Btk inhibitor 1 (R enantioMer hydrochloride)

Product Name: Btk inhibitor 1 (R enantioMer hydrochloride)
CAS No.: 1553977-42-6
Chemical Name: Btk inhibitor 1 (R enantioMer hydrochloride)
Synonyms: IBT6A hydrochloride;Btk inhibitor 1 R enantiomer HCl;Btk inhibitor 1 (R enantioMer hydrochloride);BTK INHIBITOR 1 R ENANTIOMER HYDROCHLORIDE (IBRUTINIB ANALOG HYDROCHLORIDE);(R)-3-(4-phenoxyphenyl)-1-(piperidine-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride;3-(4-Phenoxyphenyl)-1-(3R)-3-piperidinyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride (1:1);Ibrutinib N-Desacryloyl Impurity HCl/(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride
CBNumber: CB32685923
Molecular Formula: C22H23ClN6O
Formula Weight: 422.91062
MOL File: 1553977-42-6.mol

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Btk inhibitor 1 (R enantioMer hydrochloride) Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-2436
Product name: IBT6Ahydrochloride
Purity: 99.22%
Packaging: 5mg
Price: $420
Updated: 2021/12/16

ChemScene

Product number: CS-2436
Product name: IBT6Ahydrochloride
Purity: 99.22%
Packaging: 10mg
Price: $600
Updated: 2021/12/16

ChemScene

Product number: CS-2436
Product name: IBT6Ahydrochloride
Purity: 99.22%
Packaging: 50mg
Price: $1800
Updated: 2021/12/16

ChemScene

Product number: CS-2436
Product name: IBT6Ahydrochloride
Purity: 99.22%
Packaging: 100mg
Price: $2520
Updated: 2021/12/16

Chemenu

Product number: CM151833
Product name: (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-aminehydrochloride
Purity: 98%
Packaging: 100mg
Price: $1278
Updated: 2021/12/16

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Btk inhibitor 1 (R enantioMer hydrochloride) Chemical Properties,Usage,Production

Description

Btk inhibitor 1R enantiomer Hcl is a pyrazolo[3,4-d]pyrimidine derivative as a Btk kinase inhibitor.IC50 value:Target: BtkFrom PCT Int. Appl. (2012), WO 2012158843 A2 20121122.

Uses

IBT6A hydrochloride is an impurity of Ibrutinib. IBT6A can be used in synthesis of IBT6A Ibrutinib dimer and IBT6A adduct[1]. Ibrutinib is a selective, irreversible Btk inhibitor with an IC50 of 0.5 nM[2].

References

[1]. PCT Int. Appl. (2012), WO 2012158843 A2 20121122.

Btk inhibitor 1 (R enantioMer hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

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Btk inhibitor 1 (R enantioMer hydrochloride) Suppliers

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1553977-42-6, Btk inhibitor 1 (R enantioMer hydrochloride)Related Search:

(R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate Ibrutinib D5 2-Propen-1-one, 1-[4-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-1-piperidinyl]- 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine Ibrutinib Impurity 21 Ibrutinib Impurity 6 (S)-1-Boc-3-hydroxypiperidine (R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-3-chloropropan-1-one Ibrutinib Impurity 6 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine 2-Propen-1-one, 1-[(3R)-3-[4-amino-7-oxido-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]- (R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethanone Ibrutinib Dimer Impurity Ibrutinib

BTK INHIBITOR 1 R ENANTIOMER HYDROCHLORIDE (IBRUTINIB ANALOG HYDROCHLORIDE)

Btk inhibitor 1 (R enantioMer hydrochloride)

3-(4-Phenoxyphenyl)-1-(3R)-3-piperidinyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride (1:1)

Btk inhibitor 1 R enantiomer HCl

IBT6A hydrochloride

(R)-3-(4-phenoxyphenyl)-1-(piperidine-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride

Ibrutinib N-Desacryloyl Impurity HCl/(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride

1553977-42-6

C22H22N6OHCl