(5S)-5-methylmorpholin-3-one
- Product Name
- (5S)-5-methylmorpholin-3-one
- CAS No.
- 119844-66-5
- Chemical Name
- (5S)-5-methylmorpholin-3-one
- Synonyms
- (S)-5-MethylMorpholin-3-one;(S)-5-Methyl-3-morpholinone;(5S)-5-Methyl-3-Morpholinone;(5S)-5-methylmorpholin-3-one;3-Morpholinone, 5-methyl-, (5S)-;(S)-5-Methyl-3-morpholinone,99%e.e.;(5S)-5-methylmorpholin-3-one - [M17372]
- CBNumber
- CB72525414
- Molecular Formula
- C5H9NO2
- Formula Weight
- 115.13
- MOL File
- 119844-66-5.mol
(5S)-5-methylmorpholin-3-one Property
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- Z8132
- Product name
- (5S)-5-Methylmorpholin-3-one
- Packaging
- 250mg
- Price
- $147
- Updated
- 2021/12/16
- Product number
- AS74670-5S
- Product name
- (S)-5-Methyl-morpholin-3-one
- Purity
- 98% ee
- Packaging
- 1g
- Price
- $216
- Updated
- 2021/12/16
- Product number
- CCH0033386
- Product name
- (S)-5-METHYLMORPHOLIN-3-ONE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $228.9
- Updated
- 2021/12/16
- Product number
- Z8132
- Product name
- (5S)-5-Methylmorpholin-3-one
- Packaging
- 1g
- Price
- $290
- Updated
- 2021/12/16
- Product number
- AS74670-5S
- Product name
- (S)-5-Methyl-morpholin-3-one
- Purity
- 98% ee
- Packaging
- 5G
- Price
- $555
- Updated
- 2021/12/16
(5S)-5-methylmorpholin-3-one Chemical Properties,Usage,Production
Synthesis
94193-79-0
119844-66-5
Step 3: Synthesis of (S)-5-methylmorpholin-3-one (116): compound (3) (145 g) was dissolved in dichloromethane (2000 mL) in a 5.0 L round-bottomed flask at 0 °C. Subsequently, potassium tert-butanol (430 g, 4.0 eq.) dissolved in isopropanol (1600 mL) was added drop-wise at the same temperature and the reaction mixture was stirred for 1 hour at 0 °C. Upon completion of the reaction, the pH of the reaction mixture was adjusted to 7-8 with concentrated hydrochloric acid (180-200 mL) and the temperature was maintained at 0 °C. Next, isopropanol was removed by evaporation on a rotary evaporator and extracted with dichloromethane (1000 mL x 3). The organic layers were combined, dried with anhydrous sodium sulfate and finally concentrated to give the target product (88 g, 80% yield). The analytical data of the product were as follows:'HNMR (300 MHz, CDCl3), δ 6.75 (broad peak, 1H), 4.21-4.06 (multiple peaks, 2H), 3.91-3.86 (multiple peaks, 1H), 3.71 (multiple peaks, 1H), 3.35 (multiple peaks, 1H), 1.19 (double peaks, J=6.0 Hz, 3H); ESIMS: 116 (M+1).
References
[1] Patent: WO2014/16849, 2014, A2. Location in patent: Page/Page column 126; 127
[2] Journal of Agricultural and Food Chemistry, 2001, vol. 49, # 1, p. 138 - 141
[3] Synthesis (Germany), 2014, vol. 46,
(5S)-5-methylmorpholin-3-one Preparation Products And Raw materials
Raw materials
Preparation Products
(5S)-5-methylmorpholin-3-one Suppliers
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