4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid

Product Name: 4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid
CAS No.: 1082058-99-8
Chemical Name: 4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid
Synonyms: TUG 424;CAY10587;TUG-424 >=98% (HPLC);TUG-424, 10 mM in DMSO;FODHWOBAQBTTFS-UHFFFAOYSA-N;3-(4-(o-Tolylethynyl)phenyl)propanoic acid;4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid;3-(4-(o-Tolylethynyl)phenyl)propanoic acid , TUG-424;Benzenepropanoic acid, 4-[2-(2-methylphenyl)ethynyl]-
CBNumber: CB72518780
Molecular Formula: C18H16O2
Formula Weight: 264.32
MOL File: 1082058-99-8.mol

More

Less

4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid Property

Boiling point:: 448.1±38.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
storage temp.: Store at +4°C
solubility: DMSO: >10mg/mL
pka: 4.62±0.10(Predicted)
form: A crystalline solid
color: White to off-white

More

Less

Safety

Hazard Codes: Xi,N
Risk Statements: 36-50/53
Safety Statements: 26-60-61
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H319Causes serious eye irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T6829
Product name: TUG-424
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $269
Updated: 2024/03/01

Sigma-Aldrich

Product number: T6829
Product name: TUG-424
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $952
Updated: 2022/05/15

Cayman Chemical

Product number: 13143
Product name: CAY10587
Purity: ≥98%
Packaging: 1mg
Price: $33
Updated: 2024/03/01

Cayman Chemical

Product number: 13143
Product name: CAY10587
Purity: ≥98%
Packaging: 5mg
Price: $143
Updated: 2024/03/01

Cayman Chemical

Product number: 13143
Product name: CAY10587
Purity: ≥98%
Packaging: 10mg
Price: $254
Updated: 2024/03/01

More

Less

4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid Chemical Properties,Usage,Production

Biological Activity

TUG-424 is expected to be useful in the exploration of FFA1 and may also be valuable as a lead structure for new potential antidiabetic therapeutics. TUG-424 significantly increased glucose-stimulated insulin secretion at 100 nM and may serve to explore the role of FFA1 in metabolic diseases such as diabetes or obesity. It enhanced glucose-stimulated insulin secretion in a r at beta-cell line already at 100 nM and from isolated mouse islets through FFA1.

GPR40 (now FFA1) was formerly an orphan GPCR whose endogenous ligands have recently been identified as free fatty acids (FFAs). The receptor appears to be involved in the pathophysiology of type 2 diabetes and is a drug target because of its role in FFA-mediated enhancement of glucose-stimulated insulin release.

4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid Suppliers

China 31 United Kingdom 1 United States 6 Global 38

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

MQ (shanghai) Pharmaceuticals Co., Ltd.

Tel: 13761635123
Fax: 1014988033@qq
Email: 1014988033@qq.com
Country: China
ProdList: 4999
Advantage: 55

Changzhou Jiezhan Chemical Technology Co., Ltd

Tel: 15861130028; 15861130028
Email: 956912955@qq.com
Country: China
ProdList: 288
Advantage: 58

SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 13482353728
Fax: 021-61161605
Email: sales@fdc-chemical.com
Country: China
ProdList: 15006
Advantage: 58

Shanghai alkynechem Co., Ltd.

Tel: 086-021-15821262312 15821262312
Email: info@alkynechem.com
Country: China
ProdList: 1977
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44807
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 62075
Advantage: 58

Shanghai Zhongzechuan Pharmaceutical Technology Co., LTD

Tel: 15021253307
Email: sales@wesyntech.com
Country: China
ProdList: 415
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

Suzhou Zhixin Biotechnology Co., Ltd.

Tel: 0512-65118909 15162312715
Email: sales@szzxbio.com
Country: China
ProdList: 2993
Advantage: 58

Nantong QuanYi Biotechnology Co., Ltd

Tel: 0513-66337626 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 5127
Advantage: 58

Suzhou Haiben Pharmaceutical Co., Ltd

Tel: 14760821013 13564957716
Email: 1816280386@qq.com
Country: China
ProdList: 8045
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd

Tel: 13915962545
Email: 2881759498@qq.com
Country: China
ProdList: 8825
Advantage: 58

Tel
Email: sangon@qq.com
Country: CHINA
ProdList: 47239
Advantage: 58

Neobioscience Co., Ltd.

Tel: --
Fax: --
Email: info@neobioscience.com
Country: CHINA
ProdList: 6682
Advantage: 58

Proteintech China

Tel: --
Fax: --
Email: Proteintech-CN@ptglab.com
Country: CHINA
ProdList: 6290
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

Shanghai Haoran Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 470003480@QQ.COM
Country: CHINA
ProdList: 6955
Advantage: 58

Beijing Dongge Boye Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1861586486@qq.com
Country: CHINA
ProdList: 6648
Advantage: 58

Beijing Shengke Boyuan Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 978560024@qq.com
Country: CHINA
ProdList: 6005
Advantage: 58

Resenbio

Tel: --
Fax: --
Email: sales@xarxbio.com
Country: China
ProdList: 1774
Advantage: 50

Shenzhen Xinbosheng Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: service@neobioscience.com
Country: CHINA
ProdList: 6151
Advantage: 58

Morning Student Science and Technology (Guangzhou) Co., Ltd.

Tel: --
Fax: --
Email: chenxue_gz@163.com
Country: CHINA
ProdList: 6600
Advantage: 58

Shanghai Yaoyun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: 912529879@qq.com
Country: CHINA
ProdList: 6835
Advantage: 58

Shanghai Ziqi Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: 2453006496@qq.com
Country: CHINA
ProdList: 6184
Advantage: 58

Shanghai Hao Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: shxiyuanbio@163.com
Country: CHINA
ProdList: 6906
Advantage: 58

Shanghai Minmin Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1914109725@qq.com
Country: CHINA
ProdList: 6518
Advantage: 58

Beijing Bolide Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1985563437@qq.com
Country: CHINA
ProdList: 6158
Advantage: 58

Beijing Fubo Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: info@f-biology.com
Country: CHINA
ProdList: 6025
Advantage: 58

1082058-99-8, 4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacidRelated Search:

TUG 891 TUG-770 TUG-469

4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid

TUG 424

CAY10587

3-(4-(o-Tolylethynyl)phenyl)propanoic acid

FODHWOBAQBTTFS-UHFFFAOYSA-N

Benzenepropanoic acid, 4-[2-(2-methylphenyl)ethynyl]-

TUG-424 >=98% (HPLC)

3-(4-(o-Tolylethynyl)phenyl)propanoic acid , TUG-424

TUG-424, 10 mM in DMSO

1082058-99-8