5-Morpholinopicolinic acid
- Product Name
- 5-Morpholinopicolinic acid
- CAS No.
- 1072103-29-7
- Chemical Name
- 5-Morpholinopicolinic acid
- Synonyms
- 5-Morpholinopicolinic acid;5-morpholin-4-ylpyridine-2-carboxylic acid;5-(4-Morpholinyl)-2-pyridinecarboxylic acid;2-Pyridinecarboxylic acid, 5-(4-morpholinyl)-
- CBNumber
- CB72552270
- Molecular Formula
- C10H12N2O3
- Formula Weight
- 208.21
- MOL File
- 1072103-29-7.mol
5-Morpholinopicolinic acid Property
- Boiling point:
- 446.1±45.0 °C(Predicted)
- Density
- 1.313±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 0.86±0.50(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-0060454
- Product name
- 5-Morpholinopicolinicacid
- Purity
- 99.62%
- Packaging
- 100mg
- Price
- $97
- Updated
- 2021/12/16
- Product number
- CS-0060454
- Product name
- 5-Morpholinopicolinicacid
- Purity
- 99.62%
- Packaging
- 250mg
- Price
- $177
- Updated
- 2021/12/16
- Product number
- CS-0060454
- Product name
- 5-Morpholinopicolinicacid
- Purity
- 99.62%
- Packaging
- 1g
- Price
- $444
- Updated
- 2021/12/16
- Product number
- CHM0390965
- Product name
- 5-MORPHOLINOPICOLINIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.43
- Updated
- 2021/12/16
- Product number
- CS-0060454
- Product name
- 5-Morpholinopicolinicacid
- Purity
- 99.62%
- Packaging
- 50mg
- Price
- $75
- Updated
- 2021/12/16
5-Morpholinopicolinic acid Chemical Properties,Usage,Production
Synthesis
1301214-68-5
1072103-29-7
4-[6-(piperidin-1-ylcarbonyl)pyridin-3-yl]morpholine (18.3 g) was added to 25% aqueous KOH solution (100 mL) and the mixture was heated to reflux. After the reaction was completed, the reaction solution was neutralized with HCl. Subsequently, the solution was concentrated under reduced pressure to remove the solvent. The product was purified by hot isopropanol extraction to give finally (5-morpholin-4-yl)pyridine-2-carboxylic acid (11.5 g, 71% yield). The product was detected by ESI MS and showed [M+H]+ peak of 209.7; 1H NMR (400 MHz, DMSO-d6) δ ppm: 8.34 (br.s, 1H), 8.03 (d, 1H), 7.65 (dd, 1H), 3.75 (br.s, 4H), 3.40 (br.s, 4H).
References
[1] Patent: US2011/111046, 2011, A1. Location in patent: Page/Page column 15
[2] Patent: WO2011/58473, 2011, A1. Location in patent: Page/Page column 30
5-Morpholinopicolinic acid Preparation Products And Raw materials
Raw materials
Preparation Products
5-Morpholinopicolinic acid Suppliers
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