10,11-dihydro-5H-dibenzo[b,f]azepin-10-o
- Product Name
- 10,11-dihydro-5H-dibenzo[b,f]azepin-10-o
- CAS No.
- 4014-77-1
- Chemical Name
- 10,11-dihydro-5H-dibenzo[b,f]azepin-10-o
- Synonyms
- Licarbazepine Impurity 5;Oxcarbazepine Impurity 27;10,11-dihydro-5H-dibenzo[b,f]azepin-10-o;10,11-Dihydro-5H-dibenzo[b,f]azepin-10-ol;5H-Dibenz[b,f]azepin-10-ol, 10,11-dihydro-;6,11-dihydro-5H-benzo[b][1]benzazepin-5-ol
- CBNumber
- CB72604465
- Molecular Formula
- C14H13NO
- Formula Weight
- 211.26
- MOL File
- 4014-77-1.mol
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D458523
- Product name
- 10,11-Dihydro-5H-dibenzo[b,f]azepin-10-ol
- Packaging
- 100mg
- Price
- $330
- Updated
- 2021/12/16
- Product number
- FD141318
- Product name
- 10,11-Dihydro-5H-dibenzo[b,f]azepin-10-ol
- Packaging
- 50mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FD141318
- Product name
- 10,11-Dihydro-5H-dibenzo[b,f]azepin-10-ol
- Packaging
- 100mg
- Price
- $113
- Updated
- 2021/12/16
- Product number
- FD141318
- Product name
- 10,11-Dihydro-5H-dibenzo[b,f]azepin-10-ol
- Packaging
- 250mg
- Price
- $225
- Updated
- 2021/12/16
- Product number
- FD141318
- Product name
- 10,11-Dihydro-5H-dibenzo[b,f]azepin-10-ol
- Packaging
- 500mg
- Price
- $390
- Updated
- 2021/12/16
10,11-dihydro-5H-dibenzo[b,f]azepin-10-o Chemical Properties,Usage,Production
Synthesis
21737-58-6
4014-77-1
The general procedure for the synthesis of 10,11-dihydro-5H-dibenzo[b,f]azepin-10-ol from 5H-dibenzo[b,f]azepin-10(11H)-one was as follows: 5H-dibenzo[b,f]azepin-10(11H)-one (350.0 g, 1.67 mol) was suspended in water (0.7 L) and methanol (2.8 L) in a mixed solvents. Sodium borohydride (76 g, 2.0 mol) was added in batches over 10 min without cooling and the reaction mixture was stirred continuously at 45 °C for 1 h. The reaction was completed by the addition of acetone (1.0 g, 2.0 mol). Upon completion of the reaction, acetone (350 mL) was added cautiously to quench the reaction and the reaction mixture was subsequently concentrated to a smaller volume. The target product was precipitated by the addition of water (700 mL) and the precipitate was collected and dried at 60-65 °C to afford (S)-10,11-dihydro-5H-dibenzo[b,f]azepin-10-ol (315 g, 89.0% yield) as an off-white solid with a purity of >98%.
References
[1] Tetrahedron Letters, 2013, vol. 54, # 22, p. 2841 - 2844
10,11-dihydro-5H-dibenzo[b,f]azepin-10-o Preparation Products And Raw materials
Raw materials
Preparation Products
10,11-dihydro-5H-dibenzo[b,f]azepin-10-o Suppliers
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- mktg@pharmaffiliates.com
- Country
- India
- ProdList
- 6739
- Advantage
- 58
- Tel
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- sales@ajchem.in
- Country
- India
- ProdList
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- Advantage
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View Lastest Price from 10,11-dihydro-5H-dibenzo[b,f]azepin-10-o manufacturers
- Product
- 10,11-dihydro-5H-dibenzo[b,f]azepin-10-o 4014-77-1
- Price
- US $1.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100000KG
- Release date
- 2024-07-26