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Sodium acetate trihydrate

Product Name
Sodium acetate trihydrate
CAS No.
6131-90-4
Chemical Name
Sodium acetate trihydrate
Synonyms
lnkM;NaAc;Plasmafusin;Thomaegelin;SODA CAUSTIC;Natrii acetas;3M NaAc pH5.2;SODIUM ACETATE 3H2O;SodiuM Acetate (AS);SodiumAcetate3H2OFcc
CBNumber
CB3410262
Molecular Formula
C2H9NaO5
Formula Weight
136.08
MOL File
6131-90-4.mol
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Sodium acetate trihydrate Property

Melting point:
58 °C
Boiling point:
>400°C
Density 
1,45 g/cm3
Flash point:
>250°C
storage temp. 
Store at +5°C to +30°C.
solubility 
H2O: 3 M at 20 °C, clear, colorless
form 
Solid
color 
White tranparent
Odor
Slight acetic acid
PH
7.5-9.0 (25℃, 50mg/mL in H2O)
PH Range
8.5 - 10 at 408 g/l at 25 °C
pka
4.76 (acetic acid)(at 25℃)
Water Solubility 
762 g/L (20 ºC)
λmax
λ: 260 nm Amax: ≤0.01
λ: 280 nm Amax: ≤0.01
Merck 
14,8571
BRN 
3732037
Stability:
Stable. Incompatible with strong oxidizing agents, halogens.
InChIKey
AYRVGWHSXIMRAB-UHFFFAOYSA-M
CAS DataBase Reference
6131-90-4(CAS DataBase Reference)
NIST Chemistry Reference
Sodium acetate trihydrate(6131-90-4)
EPA Substance Registry System
Acetic acid, sodium salt, trihydrate (6131-90-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
1
RTECS 
AJ4580000
Autoignition Temperature
607 °C
TSCA 
Yes
HS Code 
29152200
Toxicity
LD50 orally in Rabbit: 3530 mg/kg LD50 dermal Rabbit > 10000 mg/kg
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
7610-OP
Product name
OmniPur Sodium Acetate, Trihydrate - CAS 6131-90-4 - Calbiochem
Packaging
500 g
Price
$31.63
Updated
2021/03/22
Sigma-Aldrich
Product number
32318
Product name
Sodium acetate trihydrate
Purity
puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.5%
Packaging
500 g
Price
$41.9
Updated
2021/03/22
Sigma-Aldrich
Product number
25022
Product name
Sodium acetate trihydrate
Purity
puriss., meets analytical specification of Ph.?Eur., BP, USP, FCC, E262, 99.0-101.0% (calc. to the dried substance), ≤0.00002% Al
Packaging
1 kg
Price
$53.1
Updated
2021/03/22
Sigma-Aldrich
Product number
32318
Product name
Sodium acetate trihydrate
Purity
puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.5%
Packaging
1 kg
Price
$67.4
Updated
2021/03/22
Sigma-Aldrich
Product number
1.06267
Product name
Sodium acetate trihydrate
Purity
for analysis EMSURE? ACS,ISO,Reag. Ph Eur
Packaging
500 g
Price
$69.47
Updated
2021/03/22
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Sodium acetate trihydrate Chemical Properties,Usage,Production

Description

Sodium acetate trihydrate is the trihydrate sodium salt oaf acetic acid.
In the food industry, sodium acetate is used as an acidity regulator, emulsifier, and preservative. It can give potato chips a salt and vinegar flavor. In pharmaceutical industry, it is used for replenishing lost electrolytes, as a diuretic, and in reusable heating pads and hand warmers. Sodium acetate trihydrate can be used to neutralize the industrial mineral acids discharge. In the textile and synthetic rubber production, it is used to neutralize sulfuric acids, facilitate aniline dye take up, and protect aniline day. In the leather industry, it is used as a buffering agent for leather tanning. Furthermore, sodium acetate trihydrate is used as buffers in the production of cosmetics and petroleum products and in electroplating industry.

Chemical Properties

white to colourless crystals or powder

Chemical Properties

Anhydrous salt is a colorless crystalline solid; density 1.528 g/cm3; melts at 324°C; very soluble in water; moderately soluble in ethanol. The colorless crystalline trihydrate has a density 1.45 g/cm3; decomposes at 58°C; is very soluble in water; pH of 0.1M aqueous solution is 8.9; moderately soluble in ethanol, 5.3 g/100mL.

Chemical Properties

Sodium acetate occurs as colorless, transparent crystals or a granular crystalline powder with a slight acetic acid odor.

Uses

Used as buffers.

Uses

Sodium acetate is a mordant in dyeing. Other applications are in photography, as an additive to food, in purification of glucose, in preservation of meat, in tanning, and as a dehydrating agent. In analytical chemistry it is used to prepare buffer solution.

Preparation

Sodium acetate is prepared by reacting sodium hydroxide or sodium carbonate with acetic acid in aqueous solution. The solution is evaporated to obtain hydrated crystals of sodium acetate.
NaOH + CH3COOH → CH3COONa + H2O
Na2CO3 + CH3COOH → 2CH3COONa + CO2 + H2O

Production Methods

Sodium acetate is prepared by neutralization of acetic acid with sodium carbonate.

Pharmaceutical Applications

Sodium acetate is used as part of a buffer system when combined with acetic acid in various intramuscular, intravenous, topical, ophthalmic, nasal, oral, otic, and subcutaneous formulations. It may be used to reduce the bitterness of oral pharmaceuticals. It can be used to enhance the antimicrobial properties of formulations; it has been shown to inhibit the growth of S. aureus and E. coli, but not C. albicans in protein hydrolysate solutions. It is widely used in the food industry as a preservative. Sodium acetate has also been used therapeutically for the treatment of metabolic acidosis in premature infants, and in hemodialysis solutions.

Safety

Sodium acetate is widely used in cosmetics, foods, and pharmaceutical formulations, and is generally regarded as a nontoxic and nonirritant material.
A short-term feeding study in chickens with a diet supplemented with 5.44% sodium acetate showed reduced growth rates that were attributed to the sodium content.(9) Sodium acetate is poisonous if injected intravenously, is moderately toxic by ingestion, and is an irritant to the skin and eyes.
LD50 (rat, oral): 3.53 g/kg
LD50 (mouse, IV): 0.38 g/kg
LD50 (mouse, SC): 8.0 g/kg

storage

Sodium acetate should be stored in airtight containers.

Incompatibilities

Sodium acetate reacts with acidic and basic components. It will react violently with fluorine, potassium nitrate, and diketene.

Regulatory Status

GRAS listed. Accepted as a food additive in Europe. Included in the FDA Inactive Ingredients Database (injections, nasal, otic, ophthalmic, and oral preparations).

References

[1] http://www.europlat.org
[2] http://www.rxlist.com/sodium-acetate-drug.htm
[3] http://cosmetics.specialchem.com
[4] http://cecri.csircentral.net/2710/1/036-96.pdf

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Sodium acetate trihydrate Suppliers

Langfang Tianke Biological Technology Co., Ltd.
Tel
0316-5569331-
Email
15076659665@126.com
Country
China
ProdList
1
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
021-20337333-801
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
24980
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65
VWR(Shanghai) Co., Ltd
Tel
400-821-8006
Fax
+86-21-58558801
Email
info_china@vwr.com
Country
China
ProdList
3044
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Jiangsu Kolod Food Ingredients Co.,Ltd.
Tel
0518-85110930-
Fax
0518-85115307
Email
sales2158@jskolod.com
Country
China
ProdList
86
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58
Aikon International Limited
Tel
025-58859352-
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
12931
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58
Hubei Qifei Pharmaceutical Chemical Co., Ltd
Tel
027-59322506- ;027-59322506-
Fax
027-59322506
Email
1438082200@qq.com;1438480055@qq.com
Country
China
ProdList
9587
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Langfang Lanjieer Fine Chemical Co. LTD
Tel
0316-5903511-
Fax
13215443532
Email
2152944868@qq.com
Country
China
ProdList
292
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58
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
21-61259100-
Fax
86-21-61259102
Email
sh@meryer.com
Country
China
ProdList
40264
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15877
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69
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View Lastest Price from Sodium acetate trihydrate manufacturers

Hebei Dongdu Import and Export Co. LTD
Product
Sodium Acetate Trihydrate 6131-90-4
Price
US $1000.00/T
Min. Order
1KG
Purity
99.9%
Supply Ability
20tons
Release date
2021-03-03
Hebei Dongdu Import and Export Co. LTD
Product
Sodium Acetate Trihydrate 1 6131-90-4
Price
US $690.00/T
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2021-03-01
HEBEI YINGONG NEW MATERIAL TECHNOLOGY CO.,LTD
Product
sodium acetate trihydrate 6131-90-4
Price
US $150.00/ASSAYS
Min. Order
10g
Purity
>99%
Supply Ability
500kg/month
Release date
2021-09-15

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