1H-Pyrazole-3-carboxylic acid, 4-phenyl-, ethyl ester
- Product Name
- 1H-Pyrazole-3-carboxylic acid, 4-phenyl-, ethyl ester
- CAS No.
- 6963-62-8
- Chemical Name
- 1H-Pyrazole-3-carboxylic acid, 4-phenyl-, ethyl ester
- Synonyms
- NSC 55495;Ethyl 4-Phenylpyrazole-3-carboxylate;ethyl 4-phenyl-1H-pyrazole-5-carboxylate;Ethyl 4-phenyl-1H-pyrazole-3-carboxylate;1H-Pyrazole-3-carboxylic acid, 4-phenyl-, ethyl ester
- CBNumber
- CB72548572
- Molecular Formula
- C12H12N2O2
- Formula Weight
- 216.24
- MOL File
- 6963-62-8.mol
1H-Pyrazole-3-carboxylic acid, 4-phenyl-, ethyl ester Property
- Melting point:
- 164-165℃
- Boiling point:
- 428.5±38.0 °C(Predicted)
- Density
- 1.196±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 10.98±0.50(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CHM0314778
- Product name
- 4-PHENYL-1H-PYRAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.62
- Updated
- 2021/12/16
- Product number
- 0759AC
- Product name
- Ethyl4-phenyl-1H-pyrazole-3-carboxylate
- Packaging
- 10g
- Price
- $2075
- Updated
- 2021/12/16
- Product number
- 0759AC
- Product name
- Ethyl4-phenyl-1H-pyrazole-3-carboxylate
- Packaging
- 25g
- Price
- $3425
- Updated
- 2021/12/16
- Product number
- A232247
- Product name
- Ethyl4-phenyl-1H-pyrazole-3-carboxylate
- Purity
- 97%
- Packaging
- 100mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- CM128806
- Product name
- ethyl4-phenyl-1H-pyrazole-3-carboxylate
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $112
- Updated
- 2021/12/16
1H-Pyrazole-3-carboxylic acid, 4-phenyl-, ethyl ester Chemical Properties,Usage,Production
Synthesis
5292-53-5
6963-62-8
General procedure for the synthesis of ethyl 4-phenyl-1H-pyrazole-3-carboxylate from diethyl benzylidene malonate: in a 10 mL microwave glass vial, EtOH (1 mL) and pyrazolidine 6 (0.1 mmol) were added, followed by Cs2CO3 (16.5 mg, 0.05 mmol, 0.5 equiv). The reaction mixture was placed in a microwave reactor and radiated at 80°C for 10-15 min and the reaction progress was monitored by TLC. Upon completion of the reaction, EtOH was removed under vacuum. the residue was treated with 10 mL of water and the aqueous phase was extracted with EtOAc (2 × 10 mL). The organic phases were combined, dried with anhydrous Na2SO4, filtered and the filtrate was concentrated under vacuum. The residue was recrystallized by EtOAc/hexane (1:1) mixed solvent to give pure ethyl 4-phenyl-1H-pyrazole-3-carboxylate (compound 5) in quantitative yield.
References
[1] Tetrahedron, 2018, vol. 74, # 22, p. 2716 - 2724
1H-Pyrazole-3-carboxylic acid, 4-phenyl-, ethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Pyrazole-3-carboxylic acid, 4-phenyl-, ethyl ester Suppliers
- Tel
- --
- Fax
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- enquiries@fluorochem.co.uk
- Country
- United Kingdom
- ProdList
- 6401
- Advantage
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View Lastest Price from 1H-Pyrazole-3-carboxylic acid, 4-phenyl-, ethyl ester manufacturers
- Product
- 1H-Pyrazole-3-carboxylic acid, 4-phenyl-, ethyl ester 6963-62-8
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-01-12