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Biphenylindanone A

Product Name
Biphenylindanone A
CAS No.
866823-73-6
Chemical Name
Biphenylindanone A
Synonyms
BINA;CS-203;MRLSD 230;BINA, >=98%;Biphenylindanone A;4-[3-[(2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydroinden-5-yl)oxymethyl]phenyl]benzoic acid;3'-[[(2-Cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy]methyl]biphenyl-4-carboxylic acid;3'-[[(2-Cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]-[1,1'-biphenyl]-4-carboxylicacid;[1,1'-Biphenyl]-4-carboxylic acid, 3'-[[(2-cyclopentyl-2,3-dihydro-6,7-diMethyl-1-oxo-1H-inden-5-yl)oxy]Methyl]-
CBNumber
CB72518270
Molecular Formula
C30H30O4
Formula Weight
454.56
MOL File
866823-73-6.mol
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Biphenylindanone A Property

Melting point:
238-241℃
Boiling point:
676.9±55.0 °C(Predicted)
Density 
1.220
storage temp. 
Desiccate at RT
solubility 
DMSO: ≥18mg/mL
pka
4.17±0.10(Predicted)
form 
powder
color 
white to tan
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
5.04463
Product name
BINA - CAS 866823-73-6 - Calbiochem
Packaging
5mg
Price
$257
Updated
2023/01/07
Sigma-Aldrich
Product number
B8688
Product name
Biphenyl-indanone A
Purity
≥98% (HPLC), powder
Packaging
5mg
Price
$181
Updated
2022/05/15
Sigma-Aldrich
Product number
B8688
Product name
Biphenyl-indanone A
Purity
≥98% (HPLC), powder
Packaging
25mg
Price
$694
Updated
2022/05/15
Cayman Chemical
Product number
11986
Product name
Biphenylindanone A
Purity
≥98%
Packaging
5mg
Price
$106
Updated
2024/03/01
Cayman Chemical
Product number
11986
Product name
Biphenylindanone A
Purity
≥98%
Packaging
10mg
Price
$184
Updated
2024/03/01
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Biphenylindanone A Chemical Properties,Usage,Production

Description

The metabotropic glutamate receptor 2 (mGluR2) is a Gi/o-coupled receptor which is expressed on presynaptic nerve terminals and modulates the release of neurotransmitters like glutamate and GABA. Biphenylindanone A (BINA) is a positive allosteric modulator of mGluR2, stimulating the human and rat receptors with EC50 values of 33.2 and 96 nM, respectively. It has no effect on glutamate-induced activation of other mGluR types. BINA can be used on cells, tissues, or animals. Because of its selectivity for mGluR2, robust in vivo activity, and brain penetrance, BINA can be used to elucidate the role of mGluR2 in such diverse processes as psychosis, schizophrenia, and drug addiction.

Uses

Biphenylindanone A is an orally active metabotropic glutamate subtype 2 receptor positive allosteric modulator.

Definition

ChEBI: Biphenylindanone a is a member of biphenyls.

storage

Room temperature (desiccate)

Biphenylindanone A Preparation Products And Raw materials

Raw materials

Preparation Products

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Biphenylindanone A Suppliers

Canada 1 China 42 India 1 United Kingdom 1 United States 10 Global 55
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View Lastest Price from Biphenylindanone A manufacturers

Career Henan Chemical Co
Product
Biphenylindanone A 866823-73-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
100kg
Release date
2020-01-14

866823-73-6, Biphenylindanone ARelated Search:


  • Biphenylindanone A
  • 3'-[[(2-Cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]-[1,1'-biphenyl]-4-carboxylicacid
  • BINA
  • 3'-[[(2-Cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy]methyl]biphenyl-4-carboxylic acid
  • MRLSD 230
  • 4-[3-[(2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydroinden-5-yl)oxymethyl]phenyl]benzoic acid
  • CS-203
  • [1,1'-Biphenyl]-4-carboxylic acid, 3'-[[(2-cyclopentyl-2,3-dihydro-6,7-diMethyl-1-oxo-1H-inden-5-yl)oxy]Methyl]-
  • BINA, >=98%
  • 866823-73-6
  • C30H30O4