Eflone

Product Name: Eflone
CAS No.: 3801-06-7
Chemical Name: Eflone
Synonyms: fluorometholone acetate;Oxylone Acetate;Flarex;eflone;U 17323;NSC 47438;Nolpitantium;Eflone USP/EP/BP;Flumetholon acetate;Lumacaftor Impurity 6
CBNumber: CB5501395
Molecular Formula: C24H31FO5
Formula Weight: 418.5
MOL File: 3801-06-7.mol

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Eflone Property

Melting point:: 230-232°
alpha: D +28° (chloroform)
Boiling point:: 532.1±50.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 13.01±0.70(Predicted)
color: Off-White to Light Yellow
InChIKey: YRFXGQHBPBMFHW-ZGNMMXMRNA-N
SMILES: [C@]12(F)[C@@]([H])(O)C[C@]3(C)[C@](CC[C@@]3([H])[C@]1([H])C[C@]([H])(C)C1=CC(=O)C=C[C@]21C)(C(=O)C)OC(=O)C |&1:0,2,6,8,11,13,16,25,r|

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Safety

HS Code: 2937220000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR3490
Product name: Fluorometholone Acetate
Purity: certified reference material, pharmaceutical secondary standard
Packaging: 400MG
Price: $260
Updated: 2025/07/31

Sigma-Aldrich

Product number: 1278109
Product name: Fluorometholone acetate
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200mg
Price: $425
Updated: 2025/07/31

TRC

Product number: F593150
Product name: Fluorometholone acetate
Packaging: 100mg
Price: $1020
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0008905
Product name: FLUOROMETHOLONE ACETATE
Purity: 95.00%
Packaging: 100MG
Price: $1593.9
Updated: 2021/12/16

AvaChem

Product number: 3058
Product name: Fluorometholone 17-acetate
Packaging: 1g
Price: $890
Updated: 2021/12/16

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Eflone Chemical Properties,Usage,Production

Chemical Properties

Off-White to Pale Yellow Solid

Uses

Fluorometholone Acetate is a glucocorticoid; anti-inflammatory.

Definition

ChEBI: A steroid ester resulting from the formal condensation of the 17-hydroxy function of fluorometholone with acetic acid. Used in the treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the eye.

brand name

Flarex (Alcon).

in vivo

Hourly topical administration of 0.1% Fluorometholone acetate ophthalmic suspension produced, on the average, a 47% reduction in the polymorphonuclear leukocytes invading the cornea during an experimentally induced inflammatory keratitis in New Zealand albino rabbits (1.5-2.0 kg). Fluorometholone acetate (0.1%) formulated as a high-viscosity carbomer gel and applied at three-hour intervals reduced invading leukocytes in the cornea an average of 48%, an effect not significantly different from hourly administration of the suspension^[1].

IC 50

CA Ⅱ

Eflone Preparation Products And Raw materials

Raw materials

Preparation Products

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Eflone Suppliers

Canada 1 China 163 Europe 2 India 5 Israel 1 Japan 1 United Kingdom 1 United States 13 Global 187

GUANGZHOU TOPWORK CHEMISTRY CO.,LTD.

Tel: 020-87317062 13048089691
Email: 852378519@qq.com
Country: China
ProdList: 198
Advantage: 58

Hunan Well Medicine Synthesis Technology Co., Ltd

Tel: 0731-85589467; 13574065797
Email: 3877753494@qq.com
Country: China
ProdList: 36
Advantage: 58

Changsha Qisheng Heyan Medical Technology Co., LTD

Tel: 18684929597
Email: 527907673@qq.com
Country: China
ProdList: 103
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 6387
Advantage: 52

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

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View Lastest Price from Eflone manufacturers

Wuhan Haorong Biotechnology Co.,Ltd

Product: Eflone / FLUROMETHOLONE ACETATE 3801-06-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5000
Release date: 2023-07-27

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: Eflone 3801-06-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20tons
Release date: 2024-03-29

Shaanxi Dideu New Materials Co. Ltd

Product: Eflone 3801-06-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-05

3801-06-7, EfloneRelated Search:

Benzyl acetate 2-Butoxyethyl acetate Fluorometholone Cellulose acetate Magnesium acetate Cupric acetate monohydrate Isopropyl acetate Butyl acetate Sodium acetate D-alpha-Tocopheryl acetate Vinyl acetate Ethylene glycol monoethyl ether acetate Ammonium acetate Ethyl acetate 1-Methoxy-2-propyl acetate ACETATE Eflone fluoro jade

9-fluoro-11β,17-dihydroxy-6α-methylpregna-1,4-diene-3,20-dione 17-acetate

FLUOROMETHOLONE ACETATE (200 MG)

9-fluoro-11b,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione 17-acetate

eflone

fluorometholone acetate

9-fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 17-acetate

Nolpitantium

FLUROMETHOLONE ACETATE

17-(Acetyloxy)-9-fluoro-11β-hydroxy-6α-methylpregna-1,4-diene-3,20-dione

(6α,11β)-17-(Acetyloxy)-9-fluoro-11-hydroxy-6-Methylpregna-1,4-diene-3,20-dione

6α-Methyl-9α-fluoro-17-acetoxy-21-deoxyprednisolone

Flarex

NSC 47438

Oxylone Acetate

U 17323

Pregna-1,4-diene-3,20-dione,17-(acetyloxy)-9-fluoro-11-hydroxy-6-Methyl-, (6a,11b)-

FluoroMetholone 17- acetate

Pregna-1,4-diene-3,20-dione, 17-(acetyloxy)-9-fluoro-11-hydroxy-6-methyl-, (6α,11β)-

Flumetholon acetate

FLUOROMETHALONE ACETATE

Eflone USP/EP/BP

Fluorometholone Acetate (1278109)

Eflone / FLUROMETHOLONE ACETATE

9-fluoro-11b,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-Chemicalbookdione17-acetate

9-fluoro-11β,17-dihydroxy-6α-methylpregna-1,4-diene-3,20-dione17-acetate

(6S,8S,9R,10S,11S,13S,14S,17R)-17-Acetyl-9-fluoro-11-hydroxy-6,10,13-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl acetate

(6s,8s,9r,10s,11s,13s,14s,17r)-17-acetyl-9-fluoro-11-hydroxy-6,10,13-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] Acetate

Lumacaftor Impurity 6

Fluorometholone Acetate, 10 mM in DMSO

3801-06-7

3801-6-7

C24H31FO5

Inhibitors

Hormone Drugs

Intermediates & Fine Chemicals

Pharmaceuticals

Steroids