SPQ
- Product Name
- SPQ
- CAS No.
- 83907-40-8
- Chemical Name
- SPQ
- Synonyms
- SPQ;SPQ, INNER SALT;Inhibitor,inhibit,SPQ;3-(6-METHOXYQUINOLINE)PROPANESULFONATE;3-(6-METHOXYQUINOLINO)PROPANE SULFONATE;6-METHOXY-N-(3-SULFOPROPYL) QUINOLINIUM;6-Methoxy-1-(3-sulfopropyl)-quinolinium;1-(3-Sulfonatopropyl)-6-methoxyquinolinium;6-METHOXY-N-(3-SULFOPROPYL) QUINOLINIUM 98+%;3-(6-METHOXYQUINOLINIUM-1-YL)PROPANE-1-SULFONATE
- CBNumber
- CB7264588
- Molecular Formula
- C13H15NO4S
- Formula Weight
- 281.33
- MOL File
- 83907-40-8.mol
SPQ Property
- Melting point:
- 299°C dec.
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Soluble in water, dimethyl sulfoxide
- form
- powder
- color
- White
- λmax
- 344 nm
- Biological Applications
- Chloride indicator; nitrite indicator; diagnosis of diseases caused by elemental imbalances; detecting cancer cells,spores,stress biomarkers; identifying genes; studying chloride–bicarbonate exchange
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 27604
- Product name
- SPQ
- Packaging
- 100mg
- Price
- $85
- Updated
- 2024/03/01
- Product number
- 27604
- Product name
- SPQ
- Packaging
- 500mg
- Price
- $374
- Updated
- 2024/03/01
- Product number
- 27604
- Product name
- SPQ
- Packaging
- 250mg
- Price
- $198
- Updated
- 2024/03/01
- Product number
- M268500
- Product name
- 6-Methoxy-N-(3-sulfopropyl)quinolinium
- Packaging
- 100mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- CS-5923
- Product name
- SPQ
- Purity
- 99.97%
- Packaging
- 50mg
- Price
- $96
- Updated
- 2021/12/16
SPQ Chemical Properties,Usage,Production
Description
SPQ is a fluorescent chloride indicator. Its fluorescence is rapidly quenched by chloride in vitro. It has been used to assess voltage-sensitive chloride transport in placental microvillus vesicles. It has also been used to continuously quantify intracellular calcium efflux induced by parathyroid hormone, forskolin , and phorbol 12-myristate 13-acetate (PMA; ) in isolated human erythrocytes. In addition, SPQ has been used to determine the type of ion conductance induced by the cystic fibrosis transmembrane conductance regulator (CFTR) in HEK293 cells expressing pTrial10-CRTR2. SPQ displays excitation maxima of 320 and 350 nm and an emission maximum of 445 nm.
Chemical Properties
Off-White to Tan Cyrstalline Solid
Uses
SPQ is being used to examine and measure membrane chloride transport mechanisms.
References
[1] NICHOLAS P. ILLSLEY Alan S V. Membrane chloride transport measured using a chloride-sensitive fluorescent probe[J]. Biochemistry Biochemistry, 1987, 26 5: 1215-1219. DOI: 10.1021/bi00379a002
[2] LAURA SOLDATI . Chloride Fluxes Activated by Parathyroid Hormone in Human Erythrocytes[J]. Biochemical and biophysical research communications, 2000, 269 2: Pages 470-473. DOI: 10.1006/bbrc.2000.2320
[3] L J MACVINISH. Chloride secretion in the trachea of null cystic fibrosis mice: the effects of transfection with pTrial10-CFTR2.[J]. Journal of Physiology-London, 1997, 499 3: 677-687. DOI: 10.1113/jphysiol.1997.sp021960
SPQ Preparation Products And Raw materials
Raw materials
Preparation Products
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