AT-56

Product Name: AT-56
CAS No.: 162640-98-4
Chemical Name: AT-56
Synonyms: AT 56;CS-1414;AT56/AT-56;AT 56, >=98%;AT-56 AT-7519;4-Dibenzo[a,d]cyclohepten-5-ylidene-1-[4-(2H-tetrazol-5-yl)-butyl]-piperidine;4-Dibenzo[a,d] cyclohepten-5-ylidene-1-[4-(1H-tetrazol-5-yl) butyl] piperdine;4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(1H-tetrazol-5-yl)butyl]piperidine;4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine;Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-
CBNumber: CB72518821
Molecular Formula: C25H27N5
Formula Weight: 397.52
MOL File: 162640-98-4.mol

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AT-56 Property

Boiling point:: 620.4±65.0 °C(Predicted)
Density: 1.216±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: DMSO: soluble10mg/mL, clear
form: powder
pka: 4.99±0.10(Predicted)
color: white to beige
InChIKey: LQNGMDUIRLSESZ-UHFFFAOYSA-N
SMILES: N1(CCCCC2=NNN=N2)CC/C(=C2/C3=CC=CC=C3C=CC3=CC=CC=C3/2)/CC1

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H228Flammable solid

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0856
Product name: AT-56
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $107
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0856
Product name: AT-56
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $419
Updated: 2024/03/01

Cayman Chemical

Product number: 13160
Product name: AT-56
Purity: ≥95%
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 13160
Product name: AT-56
Purity: ≥95%
Packaging: 5mg
Price: $90
Updated: 2024/03/01

Cayman Chemical

Product number: 13160
Product name: AT-56
Purity: ≥95%
Packaging: 10mg
Price: $161
Updated: 2024/03/01

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AT-56 Chemical Properties,Usage,Production

Uses

AT-56 is an orally active inhibitor of Lipocalin-type prostaglandin D synthase.

in vitro

AT-56 (1-30 μM; 10 minutes) dose-dependently inhibits the production of PGD2 in L-PGDS-expressing human medulloblastoma TE-671 cells with an IC50 of about 3 μM.

in vivo

AT-56 (1-30 mg/kg; p.o.) suppresses the PGD2 production in the stab-wounded brain.
AT-56 (1-10 mg/kg; p.o.) suppresses the L-PGDS-mediated allergic airway inflammation in mice.
AT-56 (10 mg/kg; p.o.) exhibits Cmax (2.15 μg/ml), half-life (1.71 h) and high oral bioavailability (82%).

storage

Store at -20°C

AT-56 Preparation Products And Raw materials

Raw materials

Preparation Products

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AT-56 Suppliers

Canada 1 China 79 India 1 United Kingdom 2 United States 12 Global 95

Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd

Tel: 024-024-88590548 18341751992
Email: 757984502@qq.com
Country: China
ProdList: 891
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6175
Advantage: 58

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

UHN Shanghai Research & Development Co., Ltd.

Tel: 021-58958002 18930822973
Fax: +86 (21) 5895-8628
Email: sales@uhnshanghai.com
Country: China
ProdList: 977
Advantage: 58

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

Shanghai JiYi Biotechnology Co. Ltd.

Tel: 13621943973
Fax: -
Email: sales@shjiyipharmatech.com
Country: China
ProdList: 1166
Advantage: 55

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View Lastest Price from AT-56 manufacturers

Career Henan Chemical Co

Product: 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine 162640-98-4
Price: US $5.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-09-03

162640-98-4, AT-56Related Search:

AT56/AT-56

4-(DIBENZO[1,2-A:1',2'-E][7]ANNULEN-11-YLIDENE)-1-[4-(2H-TETRAZOL-5-YL)BUTYL]PIPERIDINE

4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(1H-tetrazol-5-yl)butyl]piperidine

4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine

AT 56

4-Dibenzo[a,d]cyclohepten-5-ylidene-1-[4-(2H-tetrazol-5-yl)-butyl]-piperidine

AT 56, >=98%

CS-1414

Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-

4-Dibenzo[a,d] cyclohepten-5-ylidene-1-[4-(1H-tetrazol-5-yl) butyl] piperdine

AT-56 AT-7519

Lipocalin-type,L-PGDS,synthase,prostaglandin,Inhibitor,AT56,PGE synthase,inflammatory,AT 56,Prostaglandin E synthase,drowsiness,inhibit,AT-56

162640-98-4

C25H27N5

Inhibitors