D-alpha-Tocopheryl acetate

Description References

Product Name: D-alpha-Tocopheryl acetate
CAS No.: 58-95-7
Chemical Name: D-alpha-Tocopheryl acetate
Synonyms: D-α-Tocopheryl acetate;D-ALPHA-TOCOPHEROL ACETATE;Evipherol;dl-alpha-tocopheryl;α-Tocopherol acetate;D-A-TOCOPHERYL ACETATE;D-α-Tocopherol Acetate;D-alpha-Tocopheryl acetate,98%;Econ;Gevex
CBNumber: CB5241875
Molecular Formula: C31H52O3
Formula Weight: 472.74
MOL File: 58-95-7.mol

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D-alpha-Tocopheryl acetate Property

Melting point:: ~25 °C(lit.)
alpha: 3 º (c=2, in ethanol 25 ºC)
Boiling point:: 224 °C0.3 mm Hg(lit.)
Density: 0.953 g/mL at 25 °C(lit.)
refractive index: n20/D 1.496(lit.)
Flash point:: >230 °F
storage temp.: room temp
solubility: Practically insoluble in water, freely soluble in acetone, in anhydrous ethanol and in fatty oils, soluble in ethanol (96 per cent).
form: oil or semi-solid
color: yellow
Odor: cryst., odorless
Water Solubility: <0.1 g/100 mL at 17 ºC
Merck: 14,9495
Stability:: Stable. Incompatible with strong oxidizing agents.
LogP: 12.260 (est)
CAS DataBase Reference: 58-95-7(CAS DataBase Reference)
NIST Chemistry Reference: Vitamin e acetate(58-95-7)
EPA Substance Registry System: D-.alpha.-Tocopheryl acetate (58-95-7)

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Safety

Safety Statements: 24/25
WGK Germany: 1
RTECS: GP8280000
HS Code: 29362800

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T1157
Product name: (+)-α-Tocopherol acetate
Purity: BioReagent, suitable for insect cell culture, ~1360 IU/g
Packaging: 1g
Price: $21.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: T1157
Product name: (+)-α-Tocopherol acetate
Purity: BioReagent, suitable for insect cell culture, ~1360 IU/g
Packaging: 10g
Price: $65.1
Updated: 2024/03/01

TCI Chemical

Product number: T2322
Product name: D-alpha-Tocopherol Acetate
Purity: >96.0%(GC)
Packaging: 25g
Price: $154
Updated: 2024/03/01

Sigma-Aldrich

Product number: T3001
Product name: (+)-α-Tocopherol acetate
Purity: oil or semi-solid, ~1360 IU/g, semisynthetic
Packaging: 10g
Price: $97.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: T3001
Product name: (+)-α-Tocopherol acetate
Purity: oil or semi-solid, ~1360 IU/g, semisynthetic
Packaging: 25g
Price: $213
Updated: 2024/03/01

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D-alpha-Tocopheryl acetate Chemical Properties,Usage,Production

Description

D-alpha-tocopheryl acetate is a natural form of vitamin E and it is stable in terms of shelf life. It is probably the best form for people actively trying to prevent heart disease. It is used in the dietary and clinical supplementations.

References

[1] Jack Challem, User’s Guide to Nutritional Supplements, 2003
[2] M. K. Horwitt, Relative biological values of d-alpha-tocopheryl acetate and all-rac-alpha-tocopheryl acetate in man, The American Society for Clinical Nutrition, 1980, vol. 33, 1856-1860

Chemical Properties

off-white crystalline solid

Uses

Used in prevention and treatment of vitamin E deficiencies.

Uses

α-Tocopherol acetate is the most bioactive of the naturally occurring forms of Vitamin E. Richest sources are green vegetables, grains, and oils, particularly palm, safflower and sunflower oils.

Uses

(+)-α-Tocopherol acetate has been used:

as a component of growth medium for retinal cell lines
as an external standard in high performance liquid chromatography (HPLC) to study its composition in leafy vegetables
in the preparation of trans-resveratrol-encapsulated lipid nanocarriers (R-nano)

Definition

ChEBI: Alpha-Tocopherol acetate is a tocol.

General Description

Odorless off-white crystals. Darkens at 401° F.

Air & Water Reactions

D-alpha-Tocopheryl acetate may be sensitive to prolonged exposure to light and air. . Insoluble in water.

Reactivity Profile

An ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Fire Hazard

Flash point data for D-alpha-Tocopheryl acetate are not available. D-alpha-Tocopheryl acetate is probably combustible.

Biochem/physiol Actions

α-Tocopherol acetate or vitamin E-acetate has antioxidant properties and reduces lipid peroxidation. However, vitamin E acetate on pyrolysis leads to the generation of carcinogens like alkenes and benzenes.

Contact allergens

Tocopherol and tocopheryl acetate are used mainly as antioxidants. Tocopheryl acetate, an ester of tocopherol (vitamin E), can induce allergic contact dermatitis.

Safety Profile

When heated to decomposition it emits acrid smoke and irritating fumes.

D-alpha-Tocopheryl acetate Preparation Products And Raw materials

Raw materials

Trimethylhydroquinone PHYTANTRIOL Sodium acetate trihydrate

Preparation Products

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D-alpha-Tocopheryl acetate Suppliers

Belgium 1 China 240 Czech 1 Europe 3 Germany 2 India 10 Japan 2 South Korea 1 Switzerland 2 United Kingdom 5 United States 31 Global 298

J & K SCIENTIFIC LTD.

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China Langchem Inc.

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View Lastest Price from D-alpha-Tocopheryl acetate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: D-alpha-Tocopheryl acetate 58-95-7
Price: US $0.00/KG/CTN
Min. Order: 5KG
Purity: 96%-102
Supply Ability: 1000KG
Release date: 2021-06-28

Career Henan Chemical Co

Product: D-alpha-Tocopheryl acetate 58-95-7
Price: US $8.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 10MT
Release date: 2018-12-16

58-95-7, D-alpha-Tocopheryl acetateRelated Search:

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D-alpha-Tocopheryl acetate,98%

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(2R,4'R,8'R)-α-Tocopheryl Acetate

(R,R,R)-α-Tocopheryl Acetate

2,5,7,8-TetraMethyl-2-(4,8,12-triMethyltridecyl)- 6-chroManol Acetate

Copherol 12250

EVitaMin E ace

2H-1-Benzopyran-6-ol,3,4-dihydro-2,5,7,8-tetraMethyl-2-[(4R,8R)-4,8,12-triMethyltridecyl]-,6-acetate, (2R)-

Vitamin e acetate 93% Oil

(+)-ALPHA-TOCOPHEROL ACETATE

D-VITAMIN E ACETATE

D-TOCOPHEROL ACETATE

D-TOCOPHRIN

D-ECON

D-A-TOCOPHERYL ACETATE

D-CONTOPHERON

D-ALFACOL

D-ALPHA-TOCOPHEROL ACETATE

D-ALPHA-TOCOPHERYL ACETATE

D-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRIDECYL)-6-CHROMANOL ACETATE

D-FERTILVIT

[2R-[2R*(4R*

D-A-TOCOPHEROL ACETATE FROM NATURAL*A-TO COPHEROL IN

(+)-A-TOCOPHEROL ACETATE FROM NATURAL*A- TOCOPHEROL

(2R,4'R,8'R)-O-Acetyl-alpha-tocopherol-1-benzopyran-6-olacetate

[2R-[2R*(4R*,8R*)]]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol acetate

D-α-Tocopheryl acetate

2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4R,8R)-4,8,12-trimethyltridecyl-, acetate, (2R)-

VE50%ACETATE

D3-RRR-ALPHA-TOCOPHERYLACETATE

3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R*(4R*,8R*)]]-2H-1-Benzopyran-6-ol

2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl- 2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R(4R,8R)]]-

[2R-[2R*(4R8,8R*)]]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol acetate

2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-,acetate,(+)-6-chromano

2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-yl acetate

2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R*(4R*,8R*)]]-

3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-,acetate,[2R-[2R*(4R*,8R*)]]-2H-1-Benzopyran-6-ol

6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-

acetate,[2theta-[2theta(4theta,8theta)]]-yl)

aceticacid2,5,7,8-tetramethyl-2-(4,8,12-trimethyl-tridecyl)-chroman-6-ylester

Alfacol

Combinal E

combinale

Contopheron

dl-alpha-tocopheryl

Ecofrol

Econ

E-Ferol

Endo E Dompe

endoedompe

Ephynal acetate

ephynalacetate

Erevit

E-Toplex

E-vicotrat

Evipherol