(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one

Product Name: (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
CAS No.: 123367-26-0
Chemical Name: (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
Synonyms: Imatinib impurity J;Irutinib Impurity A;(E)-3-(dimethylamino);Imatinib EP impuritiesA;Imatinib Mesilate Impurity A;Imatinib Mesilate EP Impurity A;Nilotinib Impurity 16 (Imatinib EP Impurity A);Imatinib EP Impurity A (Nilotinib Impurity 16);(E)-3-(Dimethylamino)-1-(3-pyridyl)-2-propen-1-one;(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
CBNumber: CB72516261
Molecular Formula: C10H12N2O
Formula Weight: 176.22
MOL File: 123367-26-0.mol

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(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Property

Melting point:: 113℃
Boiling point:: 281℃
Density: 1.070
Flash point:: 124℃
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 4.74±0.70(Predicted)
color: Dark Brown to Very Dark Brown

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: D462115
Product name: (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
Packaging: 250mg
Price: $50
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-1-DW
Product name: (2E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
Purity: 98.0%
Packaging: 250mg
Price: $65
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-1-DW
Product name: (2E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
Purity: 98.0%
Packaging: 1g
Price: $95
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-1-DW
Product name: (2E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
Purity: 98.0%
Packaging: 5G
Price: $295
Updated: 2021/12/16

Alichem

Product number: 123367260
Product name: (E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
Packaging: 500g
Price: $296.8
Updated: 2021/12/16

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(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Chemical Properties,Usage,Production

Description

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one is a pharmaceutical intermediate used as an intermediate of nilotinib, a targeted anticancer drug for the treatment of chronic myeloid leukaemia (CML).

Uses

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one acts as a reagent for the synthesis of oxindole-linked indolyl-pyrimidine derivatives which are potential cytotoxic agents.

Solubility in organics

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one is soluble in chloroform and dichloromethane.

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

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(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Suppliers

Belgium 1 China 83 Finland 2 Germany 1 India 3 United Kingdom 1 United States 12 Global 103

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
Advantage: 59

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
Advantage: 65

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 5047
Advantage: 50

NovoChemy Ltd.

Tel: 021-31261262/ 49 (0)17662837245
Fax: (0)21-33250524
Email: sales@novochemy.com
Country: Germany
ProdList: 6328
Advantage: 58

NCE Biomedical Co.,Ltd.

Tel: 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax: +86-27-87599188
Country: China
ProdList: 1493
Advantage: 55

Moltt Biocem Co., Ltd.

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Fax: +86-21-38682181
Country: China
ProdList: 282
Advantage: 55

Alputon Inc.

Tel: 021-60753308-14013
Fax: 021-60753309
Country: China
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Taizhou Tongxin Bio-Tech Co., Ltd

Tel: 0523-18601685-898 18652728585
Email: sales@allyrise.com
Country: China
ProdList: 2782
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Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41462
Advantage: 60

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-66023220 0086-15250997978
Fax: 025-58362220
Email: 1511893459@qq.com
Country: China
ProdList: 7850
Advantage: 55

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View Lastest Price from (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one manufacturers

Career Henan Chemical Co

Product: (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one 123367-26-0
Price: US $1.00/g
Min. Order: 1g
Purity: ≥98%
Supply Ability: g/kg/Ton
Release date: 2019-12-25

123367-26-0, (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-oneRelated Search:

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine 2-Propen-1-one, 1-[(3R)-3-[4-amino-7-oxido-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]- Imatinib Impurity 38 Ibrutinib Impurity 28 (R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethanone Imatinib Impurity 4 Ibrutinib Impurity 5 Ibrutinib Dimer Impurity Imatinib Impurity 7 (S)-Ibrutinib (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one 1-Piperidinecarboxylic acid, 3-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-, 1,1-diMethylethyl ester, (3R)- N-(2-Methyl-4-nitrophenyl)-4-(3-pyridinyl)-2-pyrimidinamine N-DESMETHYL IMATINIB 4-Chloromethyl-N-[4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide Ilutinib Methylxanthate Impurity C Ibrutinib Impurity D N-(3-GUANIDINO-4-METHYLPHENYL)-4-(METHYLPIPERAZINE-1-YL-METHYL)BENZAMIDE

(2E)-3-(DiMethylaMino)-1-(pyridin-3-yl)prop-2-en-1-one

(2E)-3-(DiMethylaMino)-1-(3-pyridyl)prop-2-en-1-one (IMpurity of Nilotinib)

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one

(E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one

Imatinib EP Impurity A (Nilotinib Impurity 16)

Nilotinib Impurity 16 (Imatinib EP Impurity A)

Imatinib impurity 14/(E)-3-(dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one

(E)-3-(dimethylamino)

Nilotinib IMpurity ((2E)-3-(DiMethylaMino)-1-(3-pyridyl)prop-2-en-1-one)

Irutinib Impurity A

Imatinib impurity J

2-Propen-1-one, 3-(dimethylamino)-1-(3-pyridinyl)-, (2E)-

(E)-3-(Dimethylamino)-1-(3-pyridyl)-2-propen-1-one

Imatinib EP impuritiesA

Imatinib Mesilate Impurity A

(2E)-3-(Dimethylamino)-1-(3-Pyridyl)prtop-2-en-1-one

Imatinib Mesilate EP Impurity A

123367-26-0