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Sodium acetate trihydrate

Product Name
Sodium acetate trihydrate
CAS No.
6131-90-4
Chemical Name
Sodium acetate trihydrate
Synonyms
NaAc;SODA CAUSTIC;Sodium acetate crystal;SODIUM ACETATE 3H2O;SODIUM ACETATE, TRIHYDRATE, REAGENT (ACS)SODIUM ACETATE, TRIHYDRATE, REAGENT (ACS)SODIUM ACETATE, TRIHYDRATE, REAGENT (ACS);lnkM;abs9264;Plasmafusin;Thomaegelin;Natrii acetas
CBNumber
CB3410262
Molecular Formula
C2H9NaO5
Formula Weight
136.08
MOL File
6131-90-4.mol
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Sodium acetate trihydrate Property

Melting point:
58 °C
Boiling point:
>400°C
Density 
1,45 g/cm3
Flash point:
>250°C
storage temp. 
Store at +5°C to +30°C.
solubility 
H2O: 3 M at 20 °C, clear, colorless
form 
Solid
color 
White
PH
7.5-9.0 (25℃, 50mg/mL in H2O)
pka
4.76 (acetic acid)(at 25℃)
Odor
Slight acetic acid
PH Range
8.5 - 10 at 408 g/l at 25 °C
Water Solubility 
762 g/L (20 ºC)
λmax
λ: 260 nm Amax: ≤0.01
λ: 280 nm Amax: ≤0.01
Merck 
14,8571
BRN 
3732037
Stability:
Stable. Incompatible with strong oxidizing agents, halogens.
InChIKey
AYRVGWHSXIMRAB-UHFFFAOYSA-M
LogP
-0.285 (est)
CAS DataBase Reference
6131-90-4(CAS DataBase Reference)
NIST Chemistry Reference
Sodium acetate trihydrate(6131-90-4)
EPA Substance Registry System
Acetic acid, sodium salt, trihydrate (6131-90-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
1
RTECS 
AJ4580000
Autoignition Temperature
607 °C
TSCA 
Yes
HS Code 
29152200
Toxicity
LD50 orally in Rabbit: 3530 mg/kg LD50 dermal Rabbit > 10000 mg/kg
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SX0255
Product name
Sodium acetate trihydrate
Purity
Meets ACS Specifications GR ACS
Packaging
12kg
Price
$407
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR2618
Product name
Sodium Acetate Trihydrate
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
2G
Price
$267
Updated
2024/03/01
Sigma-Aldrich
Product number
7610-OP
Product name
OmniPur Sodium Acetate, Trihydrate - CAS 6131-90-4 - Calbiochem
Packaging
500g
Price
$45
Updated
2024/03/01
Sigma-Aldrich
Product number
5.43833
Product name
Sodium acetate trihydrate
Purity
for HPLC LiChropur?
Packaging
100G
Price
$138
Updated
2024/03/01
Sigma-Aldrich
Product number
32318
Product name
Sodium acetate trihydrate
Purity
puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.5%
Packaging
500g
Price
$49.6
Updated
2024/03/01
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Sodium acetate trihydrate Chemical Properties,Usage,Production

Chemical Properties

Sodium acetate trihydrate is the trihydrate sodium salt oaf acetic acid. It is a colorless, odorless crystals that can be weathered in the air. Soluble in water and ether, pH of 0.1M aqueous solution is 8.9. moderately soluble in ethanol, 5.3 g/100mL. Anhydrous Sodium acetate occurs as colorless, transparent crystals or a granular crystalline powder with a slight acetic acid odor.

Uses

Sodium acetate trihydrate is used in various applications. It is used as a buffer of a pH range in between to 4.0 to 6.0. It is also used in the purification and precipitation of nucleic acids and in protein crystallization. It is used as a mordant dyeing, as a pickling agent in chrome tanning, as a neutralizer in waste streams containing sulfuric acid, in the textile industry and as a photoresist while using aniline dyes. It plays an important role to retard vulcanization of chloroprene in synthetic rubber production. It is a precursor to prepare ester from alkyl halide. Other applications are in photography, as an additive to food, in purification of glucose, in preservation of meat, in tanning, and as a dehydrating agent. In analytical chemistry it is used to prepare buffer solution.

Definition

ChEBI: Sodium acetate trihydrate is a hydrate. It contains a sodium acetate.

Preparation

Sodium acetate is prepared by reacting sodium hydroxide or sodium carbonate with acetic acid in aqueous solution. The solution is evaporated to obtain hydrated crystals of sodium acetate.
NaOH + CH3COOH → CH3COONa + H2O
Na2CO3 + CH3COOH → 2CH3COONa + CO2 + H2O

General Description

Sodium acetate trihydrate can be obtained from the crystallization of sodium acetate in water. On heating at 75°C, it melts, while on heating above 120°C it loses water of crystallization and gets converted into anhydrous form. The hyperfine proton and 13C splittings have been evaluated by recording ESR spectra of its irradiated single crystals. ESR studies suggested the existence of trapped methyl radicals. Its crystals are monoclinic and its crystal structure has been investigated by photographic methods. Unit cell parameters were evaluated.

Pharmaceutical Applications

Sodium acetate is used as part of a buffer system when combined with acetic acid in various intramuscular, intravenous, topical, ophthalmic, nasal, oral, otic, and subcutaneous formulations. It may be used to reduce the bitterness of oral pharmaceuticals. It can be used to enhance the antimicrobial properties of formulations; it has been shown to inhibit the growth of S. aureus and E. coli, but not C. albicans in protein hydrolysate solutions. It is widely used in the food industry as a preservative. Sodium acetate has also been used therapeutically for the treatment of metabolic acidosis in premature infants, and in hemodialysis solutions.

Biochem/physiol Actions

Sodium acetate trihydrate (SAT) is a phase change material (PCM) that can be easily combined with the preparation of domestic hot water, space heating, solar heating, and radiant floor heating systems. The hydrated salt of SAT possesses high latent heat density and thus can be used for low-temperature heat storage.

Safety

Sodium acetate is widely used in cosmetics, foods, and pharmaceutical formulations, and is generally regarded as a nontoxic and nonirritant material.
A short-term feeding study in chickens with a diet supplemented with 5.44% sodium acetate showed reduced growth rates that were attributed to the sodium content.(9) Sodium acetate is poisonous if injected intravenously, is moderately toxic by ingestion, and is an irritant to the skin and eyes.
LD50 (rat, oral): 3.53 g/kg
LD50 (mouse, IV): 0.38 g/kg
LD50 (mouse, SC): 8.0 g/kg

storage

Sodium acetate should be stored in airtight containers.

Incompatibilities

Sodium acetate reacts with acidic and basic components. It will react violently with fluorine, potassium nitrate, and diketene.

Regulatory Status

GRAS listed. Accepted as a food additive in Europe. Included in the FDA Inactive Ingredients Database (injections, nasal, otic, ophthalmic, and oral preparations).

References

[1] http://www.europlat.org
[2] http://www.rxlist.com/sodium-acetate-drug.htm
[3] http://cosmetics.specialchem.com
[4] http://cecri.csircentral.net/2710/1/036-96.pdf

Sodium acetate trihydrate Preparation Products And Raw materials

Raw materials

Acetic acid solution Acetic acid Sodium hydroxide Activated carbon Sodium carbonate

Preparation Products

Gardenia blue pigment Pigment Yellow 83 5-Ethyl-2-thiophenecarboxaldehyde BISPYRAZOLONE LEAD PHOSPHITE, DIBASIC 6-HYDROXY-7-METHOXYCOUMARIN Pigment Red 32 Pigment Red 13 Pigment Yellow 65 o-Anisic acid VINYL STEARATE 3-(2-FURYL)ISOXAZOL-5-AMINE Pigment Red 175 RHODINYL ACETATE softener IS Phenethyl acetate Sodium diacetate 8-METHOXYCOUMARIN D-alpha-Tocopheryl acetate Geranyl acetate 3-Amino-5-phenylpyrazole 2,6-Dithiopurine ACID BLUE 92 glyceryl ethercarboxylic acid salt 3,3'-Dihydroxybenzidine 6-METHOXYCOUMARIN Cefotaxime PALMITIC ACID VINYL ESTER 2-Acetyl pyrrole 1,2,3,4-TETRAHYDRO-9-ACRIDINAMINE 2-AMINO-4-(4-CHLORO-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER 5-METHYL-4-ISOXAZOLECARBONYL CHLORIDE 4-Hydroxy-3-methoxystyrene C. I. Pigment Red 258 7-isopropyl-4-methyloxepan-2-one 5-[(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)METHYL]-2-FURALDEHYDE 6-AMINO-5-NITROSO-3-METHYLURACIL Cephalothin sodium Coumarin 30 ISOXANTHOPTERIN
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Sodium acetate trihydrate Suppliers

Belgium 2 Brazil 1 Canada 5 China 508 Czech 1 Czech Republic 2 Europe 3 France 2 Germany 9 India 84 Japan 5 Mexico 1 Singapore 1 Spain 1 Switzerland 1 The Netherlands 1 United Kingdom 9 United States 68 USA 1 Global 705
Langfang Naco New Material Technology Co., Ltd.
Tel
0316-3287265 15003160716
Email
904945822@qq.com
Country
China
ProdList
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
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Lianyungang Kexin Chemical Co., Ltd.
Tel
518-518-+86-188051 +86-18805133257
Fax
051885110578
Email
sales3257@jskolod.com
Country
China
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NANJING YIHUA BIOTECHNOLOGY Co., Ltd
Tel
15171470753
Email
3105244229@qq.com
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China
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J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
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jkinfo@jkchemical.com
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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021-61259108 18621169109
Fax
86-21-61259102
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market03@meryer.com
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China
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3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
Fax
86-21-50328109
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3bsc@sina.com
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China
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Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
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China
ProdList
30123
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Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820 13031183356
Fax
010-60270825
Email
elainezt@sina.com
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China
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Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
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View Lastest Price from Sodium acetate trihydrate manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Sodium Acetatesodium Acetate 6131-90-4
Price
US $180.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-06-06
Shanghai UCHEM Inc.
Product
Sodium acetate trihydrate 6131-90-4
Price
US $73.00/kg
Min. Order
1kg
Purity
60%/99%
Supply Ability
100kg
Release date
2023-10-30
Hebei Weibang Biotechnology Co., Ltd
Product
Sodium acetate trihydrate 6131-90-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-01

6131-90-4, Sodium acetate trihydrateRelated Search:

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