GW 610

Product Name: GW 610
CAS No.: 872726-44-8
Chemical Name: GW 610
Synonyms: GW 610;NSC 721648;NSC 721648 PMX 610;NSC 721648 - CAS 872726-44-8 - Calbiochem;2-(3,4-Dimethoxyphenyl)-5-fluorobenzo[d]thiazole;Benzothiazole, 2-(3,4-dimethoxyphenyl)-5-fluoro-;GW 610,colon,Inhibitor,GW610,NSC721648,inhibit,breast,antitumor,NSC 721648,lung,GW-610,NSC-721648
CBNumber: CB72591189
Molecular Formula: C15H12FNO2S
Formula Weight: 289.3246832
MOL File: 872726-44-8.mol

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GW 610 Property

Melting point:: 110 °C
Boiling point:: 422.8±55.0 °C(Predicted)
Density: 1.293±0.06 g/cm3(Predicted)
storage temp.: +2C to +8C
solubility: DMF:10.0(Max Conc. mg/mL);34.56(Max Conc. mM)
DMF:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.86(Max Conc. mM)
DMSO:9.5(Max Conc. mg/mL);32.84(Max Conc. mM)
form: White crystalline solid
pka: 0.73±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10008313
Product name: GW 610
Purity: ≥98%
Packaging: 1mg
Price: $22
Updated: 2024/03/01

Cayman Chemical

Product number: 10008313
Product name: GW 610
Purity: ≥98%
Packaging: 5mg
Price: $95
Updated: 2024/03/01

Cayman Chemical

Product number: 10008313
Product name: GW 610
Purity: ≥98%
Packaging: 10mg
Price: $167
Updated: 2024/03/01

Cayman Chemical

Product number: 10008313
Product name: GW 610
Purity: ≥98%
Packaging: 50mg
Price: $723
Updated: 2024/03/01

TRC

Product number: G929500
Product name: GW610
Packaging: 5mg
Price: $70
Updated: 2021/12/16

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GW 610 Chemical Properties,Usage,Production

Description

GW 610 is an antitumor benzothiazole that shows growth-inhibitory activity against several cancer cell lines. In MCF-7 and MDA 468 human cancer cell lines, potent antiproliferative activity (growth inhibition (GI₅₀) < 0.1 nM) was observed. Potent and selective activity was also observed in the NCI 60 human cancer cell line panel. In contrast with previously reported 2-(4-aminophenyl)benzothiazoles, GW 610 is not reliant on induction of cytochrome P 1A1 (CYP1A1) expression for antitumor activity.

Uses

GW 610 is a fluorinated 2-arylbenzothiazole and potential antitumor drug, which shows potent and selective inhibitory activity against breast, lung, and colon cancer cell lines. Studies suggest that the species-specific partial agonism of the aryl hydrocarbon receptor shown by GW 610 plays an important role in its anti-proliferative activity.

GW 610 Preparation Products And Raw materials

Raw materials

Preparation Products

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GW 610 Suppliers

Canada 1 China 41 United States 5 Global 47

Dongying Sifang Litong New Material Co. LTD

Tel: 13589435123 17861826421
Email: dysflt@126.com
Country: China
ProdList: 287
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J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94837
Advantage: 76

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8073
Advantage: 58

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 3552
Advantage: 55

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 56056
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
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MedBioPharmaceutical Technology Inc

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Hefei Mokai Pharmaceutical Technology Co., Ltd

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Bide Pharmatech Ltd.

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Email: product02@bidepharm.com
Country: China
ProdList: 63720
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872726-44-8, GW 610Related Search:

GW 610

NSC 721648

NSC 721648 - CAS 872726-44-8 - Calbiochem

NSC 721648 PMX 610

GW 610,colon,Inhibitor,GW610,NSC721648,inhibit,breast,antitumor,NSC 721648,lung,GW-610,NSC-721648

Benzothiazole, 2-(3,4-dimethoxyphenyl)-5-fluoro-

2-(3,4-Dimethoxyphenyl)-5-fluorobenzo[d]thiazole

872726-44-8

Aromatics

Heterocycles

Inhibitors

Intermediates & Fine Chemicals

Pharmaceuticals

Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals