ChemicalBook > CAS DataBase List > AT-56

AT-56

Product Name
AT-56
CAS No.
162640-98-4
Chemical Name
AT-56
Synonyms
AT 56;CS-1414;AT56/AT-56;AT 56, >=98%;AT-56 AT-7519;4-Dibenzo[a,d]cyclohepten-5-ylidene-1-[4-(2H-tetrazol-5-yl)-butyl]-piperidine;4-Dibenzo[a,d] cyclohepten-5-ylidene-1-[4-(1H-tetrazol-5-yl) butyl] piperdine;4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(1H-tetrazol-5-yl)butyl]piperidine;4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine;Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-
CBNumber
CB72518821
Molecular Formula
C25H27N5
Formula Weight
397.52
MOL File
162640-98-4.mol
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AT-56 Property

Boiling point:
620.4±65.0 °C(Predicted)
Density 
1.216±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO: soluble10mg/mL, clear
form 
powder
pka
4.99±0.10(Predicted)
color 
white to beige
InChIKey
LQNGMDUIRLSESZ-UHFFFAOYSA-N
SMILES
N1(CCCCC2=NNN=N2)CC/C(=C2/C3=CC=CC=C3C=CC3=CC=CC=C3/2)/CC1
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H228Flammable solid

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0856
Product name
AT-56
Purity
≥98% (HPLC)
Packaging
5mg
Price
$107
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0856
Product name
AT-56
Purity
≥98% (HPLC)
Packaging
25mg
Price
$419
Updated
2024/03/01
Cayman Chemical
Product number
13160
Product name
AT-56
Purity
≥95%
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
13160
Product name
AT-56
Purity
≥95%
Packaging
5mg
Price
$90
Updated
2024/03/01
Cayman Chemical
Product number
13160
Product name
AT-56
Purity
≥95%
Packaging
10mg
Price
$161
Updated
2024/03/01
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AT-56 Chemical Properties,Usage,Production

Uses

AT-56 is an orally active inhibitor of Lipocalin-type prostaglandin D synthase.

in vitro

AT-56 (1-30 μM; 10 minutes) dose-dependently inhibits the production of PGD2 in L-PGDS-expressing human medulloblastoma TE-671 cells with an IC50 of about 3 μM.

in vivo

AT-56 (1-30 mg/kg; p.o.) suppresses the PGD2 production in the stab-wounded brain.
AT-56 (1-10 mg/kg; p.o.) suppresses the L-PGDS-mediated allergic airway inflammation in mice.
AT-56 (10 mg/kg; p.o.) exhibits Cmax (2.15 μg/ml), half-life (1.71 h) and high oral bioavailability (82%).

storage

Store at -20°C

AT-56 Preparation Products And Raw materials

Raw materials

Preparation Products

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AT-56 Suppliers

AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2782
Advantage
58
Target molecule Corp.
Tel
857-239-0968
Fax
857-239-8801
Email
service1@targetmol.com
Country
United States
ProdList
2559
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32080
Advantage
58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
ApexBio Technology
Tel
--
Fax
--
Email
sales@apexbt.com
Country
United States
ProdList
6251
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Santa Cruz Biotechnology, Inc.
Tel
--
Fax
--
Email
scbt@scbt.com
Country
United States
ProdList
3597
Advantage
60
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View Lastest Price from AT-56 manufacturers

Career Henan Chemical Co
Product
4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine 162640-98-4
Price
US $5.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1ton
Release date
2019-09-03

162640-98-4, AT-56Related Search:


  • AT56/AT-56
  • 4-(DIBENZO[1,2-A:1',2'-E][7]ANNULEN-11-YLIDENE)-1-[4-(2H-TETRAZOL-5-YL)BUTYL]PIPERIDINE
  • 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(1H-tetrazol-5-yl)butyl]piperidine
  • 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine
  • AT 56
  • 4-Dibenzo[a,d]cyclohepten-5-ylidene-1-[4-(2H-tetrazol-5-yl)-butyl]-piperidine
  • AT 56, >=98%
  • CS-1414
  • Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-
  • 4-Dibenzo[a,d] cyclohepten-5-ylidene-1-[4-(1H-tetrazol-5-yl) butyl] piperdine
  • AT-56 AT-7519
  • Lipocalin-type,L-PGDS,synthase,prostaglandin,Inhibitor,AT56,PGE synthase,inflammatory,AT 56,Prostaglandin E synthase,drowsiness,inhibit,AT-56
  • 162640-98-4
  • C25H27N5
  • Inhibitors