MBX2982
- Product Name
- MBX2982
- CAS No.
- 1037792-44-1
- Chemical Name
- MBX2982
- Synonyms
- CS-485;MBX2982;SAR-260093;MBX-2982, >=98%;MBX2982 / MBX-2982;MBX-2982 (SAR260093);MBX-2982;MBX 2982;MBX2982;2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole;4-((4-(1H-Tetrazol-1-yl)phenoxy)methyl)-2-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yl)thiazole;pyrimidine, 5-ethyl-2-[4-[4-[[4-(1h-tetrazol-1-yl)phenoxy]methyl]-2-thiazolyl]-1-piperidinyl]-
- CBNumber
- CB72620009
- Molecular Formula
- C22H24N8OS
- Formula Weight
- 448.54
- MOL File
- 1037792-44-1.mol
MBX2982 Property
- Boiling point:
- 683.6±65.0 °C(Predicted)
- Density
- 1.42
- storage temp.
- Store at -20°C
- solubility
- DMSO : 50 mg/mL (111.47 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
- form
- Powder
- pka
- 5.39±0.42(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 22206
- Product name
- MBX-2982
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $153
- Updated
- 2024/03/01
- Product number
- 22206
- Product name
- MBX-2982
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $275
- Updated
- 2024/03/01
- Product number
- 22206
- Product name
- MBX-2982
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $606
- Updated
- 2024/03/01
- Product number
- 22206
- Product name
- MBX-2982
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $844
- Updated
- 2024/03/01
- Product number
- orb181053
- Product name
- MBX-2982
- Purity
- >98%
- Packaging
- 100mg
- Price
- $838.1
- Updated
- 2021/12/16
MBX2982 Chemical Properties,Usage,Production
Description
MBX-2982 is an agonist of GPR119. It reduces nuclear and total protein levels of sterol regulatory element binding protein 1 (SREBP-1) in HepG2 cells and rat primary hepatocytes under high-glucose and -insulin conditions and increases phosphorylation of the inhibitory form, SREBP-1c. MBX-2982 (10 mg/kg) inhibits hepatic lipid accumulation in wild-type, but not GPR119 knockout, mice fed a high-fat diet. It also increases plasma levels of glucagon-like peptide 1 (GLP-1; ) in mice when administered at a dose of 10 mg/kg prior to, and to a greater extent following, glucose administration. MBX-2982 increases glucokinase activity in an enzyme assay with an EC50 value of 45.11 μM.
MBX2982 Preparation Products And Raw materials
Raw materials
Preparation Products
MBX2982 Suppliers
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View Lastest Price from MBX2982 manufacturers
- Product
- MBX2982 1037792-44-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 20kg
- Release date
- 2019-12-23