6-Fluoro-1H-pyrrolo[3,2-b]pyridine
- Product Name
- 6-Fluoro-1H-pyrrolo[3,2-b]pyridine
- CAS No.
- 1190320-33-2
- Chemical Name
- 6-Fluoro-1H-pyrrolo[3,2-b]pyridine
- Synonyms
- 6-Fluoro-4-azaindole;6-Fluoro-1H-pyrrolo[3,2-b]pyridine;1H-Pyrrolo[3,2-b]pyridine, 6-fluoro-
- CBNumber
- CB72550160
- Molecular Formula
- C7H5FN2
- Formula Weight
- 136.13
- MOL File
- 1190320-33-2.mol
6-Fluoro-1H-pyrrolo[3,2-b]pyridine Property
- Boiling point:
- 277.6±20.0 °C(Predicted)
- Density
- 1.370±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 14.06±0.40(Predicted)
- Appearance
- White to light brown Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- F593143
- Product name
- 6-Fluoro-1H-pyrrolo[3,2-b]pyridine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- PC56323
- Product name
- 6-Fluoro-1H-pyrrolo[3,2-b]pyridine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- 3237AA
- Product name
- 6-Fluoro-1H-pyrrolo[3,2-b]pyridine
- Packaging
- 100mg
- Price
- $184
- Updated
- 2021/12/16
- Product number
- 3H31-3-5W
- Product name
- 6-Fluoro-1H-pyrrolo[3,2-b]pyridine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- PC56323
- Product name
- 6-Fluoro-1H-pyrrolo[3,2-b]pyridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $425
- Updated
- 2021/12/16
6-Fluoro-1H-pyrrolo[3,2-b]pyridine Chemical Properties,Usage,Production
Synthesis
1445856-41-6
1190320-33-2
Step 3: To a solution of 5-fluoro-2-((trimethylsilyl)alkynyl)pyridin-3-amine (2.22 g, 10.7 mmol) in N,N-dimethylformamide (DMF, 30 mL) was added sodium hydride (60% Mineral Oil Dispersion, 1.025 g, 42.7 mmol) in one batch at 0 °C and under nitrogen protection. After addition, the reaction mixture was stirred at room temperature for 2 hours. Subsequently, the reaction solution was slowly poured into ice water and extracted with ethyl acetate (EtOAc). The organic phases were combined, dried over anhydrous magnesium sulfate (MgSO?), filtered and concentrated under reduced pressure to give 1.46 g of 6-fluoro-1H-pyrrolo[3,2-b]pyridine as a brown solid (100% yield). Mass spectrum (ESI): m/z = 137.2 [M + H]?
References
[1] Patent: WO2013/92940, 2013, A1. Location in patent: Page/Page column 51
[2] Patent: WO2016/103037, 2016, A1. Location in patent: Paragraph 00631
6-Fluoro-1H-pyrrolo[3,2-b]pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
6-Fluoro-1H-pyrrolo[3,2-b]pyridine Suppliers
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View Lastest Price from 6-Fluoro-1H-pyrrolo[3,2-b]pyridine manufacturers
- Product
- 6-Fluoro-1H-pyrrolo[3,2-b]pyridine 1190320-33-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-09