Retinyl acetate

Description Reference

Product Name: Retinyl acetate
CAS No.: 127-47-9
Chemical Name: Retinyl acetate
Synonyms: VITAMIN A ACETATE;RETINOL ACETATE;retinyl;VITAMIN A ACETAT;RETINOL ACETATE ALL TRANS;ALL-TRANS-RETINYL ACETATE;Myvak;Myvax;Crystalets;VitaMin A ace
CBNumber: CB4308339
Molecular Formula: C22H32O2
Formula Weight: 328.49
MOL File: 127-47-9.mol

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Retinyl acetate Property

Melting point:: 57-58 °C
Boiling point:: 406.22°C (rough estimate)
Density: 1.0474 (rough estimate)
refractive index: 1.547-1.555
Flash point:: 14℃
storage temp.: 2-8°C
solubility: absolute ethanol: 25 mg/mL
form: solid or viscous liquid
color: Yellow powder
Odor: Amine like
Water Solubility: soluble
Sensitive: Light & Air Sensitive & Hygroscopic
Merck: 14,10013
BRN: 1915439
Stability:: Hygroscopic, Light Sensitive
InChIKey: QGNJRVVDBSJHIZ-QHLGVNSISA-N
LogP: 9.4 at 25℃
CAS DataBase Reference: 127-47-9(CAS DataBase Reference)
NIST Chemistry Reference: Retinol, acetate(127-47-9)
EPA Substance Registry System: Retinol acetate (127-47-9)

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Safety

Hazard Codes: Xn,Xi,T,F
Risk Statements: 38-63-36/37/38-53-61-11
Safety Statements: 36/37-45-37/39-26-53-16
RIDADR: UN1170 - class 3 - PG 2 - Ethanol
WGK Germany: 2
RTECS: VH6825000
F: 1-8-10
TSCA: Yes
HS Code: 29362100
Toxicity: LD50 (10 day) orally in mice: 4100 mg/kg (Kamm)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H360May damage fertility or the unborn child

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P201Obtain special instructions before use.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: V-040
Product name: Retinyl acetate solution
Purity: 100?μg/mL in ethanol (with 0.1% (w/v) BHT; degassed), reference material, Cerilliant?
Packaging: 1mL
Price: $106
Updated: 2024/03/01

Sigma-Aldrich

Product number: 46958
Product name: Retinyl acetate
Purity: analytical standard
Packaging: 100mg
Price: $143
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1716002
Product name: Retinyl acetate
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 10x0.5g
Price: $410
Updated: 2022/05/15

Alfa Aesar

Product number: A16237
Product name: Vitamin A acetate in gelatin, 500,000 I.U./g
Packaging: 25g
Price: $35.2
Updated: 2021/12/16

Alfa Aesar

Product number: A16237
Product name: Vitamin A acetate in gelatin, 500,000 I.U./g
Packaging: 100g
Price: $90
Updated: 2021/12/16

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Retinyl acetate Chemical Properties,Usage,Production

Description

Retinyl acetate (retinol acetate, vitamin A acetate,127-47-9) is a natural form of vitamin A. It is the acetate ester of retinol. It consists of yellow crystals which are greasy or sticky. It has a mild, characteristic odor. It has potential antineoplastic and chemo-preventive activities. It can be used to fortify food with vitamin A. As vitamin A acetate can induce cell differentiation and inhibit cell proliferation, it is used in skin-conditioning agent.

Reference

Volker Bühler, Vademecum for Vitamin Formulations, 2001, ISBN 3-8047-1834-5

Chemical Properties

Crystalline

Uses

vitamin precursor

Uses

Essential micronutrient

Uses

Retinyl acetate has been used:

a control diet to study its effect at different developmental periods in fish larvae
to study its inhibitory effects on Mycobacterium avium?subspecies?paratuberculosis?(MAP) strains
as an internal standard in high performance liquid chromatography (HPLC) to quantify vitamin A in fortified milk

Definition

ChEBI: Retinyl acetate is an acetate ester. It is functionally related to an all-trans-retinol.

General Description

Retinyl acetate is suitable for use in the retention identification of the analyte when using HPLC and GC. Not intended for use as an activity reference standard. It has been thoroughly evaluated to ensure the utmost quality. Neat, unless otherwise noted. Certificate of Composition provided with the purchase.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as required. Retinyl acetate is used in a wide range of biological applications. It acts as a chemopreventive agent. Retinyl acetate also has antineoplastic property.

Safety Profile

Moderately toxic by ingestion. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. See also VITAMIN A.

Purification Methods

The acetate is separated from retinol by column chromatography, then crystallised from MeOH. [Kofler and Rubin Vitamins and Hormones (NY) 18 315 1960 for purification methods]. Store it in the dark, under N2 or Ar, at 0o. [Beilstein 6 IV 4135.]

Retinyl acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Retinyl acetate Suppliers

Australia 1 Belgium 1 Brazil 1 Canada 4 China 441 Czech Republic 2 Denmark 1 Egypt 1 Europe 3 France 2 Germany 13 India 49 Indonesia 1 Ireland 1 Italy 1 Japan 5 Poland 2 Slovakia 1 South Korea 1 Spain 3 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 9 United States 58 Global 605

future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: sales@jonln.com
Country: China
ProdList: 1995
Advantage: 65

Hebei Zhentian Food Additives Co., Ltd.

Tel: 0319-5925599 13373390591
Fax: 0319 5925599
Email: 13933732699@163.com
Country: China
ProdList: 12185
Advantage: 58

Spec-Chem Industry Inc.

Tel: 025-84523390 13505162978
Email: sc@specchemind.com
Country: China
ProdList: 117
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Hubei wei shi reagent group ltd., company

Tel: 027-59102966 18717199209
Email: 2853877583@QQ.com
Country: China
ProdList: 7850
Advantage: 58

Hebei Zhentian food additives Co., LTD

Tel: 0319-5925599 13373390591
Email: 13933732699@163.com
Country: China
ProdList: 12271
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44689
Advantage: 61

Wuhan Wei Shunda Technology Development Co., Ltd.

Tel: 86-027-88774375
Fax: 86-027-88416321
Email: mwmwhot@163.com
Country: China
ProdList: 233
Advantage: 65

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View Lastest Price from Retinyl acetate manufacturers

HebeiShuoshengImportandExportco.,Ltd

Product: ALL-TRANS-RETINYL ACETATE 127-47-9
Price: US $6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000KG/Month
Release date: 2024-08-07

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Retinyl acetate 127-47-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 500kg/month
Release date: 2021-07-19

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Retinyl acetate 127-47-9
Price: US $99.00-35.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000 ton
Release date: 2024-05-09

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Retinyl acetate solution

Retinyl Acetate (Vitamin A Acetate)

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VITAMINAACETATE,USP

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VITAMIN A ACETATE(RETINOL ACETATE)(AS)

Antixerophthalmic vitamin acetate

(2E,4E,6E,8E)

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nona-2,4,6,8-tetraen-1-yl acetate

Retinol acetate Vitamin A acetate all-trans Vitamin A acetate all-trans-Retinyl acetate

Retinal acetate

Vitamin A Acetate, all trans(Synthetic) 500,000 USP u/g

Vitamin A Acetate 1000 IU Feed Grade

Retinyl acetate, 2750 IU/mg

Water Soluble Retinyl Acetate (Vitamin A Acetate), Liposomal Retinyl Acetate, Retinyl Acetate NanoEmusion

ALL-TRANS-RETINYL ACETATE

ALL-TRANS VITAMIN A ACETATE

3,7-Dimethyl-9-(2,6,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol acetate

All-trans-retinol acetate

Crystalets

Davitan A 650

Myvak

Myvax