ChemicalBook > CAS DataBase List > S1RA (hydrochloride)
S1RA (hydrochloride)
- Product Name
- S1RA (hydrochloride)
- CAS No.
- 1265917-14-3
- Chemical Name
- S1RA (hydrochloride)
- Synonyms
- 177303;S1RA. HCL;S1RA HCl (E-52862);S1RA (E-52862) HCI;S1RA (hydrochloride);E52862 hydrochloride;E 52862 hydrochloride;E-52862 hydrochloride;E-52862 HYDROCHLORIDE;E52862 HYDROCHLORIDE;E 52862 HYDROCHLORIDE;4-(2-(5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy)ethyl)morpholine hydrochloride
- CBNumber
- CB72682021
- Molecular Formula
- C20H24ClN3O2
- Formula Weight
- 373.88
- MOL File
- 1265917-14-3.mol
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S1RA (hydrochloride) Property
- storage temp.
- -20°C (des.)
- solubility
- Soluble in DMSO (up to at least 25 mg/ml)
- form
- solid
- color
- Off-white
- Stability:
- Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-2188
- Product name
- S1RAhydrochloride
- Purity
- 99.24%
- Packaging
- 5mg
- Price
- $110
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-2188
- Product name
- S1RAhydrochloride
- Purity
- 99.24%
- Packaging
- 10mg
- Price
- $165
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- BS177543
- Product name
- S1RA hydrochloride
- Packaging
- 25mg
- Price
- $240
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- BS177543
- Product name
- S1RA hydrochloride
- Packaging
- 50mg
- Price
- $320
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-2188
- Product name
- S1RAhydrochloride
- Purity
- 99.24%
- Packaging
- 50mg
- Price
- $550
- Updated
- 2021/12/16
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S1RA (hydrochloride) Chemical Properties,Usage,Production
Description
S1RA (E-52862, 1265917-14-3) is a potent and selective σ1 antagonist with weak binding at σ2?(IC50?σ1 = 17nM, σ2 = 9300nM).1,2?S1RA abolished mechanical and thermal hyperalgesia in mice with carrageenan-induced acute inflammation by enhancing the action of endogenous opioid peptides of immune origin in a σ1 dependent manner.3?S1RA potentiated μ-opioid antinociception in mice in a σ-dependent manner.4?S1RA displayed neuroprotective effects in a mouse model of ischemic stroke.5
References
References/Citations
S1RA (hydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
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