ChemicalBook > CAS DataBase List > ANTI-MBD4
ANTI-MBD4
- Product Name
- ANTI-MBD4
- Chemical Name
- ANTI-MBD4
- Synonyms
- ANTI-MBD4;Anti-MED1;ANTI-MBD4, HUMAN;ANTI-MBD4 (268-282, 337-352) RABBIT PAB;ANTI-METHYL-CPG-BINDING DOMAIN 4, HUMAN;Anti-Methyl-CpG binding domain protein 4;Anti-MBD4 antibody produced in rabbit;ANTI-METHYL-CPG-BINDING DOMAIN 4 (268-282, 337-352) RABBIT PAB;Anti-Methyl-CpG-binding protein MBD4 antibody produced in rabbit;Anti-Methyl-CpG-binding endonuclease 1 antibody produced in rabbit
- CBNumber
- CB7263248
- Formula Weight
- 0
- MOL File
- Mol file
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ANTI-MBD4 Property
- storage temp.
- −20°C
- form
- buffered aqueous solution
- biological source
- rabbit
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Safety
- Safety Statements
- 23-24/25
- WGK Germany
- -
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ANTI-MBD4 Chemical Properties,Usage,Production
Biological Activity
MBD4 (methyl-CpG binding domain 4, DNA glycosylase) is involved in the maintenance of genomic integrity. It acts as a DNA repair protein in the DNA mismatch repair (MMR) system. During DNA repair, MBD4 couples with MMR protein MLH1 (mutL homolog 1) th at binds to the methyl-CpG-containing DNA to perform endonuclease activity. MBD4 also has impact on glycosylase/lyase activity in a pathway of base excision repair. It has been reported th at mutation in MED1 activity may cause irregular DNA damage and tumor development.
ANTI-MBD4 Preparation Products And Raw materials
Raw materials
Preparation Products
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ANTI-MBD4 Suppliers
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