2,5,6-trichloronicotinaMide
- Product Name
- 2,5,6-trichloronicotinaMide
- CAS No.
- 142266-62-4
- Chemical Name
- 2,5,6-trichloronicotinaMide
- Synonyms
- 2,5,6-trichloronicotinaMide;2,5,6-Trichloro-nicotineamide;2,5,6-Trichloropyridin-3-carboxamide;2,5,6-Trichloro-3-pyridinecarboxaMide;2,5,6-trichloropyridine-3-carboxamide;3-Pyridinecarboxamide, 2,5,6-trichloro-
- CBNumber
- CB72549443
- Molecular Formula
- C6H3Cl3N2O
- Formula Weight
- 225.46
- MOL File
- 142266-62-4.mol
2,5,6-trichloronicotinaMide Property
- Boiling point:
- 290.0±40.0 °C(Predicted)
- Density
- 1.643±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 13.32±0.50(Predicted)
- Appearance
- White to off-white Solid
N-Bromosuccinimide Price
- Product number
- 6947AA
- Product name
- 2,5,6-Trichloronicotinamide
- Packaging
- 100mg
- Price
- $201
- Updated
- 2021/12/16
- Product number
- 6947AA
- Product name
- 2,5,6-Trichloronicotinamide
- Packaging
- 250mg
- Price
- $257
- Updated
- 2021/12/16
- Product number
- HCH0362797
- Product name
- 2,5,6-TRICHLORONICOTINAMIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.89
- Updated
- 2021/12/16
- Product number
- 179556
- Product name
- 2,5,6-Trichloronicotinamide
- Packaging
- 1g
- Price
- $826
- Updated
- 2021/12/16
- Product number
- 179556
- Product name
- 2,5,6-Trichloronicotinamide
- Packaging
- 5g
- Price
- $1650
- Updated
- 2021/12/16
2,5,6-trichloronicotinaMide Chemical Properties,Usage,Production
Synthesis
58584-88-6
142266-62-4
General procedure for the synthesis of 2,5,6-trichloropyridin-3-amide from 2,5,6-trichloronicotinoyl chloride: a solution of dioxane (20 ml) of 2,5,6-trichloronicotinoyl chloride (2.5 g, 10.2 mmol) was slowly added dropwise to 10 ml of ammonium hydroxide (28% NH3 aqueous solution) at 0 °C. After the dropwise addition, the reaction mixture was continued to be stirred at 0°C for 10 min. Subsequently, extraction was carried out with dichloromethane (3 x 50 ml). All organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford 2,5,6-trichloropyridin-3-amide (2.3 g, 100% yield), which could be used in subsequent reactions without further purification.
References
[1] Patent: WO2006/82392, 2006, A1. Location in patent: Page/Page column 109
[2] Bioorganic and Medicinal Chemistry, 2002, vol. 10, # 6, p. 1793 - 1804
[3] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 10, p. 2958 - 2961
2,5,6-trichloronicotinaMide Preparation Products And Raw materials
Raw materials
Preparation Products
2,5,6-trichloronicotinaMide Suppliers
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