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Prolactin-Releasing Peptide (1-31) (human)

Product Name
Prolactin-Releasing Peptide (1-31) (human)
CAS No.
215510-22-8
Chemical Name
Prolactin-Releasing Peptide (1-31) (human)
Synonyms
Human PrRP-31;PrRP31 (huMan), Preprolactin (23-53) (huMan);H-Ser-Arg-Thr-His-Arg-His-Ser-Met-Glu-Ile-Arg-Thr-Pro-Asp-Ile-Asn-Pro-Ala-Trp-Tyr-Ala-Ser-Arg-Gly-Ile-Arg-Pro-Val-Gly-Arg-Phe-NH2
CBNumber
CB72524907
Molecular Formula
C160H252N56O42S
Formula Weight
3664.12788
MOL File
215510-22-8.mol
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Prolactin-Releasing Peptide (1-31) (human) Property

solubility 
Water: 1 mg/ml
form 
A lyophilized powder
color 
White to off-white
Sequence
Ser-Arg-Thr-His-Arg-His-Ser-Met-Glu-Ile-Arg-Thr-Pro-Asp-Ile-Asn-Pro-Ala-Trp-Tyr-Ala-Ser-Arg-Gly-Ile-Arg-Pro-Val-Gly-Arg-Phe-NH2
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
24986
Product name
Prolactin-Releasing Peptide (1-31) (human)
Purity
≥95%
Packaging
500μg
Price
$364
Updated
2024/03/01
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Prolactin-Releasing Peptide (1-31) (human) Chemical Properties,Usage,Production

Uses

Prolactin Releasing Peptide (1-31), human is a high affinity GPR10 ligand that cause the release of the prolactin. Prolactin Releasing Peptide (1-31) binds to GPR10 for human and rats with Ki values of 1.03 nM and 0.33 nM, respectively. Prolactin Releasing Peptide (1-31) can be used for the research of the hypothalamo-pituitary axis[1][2].

in vivo

Prolactin Releasing Peptide (1-31) (human) (ICV, 5 nM) increases plasma FSH, total plasma testosterone and significantly increased the release of LHRH from hypothalamic explants in vitro[2].
Prolactin Releasing Peptide (1-31) (human) (ICV, 100 nM) increases the hypothalanic peptides involved in the control of pituitary hormone release, vasoactive intestinal peptide (VIP) and galanin but had no effect on orexin A secretion[2].

References

[1] Langmead CJ, et al. Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor. Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor. DOI:10.1038/sj.bjp.0703617
[2] L J Seal, et al. Prolactin releasing peptide (PrRP) stimulates luteinizing hormone (LH) and follicle stimulating hormone (FSH) via a hypothalamic mechanism in male rats. Endocrinology. 2000 May;141(5):1909-12. DOI:10.1210/endo.141.5.7528

Prolactin-Releasing Peptide (1-31) (human) Preparation Products And Raw materials

Raw materials

Preparation Products

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215510-22-8, Prolactin-Releasing Peptide (1-31) (human)Related Search:

Prolactin Releasing Peptide (12-31), human Prolactin-Releasing Peptide (12-31), rat PROLACTIN,HUMAN,RECOMBINANT Prolactin Releasing Peptide (1-31), HumanPrRP-31 Prolactin, Mouse, Recombinant Prolactin, rat recombinant Prokineticin-2, Human, Recombinant H-THR-PRO-ASP-ILE-ASN-PRO-ALA-TRP-TYR-ALA-GLY-ARG-GLY-ILE-ARG-PRO-VAL-GLY-ARG-PHE-NH2 H-SER-ARG-ALA-HIS-GLN-HIS-SER-MET-GLU-ILE-ARG-THR-PRO-ASP-ILE-ASN-PRO-ALA-TRP-TYR-ALA-GLY-ARG-GLY-ILE-ARG-PRO-VAL-GLY-ARG-PHE-NH2 H-SER-ARG-ALA-HIS-GLN-HIS-SER-MET-GLU-THR-ARG-THR-PRO-ASP-ILE-ASN-PRO-ALA-TRP-TYR-THR-GLY-ARG-GLY-ILE-ARG-PRO-VAL-GLY-ARG-PHE-NH2

  • H-Ser-Arg-Thr-His-Arg-His-Ser-Met-Glu-Ile-Arg-Thr-Pro-Asp-Ile-Asn-Pro-Ala-Trp-Tyr-Ala-Ser-Arg-Gly-Ile-Arg-Pro-Val-Gly-Arg-Phe-NH2
  • PrRP31 (huMan), Preprolactin (23-53) (huMan)
  • Human PrRP-31
  • 215510-22-8