(5R)-5-methylmorpholin-3-one
- Product Name
- (5R)-5-methylmorpholin-3-one
- CAS No.
- 119844-67-6
- Chemical Name
- (5R)-5-methylmorpholin-3-one
- Synonyms
- (R)-5-Methyl-3-morpholinone;(R)-5-Methylmorpholin-3-one;(5R)-5-Methyl-3-Morpholinone;(5R)-5-methylmorpholin-3-one;3-Morpholinone, 5-methyl-, (5R)-;(R)-5-Methyl-3-morpholinone,99%e.e.
- CBNumber
- CB72525429
- Molecular Formula
- C5H9NO2
- Formula Weight
- 115.13
- MOL File
- 119844-67-6.mol
(5R)-5-methylmorpholin-3-one Property
- storage temp.
- 2-8°C
- Appearance
- Off-white to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M221265
- Product name
- (R)-5-Methylmorpholin-3-one
- Packaging
- 50mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- M221265
- Product name
- (R)-5-Methylmorpholin-3-one
- Packaging
- 100mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 3435AA
- Product name
- (R)-5-Methylmorpholin-3-one
- Packaging
- 1g
- Price
- $347
- Updated
- 2021/12/16
- Product number
- 174264
- Product name
- (5R)-5-Methyl-3-morpholinone
- Packaging
- 1g
- Price
- $540
- Updated
- 2021/12/16
- Product number
- AS74670-5R
- Product name
- (R)-5-Methyl-morpholin-3-one
- Purity
- 95% ee
- Packaging
- 1g
- Price
- $252
- Updated
- 2021/12/16
(5R)-5-methylmorpholin-3-one Chemical Properties,Usage,Production
Synthesis
35320-23-1
542-58-5
119844-67-6
1. Sodium hydride (55%, 0.820 g) was slowly added to a solution of (2R)-2-amino-1-propanol (1.33 mL) in tetrahydrofuran (200 mL) at room temperature and the reaction mixture was stirred for 35 minutes. 2. Chloroethyl acetate (1.80 mL) was added dropwise to the reaction system over a period of 5 minutes at the same temperature and stirring was continued for 25 minutes. 3. The reaction mixture was heated to reflux and held for 17.5 hours. 4. Upon completion of the reaction, the mixture was allowed to cool to room temperature in air, followed by filtration. 5. The solvent in the filtrate was removed by evaporation under reduced pressure to give the crude product. 6. The crude product was purified using silica gel column chromatography (eluent: ethyl acetate/hexane) to afford (5R)-5-methyl-3-morpholinone (0.520 g, 26% yield) as an oily product.
References
[1] Patent: EP1785418, 2007, A1. Location in patent: Page/Page column 149
(5R)-5-methylmorpholin-3-one Preparation Products And Raw materials
Raw materials
Preparation Products
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