PREDNICARBATE
  • 11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 17-(ethylcarbonate)-21-propionate
  • [2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate
  • Dermatop
  • HOE-777
  • Prednitop
  • Regemt
  • S-77-0777
  • Prednisolone 17-(ethyl carbonate) 21-propionate
  • Pregna-1,4-diene-3,20-dione, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)-, (11b)-
  • Regenit
  • 17-[(Ethoxycarbonyl)oxy]-11β-hydroxy-21-(1-oxopropoxy)-pregna-1,4-diene-3,20-dione
  • 17-[(Ethoxycarbonyl)oxy]-11β-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
  • Prednicarbate (200 mg)
  • (11β)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
  • Prednicarbate, >=98%
  • Prednicarbate for system suitability A
  • Prednicarbate for system suitability
  • Prednicarbate CRS
  • Prednicarbate for system suitability A CRS
  • Pregna-1,4-diene-3,20-dione, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)-, (11β)-
  • 2-((8S,9S,10R,11S,13S,14S,17R)-17-((ethoxycarbonyl)oxy)-11-hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl propionate
  • Prednicarbate (1554909)
  • Dermatop E emollient
  • UNII-V901LV1K7D
  • C16286450 Prednicarbate
  • 73771-04-7
  • C27H36O8
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids