5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indoline
- Product Name
- 5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indoline
- CAS No.
- 1062174-44-0
- Chemical Name
- 5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indoline
- Synonyms
- Indoline-5-boronic Acid Pinacol Ester;INDOLIN-5-YLBORONIC ACID PINACOL ESTER;5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indoline;5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-indole;1H-Indole, 2,3-dihydro-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-
- CBNumber
- CB72549791
- Molecular Formula
- C14H20BNO2
- Formula Weight
- 245.13
- MOL File
- 1062174-44-0.mol
5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indoline Property
- Boiling point:
- 372.7±31.0 °C(Predicted)
- Density
- 1.08±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 4.59±0.20(Predicted)
- Appearance
- White to yellow Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T305745
- Product name
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indoline
- Packaging
- 100mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- X8796
- Product name
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indoline
- Packaging
- 250mg
- Price
- $277
- Updated
- 2021/12/16
- Product number
- BOR0006939
- Product name
- 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)INDOLINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.32
- Updated
- 2021/12/16
- Product number
- OR305261
- Product name
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-indole
- Packaging
- 250mg
- Price
- $507
- Updated
- 2021/12/16
- Product number
- 076396
- Product name
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indoline
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $786
- Updated
- 2021/12/16
5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indoline Chemical Properties,Usage,Production
Synthesis
837392-67-3
1062174-44-0
Step 3: tert-butyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)dihydroindole-1-carboxylate (120 mg, 0.35 mmol) was dissolved in dichloromethane (5 mL), 2,2,2-trifluoroacetic acid (1 mL) was added, and the reaction mixture was stirred for 2 hours at room temperature. After the reaction was completed, it was neutralized with saturated aqueous sodium bicarbonate solution to pH=8 and then extracted with dichloromethane. The organic phases were combined, washed with brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford the target product 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)dihydroindole (74 mg, 87% yield).1H NMR (CDCl3) δ: 7.56 (1H, s), 7.50 (1H, d, J = 8.0 Hz), 6.60 (1H, d, J = 8.0 Hz), 3.57 (2H, t, J = 8.8 Hz), 3.02 (2H, t, J = 8.8 Hz), 1.32 (12H, s).
References
[1] Patent: WO2012/103806, 2012, A1. Location in patent: Page/Page column 48
5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indoline Preparation Products And Raw materials
Raw materials
Preparation Products
5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indoline Suppliers
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