ChemicalBook > CAS DataBase List > Dodecanoic acid ingenol ester
Dodecanoic acid ingenol ester
- Product Name
- Dodecanoic acid ingenol ester
- CAS No.
- 54706-70-6
- Chemical Name
- Dodecanoic acid ingenol ester
- Synonyms
- 13-Oxyingenoldodecagon;13-Oxyingenol dodecanoat;13-Oxyingenol Dodecanoate;Dodecanoic acid ingenol ester;Dodecanoic acid ingenol ester 54706-70-6;Dodecanoic acid, (1aR,2S,5R,5aR,6S,8aS,9R,10aS)-1,1a,2,5,5a,6,9,10-octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-10aH-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-10a-yl ester
- CBNumber
- CB72647453
- Molecular Formula
- C32H50O7
- Formula Weight
- 546.74
- MOL File
- 54706-70-6.mol
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Dodecanoic acid ingenol ester Property
- Melting point:
- >48°C (dec.)
- Boiling point:
- 655.2±55.0 °C(Predicted)
- Density
- 1.19±0.1 g/cm3 (20 ºC 760 Torr)
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 11.74±0.70(Predicted)
- color
- White to Off-White
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N-Bromosuccinimide Price
Usbiological
- Product number
- 411979
- Product name
- 13-Oxyingenol Dodecanoate
- Packaging
- 1mg
- Price
- $460
- Updated
- 2021/12/16
TRC
- Product number
- O870770
- Product name
- 13-OxyingenolDodecanoate
- Packaging
- 10mg
- Price
- $1190
- Updated
- 2021/12/16
Medical Isotopes, Inc.
- Product number
- 71877
- Product name
- 13-OxyingenolDodecanoate
- Packaging
- 1mg
- Price
- $650
- Updated
- 2021/12/16
Crysdot
- Product number
- CD31001537
- Product name
- Dodecanoicacidingenolester
- Purity
- 98+%
- Packaging
- 5mg
- Price
- $70
- Updated
- 2021/12/16
Crysdot
- Product number
- CD31001537
- Product name
- Dodecanoicacidingenolester
- Purity
- 98+%
- Packaging
- 10mg
- Price
- $126
- Updated
- 2021/12/16
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Dodecanoic acid ingenol ester Chemical Properties,Usage,Production
Chemical Properties
White powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Euphorbia lathyris L., a plant of the Euphorbiaceae family.
Uses
13-Oxyingenol Dodecanoate is a diterpene compound with antinematodal activity. Derivative of Ingenol (I655795), the analogue of Ingenol 3-Angelate (I655800), which has anti-tumor activity when used topically for the treatment of actinic keratosis.
in vivo
13-Oxyingenol-dodecanoate (2.5 mg/kg and 5 mg/kg; ip; every two days for two weeks) significantly inhibites the growth of transplanted tumors in a xenograft model by injecting H460 cells subcutaneously into nude mice[2].
| Animal Model: | xenograft model by injecting H460 cells into nude mice [2] |
| Dosage: | 2.5 mg/kg and 5 mg/kg; every two days for two weeks |
| Administration: | Intraperitoneal injection (i.p.) |
| Result: | nhibited the growth of transplanted tumors in nude mice and had no significant toxic effects on organ function. |
Dodecanoic acid ingenol ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Dodecanoic acid ingenol ester manufacturers
NanJing Spring & Autumn Biological Engineering CO., LTD.
- Product
- Dodecanoic acid ingenol ester 54706-70-6 54706-70-6
- Price
- US $1600.00/g
- Min. Order
- 10mg
- Purity
- 98.00%HPLC
- Supply Ability
- 1000.00 Kgs
- Release date
- 2019-06-27
Career Henan Chemical Co
- Product
- Dodecanoic acid ingenol ester 54706-70-6
- Price
- US $2.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2018-12-23
54706-70-6, Dodecanoic acid ingenol esterRelated Search:
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