ChemicalBook > CAS DataBase List > Edoxaban tosylate

Edoxaban tosylate

Product Name
Edoxaban tosylate
CAS No.
480449-71-6
Chemical Name
Edoxaban tosylate
Synonyms
DU-176b;Edoxaban TsOH;Edoxaban tosylate;Edoxaban (TsOH salt);Edoxaban p-Toluenesulfonate;Edoxaban tosylate (DU-176b);9H-FLUORENE-2,11-DICARBOXYLICACID;C24H30ClN7O4S.C7H7HSO3 Edoxaban (TsOH salt) 480449-71-6;N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide;N1-(5-Chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide 4-methylbenzenesulfonate
CBNumber
CB72627790
Molecular Formula
C24H30ClN7O4S.C7H8O3S
Formula Weight
720.26
MOL File
480449-71-6.mol
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Edoxaban tosylate Property

storage temp. 
Store at -20°C
solubility 
25℃: DMSO
form 
Powder
color 
White to off-white
InChIKey
ZLFZITWZOYXXAW-BUZWFPPCNA-N
SMILES
S(C1C=CC(C)=CC=1)(O)(=O)=O.N([C@@H]1C[C@@H](C(=O)N(C)C)CC[C@@H]1NC(=O)C(=O)NC1N=CC(Cl)=CC=1)C(C1SC2CN(C)CCC=2N=1)=O |&1:12,14,22,r|
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3263
Product name
Edoxaban tosylate
Purity
≥98% (HPLC)
Packaging
5MG
Price
$79
Updated
2022/05/15
Sigma-Aldrich
Product number
SML3263
Product name
Edoxaban tosylate
Purity
≥98% (HPLC)
Packaging
25MG
Price
$319
Updated
2022/05/15
Cayman Chemical
Product number
24030
Product name
Edoxaban (tosylate)
Purity
≥98%
Packaging
500μg
Price
$33
Updated
2024/03/01
Cayman Chemical
Product number
24030
Product name
Edoxaban (tosylate)
Purity
≥98%
Packaging
1mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
24030
Product name
Edoxaban (tosylate)
Purity
≥98%
Packaging
5mg
Price
$238
Updated
2024/03/01
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Edoxaban tosylate Chemical Properties,Usage,Production

Uses

Edoxaban tosylate (Lixiana; Daiichi Sankyo, Tokyo, Japan), known as DU-176b in clinical trials, is a novel oral direct factor Xa inhibitor. Edoxaban has good bioavailability with maximum plasma concentration achieved 1–2 h after ingestion and plasma half-life of 8–10 h. Edoxaban is a novel anticoagulant (NOAC) indicated to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis and pulmonary embolism.

Definition

ChEBI: An organosulfonate salt obtained by combining equimolar amounts of edoxaban and 4-toluenesulfonic acid. Used (in the form of its monohydrate) for the treatment of deep vein thrombosis and pulmonary embolism.

Edoxaban tosylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Edoxaban tosylate Suppliers

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View Lastest Price from Edoxaban tosylate manufacturers

Zhuhai Hairuide Bioscience and Technology Co., Ltd
Product
Edoxaban (tosylate) 480449-71-6
Price
US $0.00/kg Ton
Min. Order
1kg Ton
Purity
99%+
Supply Ability
2 tons/month
Release date
2022-10-09
Hangzhou Huarong Pharm Co., Ltd.
Product
Edoxaban tosylate 480449-71-6
Price
US $0.00-0.00/KG
Min. Order
100g
Purity
99%
Supply Ability
500KG
Release date
2021-09-15
Career Henan Chemical Co
Product
Edoxaban (TsOH salt) 480449-71-6
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2020-01-07

480449-71-6, Edoxaban tosylateRelated Search:

EthanediaMide iMpurity F EthanediaMide iMpurity F hcl Edoxaban Impurity 19 (1S,2R,4S) Mesylate lithium 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylate EthanediaMide iMpurity D Edoxaban (tosylate Monohydrate) EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1R,2S,4S)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- Tert-Butyl(1R,2S,5S)-2-azido-5-[(dimethylamino)carbonyl]cyclohexylcarbamate oxalic acid edoxaban Ethyl 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate hydrochloride tert-butyl (1R,2S,5S)-2-aMino-5-(diMethylcarbaMoyl)cyclohexylcarbaMate

  • Edoxaban TsOH
  • DU-176b
  • Edoxaban (TsOH salt)
  • Edoxaban tosylate
  • Edoxaban tosylate (DU-176b)
  • C24H30ClN7O4S.C7H7HSO3 Edoxaban (TsOH salt) 480449-71-6
  • 9H-FLUORENE-2,11-DICARBOXYLICACID
  • Edoxaban p-Toluenesulfonate
  • N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide
  • N1-(5-Chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide 4-methylbenzenesulfonate
  • N-(5-Chloropyridin-2-yl)-N′-((1S,2R,4S)-4-[(dimethyl amino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl)ethanediamide p-toluenesulfonate
  • Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonate (1:1)
  • 480449-71-6
  • 480448-71-6
  • C24H30ClN7O4SC7H7HSO3
  • C31H38ClN7O7S2
  • C24H30ClN7O4SC7H8O3S