tert-butyl (1S,3R)-3-aMinocyclohexylcarbaMate
- Product Name
- tert-butyl (1S,3R)-3-aMinocyclohexylcarbaMate
- CAS No.
- 1298101-47-9
- Chemical Name
- tert-butyl (1S,3R)-3-aMinocyclohexylcarbaMate
- Synonyms
- (1s,3r)-3-amino-1-(boc-amino)cyclohexane;tert-butyl (1S,3R)-3-aMinocyclohexylcarbaMate;tert-butyl N-[(1S,3R)-3-aminocyclohexyl]carbamate;Carbamic acid,N-[(1S,3R)-3-aminocyclohexyl]-, 1,1-dimethylethyl ester
- CBNumber
- CB72666982
- Molecular Formula
- C11H22N2O2
- Formula Weight
- 214.3
- MOL File
- 1298101-47-9.mol
tert-butyl (1S,3R)-3-aMinocyclohexylcarbaMate Property
- Boiling point:
- 322.1±31.0 °C(Predicted)
- Density
- 1.02±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 12.40±0.40(Predicted)
- Appearance
- White to off-white Solid
- optical activity
- -32.6°(C=0.01g/mL, MEOH, 20°C, 589nm)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 9131DT
- Product name
- Tert-Butyl((1S,3R)-3-aminocyclohexyl)carbamate
- Packaging
- 1g
- Price
- $532
- Updated
- 2021/12/16
- Product number
- A189556
- Product name
- tert-Butyl((1S,3R)-3-aminocyclohexyl)carbamate
- Purity
- 95%
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- A189556
- Product name
- tert-Butyl((1S,3R)-3-aminocyclohexyl)carbamate
- Purity
- 95%
- Packaging
- 250mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- L13449
- Product name
- (1S,3R)-3-Amino-1-(Boc-amino)cyclohexane
- Purity
- 97%
- Packaging
- 100MG
- Price
- $140
- Updated
- 2021/12/16
- Product number
- A189556
- Product name
- tert-Butyl((1S,3R)-3-aminocyclohexyl)carbamate
- Purity
- 95%
- Packaging
- 1g
- Price
- $233
- Updated
- 2021/12/16
tert-butyl (1S,3R)-3-aMinocyclohexylcarbaMate Chemical Properties,Usage,Production
Synthesis
1261225-48-2
1298101-47-9
The general procedure for the synthesis of tert-butyl ((1S,3R)-3-aminocyclohexyl)carbamate from benzyl ((1R,3S)-cyclohexane-1,3-diyl)dicarbamate (dextro) was as follows: to tert-butyl ((1S,3R)-3-(benzyloxycarbonylamino)cyclohexylcarbamate (10 g, 28.4 mmol) in EtOH (473 mL) A 10% w/w Pd/C (450 mg) was added to the degassed solution. The reaction mixture was stirred under H2 (1 atm) atmosphere for 5 hours. Upon completion of the reaction, the mixture was filtered through a Celite pad (and washed with EtOH) and the filtrate was concentrated under reduced pressure to afford tert-butyl ((1S,3R)-3-aminocyclohexyl)carbamate (6.08 g, 28.4 mmol, 100% yield) as a white solid.
References
[1] Patent: WO2015/58140, 2015, A1. Location in patent: Paragraph 00310
[2] Patent: WO2015/154039, 2015, A2. Location in patent: Paragraph 248; 249; 446; 447
[3] Patent: WO2016/58544, 2016, A1. Location in patent: Paragraph 165; 166; 375
tert-butyl (1S,3R)-3-aMinocyclohexylcarbaMate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from tert-butyl (1S,3R)-3-aMinocyclohexylcarbaMate manufacturers
- Product
- (1S,3R)-3-Amino-1-(Boc-amino)cyclohexane 1298101-47-9
- Price
- US $0.00/gm
- Min. Order
- 100gm
- Purity
- 99%min
- Supply Ability
- 100kgs
- Release date
- 2024-09-03
- Product
- tert-butyl (1S,3R)-3-aMinocyclohexylcarbaMate 1298101-47-9
- Price
- US $2.00/KG
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- ask
- Release date
- 2020-01-08