ChemicalBook > CAS DataBase List > Cyclopentanol, 3-amino-, hydrochloride (1:1)

Cyclopentanol, 3-amino-, hydrochloride (1:1)

Product Name
Cyclopentanol, 3-amino-, hydrochloride (1:1)
CAS No.
1184919-69-4
Chemical Name
Cyclopentanol, 3-amino-, hydrochloride (1:1)
Synonyms
3-aminocyclopentan-1-ol hydrochloride;3-AMinocyclopentanol, HCl;3-AMINO-CYCLOPENTANOL hyd...;3-AMinocyclopentanol hydr...;3-AMinocyclopentanol hdydrochloride;3-amino-Cyclopentanol hydrochloride (1:1);Cyclopentanol, 3-amino-, hydrochloride (1:1);3-Aminocyclopentanol hydrochloride (cis-trans mixture)
CBNumber
CB72552816
Molecular Formula
C5H12ClNO
Formula Weight
137.61
MOL File
1184919-69-4.mol
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Cyclopentanol, 3-amino-, hydrochloride (1:1) Property

storage temp. 
Inert atmosphere,Room Temperature
Appearance
Colorless to off-white Solid-Liquid Mixture
InChI
InChI=1S/C5H11NO.ClH/c6-4-1-2-5(7)3-4;/h4-5,7H,1-3,6H2;1H
InChIKey
SGKRJNWIEGYWGE-UHFFFAOYSA-N
SMILES
NC1CCC(O)C1.Cl
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
warning
Hazard statements

H303May be harmfulif swallowed

H313May be harmful in contact with skin

H333May be harmful if inhaled

Precautionary statements

P304+P312IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

TRC
Product number
A615888
Product name
3-AminocyclopentanolHydrochloride
Packaging
500mg
Price
$155
Updated
2021/12/16
ChemScene
Product number
CS-W005211
Product name
3-Aminocyclopentanolhydrochloride
Packaging
250mg
Price
$55
Updated
2021/12/16
ChemScene
Product number
CS-W005211
Product name
3-Aminocyclopentanolhydrochloride
Packaging
1g
Price
$131
Updated
2021/12/16
SynQuest Laboratories
Product number
4256-5-48
Product name
3-Aminocyclopentan-1-ol hydrochloride
Purity
97.0%
Packaging
250mg
Price
$240
Updated
2021/12/16
ChemScene
Product number
CS-W005211
Product name
3-Aminocyclopentanolhydrochloride
Packaging
5g
Price
$385
Updated
2021/12/16
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Cyclopentanol, 3-amino-, hydrochloride (1:1) Chemical Properties,Usage,Production

Uses

3-Aminocyclopentanol Hydrochloride is used in preparation of oxo-pyridine fusion ring derivatives as RON inhibitors for treatment of RON-related diseases.

Synthesis

1445796-28-0

1184919-69-4

General procedure for the synthesis of 3-aminocyclopentanol hydrochloride from the compound (CAS: 1445796-28-0): concentrated hydrochloric acid (HCl, 10 mL) was slowly added to a solution of compound 4 (8.0 g, 34 mmol) in methanol (MeOH, 100 mL), and the reaction mixture was subsequently heated and refluxed for 2 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure to remove the solvent. The obtained residue was dissolved in water and washed with ethyl acetate (EA). The aqueous phase was subsequently concentrated under reduced pressure to afford the target product 3-aminocyclopentanol hydrochloride (2.8 g, 82% yield) containing the HCl salt. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3) with the following chemical shifts (δ ppm): 4.33 (broad single peak, 1H), 3.66 (broad single peak, 1H), 2.08-2.16 (multiple peaks, 2H), 1.74-1.90 (multiple peaks, 4H).

References

[1] Patent: WO2013/96744, 2013, A1. Location in patent: Page/Page column 215

Cyclopentanol, 3-amino-, hydrochloride (1:1) Preparation Products And Raw materials

Raw materials

Preparation Products

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Cyclopentanol, 3-amino-, hydrochloride (1:1) Suppliers

China 72 India 1 United States 4 Global 77
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
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View Lastest Price from Cyclopentanol, 3-amino-, hydrochloride (1:1) manufacturers

Career Henan Chemical Co
Product
3-AMINO-CYCLOPENTANOL hyd... 1184919-69-4
Price
US $9.80/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
20 tons
Release date
2020-01-10

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