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D-alpha-Tocopheryl acetate

Description References
Product Name
D-alpha-Tocopheryl acetate
CAS No.
58-95-7
Chemical Name
D-alpha-Tocopheryl acetate
Synonyms
D-α-Tocopheryl acetate;D-ALPHA-TOCOPHEROL ACETATE;Evipherol;dl-alpha-tocopheryl;α-Tocopherol acetate;D-A-TOCOPHERYL ACETATE;D-α-Tocopherol Acetate;D-alpha-Tocopheryl acetate,98%;Econ;Gevex
CBNumber
CB5241875
Molecular Formula
C31H52O3
Formula Weight
472.74
MOL File
58-95-7.mol
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D-alpha-Tocopheryl acetate Property

Melting point:
~25 °C(lit.)
alpha 
3 º (c=2, in ethanol 25 ºC)
Boiling point:
224 °C0.3 mm Hg(lit.)
Density 
0.953 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.496(lit.)
Flash point:
>230 °F
storage temp. 
room temp
solubility 
Practically insoluble in water, freely soluble in acetone, in anhydrous ethanol and in fatty oils, soluble in ethanol (96 per cent).
form 
oil or semi-solid
color 
yellow
Odor
cryst., odorless
Water Solubility 
<0.1 g/100 mL at 17 ºC
Merck 
14,9495
Stability:
Stable. Incompatible with strong oxidizing agents.
LogP
12.260 (est)
CAS DataBase Reference
58-95-7(CAS DataBase Reference)
NIST Chemistry Reference
Vitamin e acetate(58-95-7)
EPA Substance Registry System
D-.alpha.-Tocopheryl acetate (58-95-7)
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Safety

Safety Statements 
24/25
WGK Germany 
1
RTECS 
GP8280000
HS Code 
29362800
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T1157
Product name
(+)-α-Tocopherol acetate
Purity
BioReagent, suitable for insect cell culture, ~1360 IU/g
Packaging
1g
Price
$21.9
Updated
2024/03/01
Sigma-Aldrich
Product number
T1157
Product name
(+)-α-Tocopherol acetate
Purity
BioReagent, suitable for insect cell culture, ~1360 IU/g
Packaging
10g
Price
$65.1
Updated
2024/03/01
TCI Chemical
Product number
T2322
Product name
D-alpha-Tocopherol Acetate
Purity
>96.0%(GC)
Packaging
25g
Price
$154
Updated
2024/03/01
Sigma-Aldrich
Product number
T3001
Product name
(+)-α-Tocopherol acetate
Purity
oil or semi-solid, ~1360 IU/g, semisynthetic
Packaging
10g
Price
$97.7
Updated
2024/03/01
Sigma-Aldrich
Product number
T3001
Product name
(+)-α-Tocopherol acetate
Purity
oil or semi-solid, ~1360 IU/g, semisynthetic
Packaging
25g
Price
$213
Updated
2024/03/01
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D-alpha-Tocopheryl acetate Chemical Properties,Usage,Production

Description

D-alpha-tocopheryl acetate is a natural form of vitamin E and it is stable in terms of shelf life. It is probably the best form for people actively trying to prevent heart disease. It is used in the dietary and clinical supplementations.

References

[1] Jack Challem, User’s Guide to Nutritional Supplements, 2003
[2] M. K. Horwitt, Relative biological values of d-alpha-tocopheryl acetate and all-rac-alpha-tocopheryl acetate in man, The American Society for Clinical Nutrition, 1980, vol. 33, 1856-1860

Chemical Properties

off-white crystalline solid

Uses

Used in prevention and treatment of vitamin E deficiencies.

Uses

α-Tocopherol acetate is the most bioactive of the naturally occurring forms of Vitamin E. Richest sources are green vegetables, grains, and oils, particularly palm, safflower and sunflower oils.

Uses

(+)-α-Tocopherol acetate has been used:

  • as a component of growth medium for retinal cell lines
  • as an external standard in high performance liquid chromatography (HPLC) to study its composition in leafy vegetables
  • in the preparation of trans-resveratrol-encapsulated lipid nanocarriers (R-nano)

Definition

ChEBI: Alpha-Tocopherol acetate is a tocol.

General Description

Odorless off-white crystals. Darkens at 401° F.

Air & Water Reactions

D-alpha-Tocopheryl acetate may be sensitive to prolonged exposure to light and air. . Insoluble in water.

Reactivity Profile

An ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Fire Hazard

Flash point data for D-alpha-Tocopheryl acetate are not available. D-alpha-Tocopheryl acetate is probably combustible.

Biochem/physiol Actions

α-Tocopherol acetate or vitamin E-acetate has antioxidant properties and reduces lipid peroxidation. However, vitamin E acetate on pyrolysis leads to the generation of carcinogens like alkenes and benzenes.

Contact allergens

Tocopherol and tocopheryl acetate are used mainly as antioxidants. Tocopheryl acetate, an ester of tocopherol (vitamin E), can induce allergic contact dermatitis.

Safety Profile

When heated to decomposition it emits acrid smoke and irritating fumes.

D-alpha-Tocopheryl acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from D-alpha-Tocopheryl acetate manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
D-alpha-Tocopheryl acetate 58-95-7
Price
US $55.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2024-11-19
Chongqing Zhihe Biopharmaceutical Co., Ltd.
Product
D-alpha-Tocopheryl acetate 58-95-7
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
99%
Supply Ability
20tons
Release date
2024-05-21
WUHAN FORTUNA CHEMICAL CO., LTD
Product
D-alpha-Tocopheryl acetate 58-95-7
Price
US $0.00/KG/CTN
Min. Order
5KG
Purity
96%-102
Supply Ability
1000KG
Release date
2021-06-28

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