ChemicalBook > CAS DataBase List > PS 48
PS 48
- Product Name
- PS 48
- CAS No.
- 1180676-32-7
- Chemical Name
- PS 48
- Synonyms
- PS 48;CS-1466;PS 48;PS-48;PS-48;PS 48;PS48;PS48 (DMSO solution), PDK1 activator;5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid;(Z)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid;(2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid;2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2Z)-;PS48, Allosteric phosphoinositide-dependent protein kinase-1 (PDK1) agonist
- CBNumber
- CB72518801
- Molecular Formula
- C17H15ClO2
- Formula Weight
- 286.75
- MOL File
- 1180676-32-7.mol
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PS 48 Property
- Melting point:
- 114-115℃
- Boiling point:
- 444.1±24.0 °C(Predicted)
- Density
- 1.225±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: >20mg/mL
- form
- powder
- pka
- 4.55±0.10(Predicted)
- color
- white to off-white
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Safety
- WGK Germany
- 3
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- P0022
- Product name
- PS48
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $80.4
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- P0022
- Product name
- PS48
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $538
- Updated
- 2024/03/01
TRC
- Product number
- P839688
- Product name
- PS48
- Packaging
- 10mg
- Price
- $85
- Updated
- 2021/12/16
TRC
- Product number
- P839688
- Product name
- PS48
- Packaging
- 50mg
- Price
- $280
- Updated
- 2021/12/16
Usbiological
- Product number
- 463157
- Product name
- PS 48
- Packaging
- 10mg
- Price
- $355
- Updated
- 2021/12/16
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PS 48 Chemical Properties,Usage,Production
Uses
PS 48 is a phosphoinositide-dependent protein kinase-1 (PDK1) activator.
Biochem/physiol Actions
PS48 is a PDK1 (phosphoinositide-dependent protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site. PS48 is one of only a few truly allosteric compounds targeting a regulatory binding site on a protein kinase catalytic domain that is not adjacent to or overlapping with the ATP-binding site.
PS 48 Preparation Products And Raw materials
Raw materials
Preparation Products
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PS 48 Suppliers
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- Fax
- 86-21-57758967
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- China
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- 0411-62910999 13889544652
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- China
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- 021-52996696，15000506266 15000506266
- Fax
- +86-21-52996696
- Country
- China
- ProdList
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View Lastest Price from PS 48 manufacturers
Career Henan Chemical Co
- Product
- (2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid 1180676-32-7
- Price
- US $1.00/g
- Min. Order
- 100g
- Purity
- 99%
- Supply Ability
- G/KG/T
- Release date
- 2019-12-20